serw-MX  [xml]  
 


    
 DeCS Categories

D08 Enzymes and Coenzymes .
D08.811 Enzymes .
D08.811.913 Transferases .
D08.811.913.696 Phosphotransferases .
D08.811.913.696.620 Phosphotransferases (Alcohol Group Acceptor) .
D08.811.913.696.620.682 Protein Kinases .
D08.811.913.696.620.682.725 Protein-Tyrosine Kinases .
D08.811.913.696.620.682.725.400 Receptor Protein-Tyrosine Kinases .
D08.811.913.696.620.682.725.400.009 ErbB Receptors .
D08.811.913.696.620.682.725.400.850 Receptors, Eph Family .
D12 Amino Acids, Peptides, and Proteins .
D12.776 Proteins .
D12.776.395 Glycoproteins .
D12.776.395.550 Membrane Glycoproteins .
D12.776.395.550.736 Signaling Lymphocytic Activation Molecule Family .
D12.776.543 Membrane Proteins .
D12.776.543.550 Membrane Glycoproteins .
D12.776.543.550.746 Signaling Lymphocytic Activation Molecule Family .
D12.776.543.750 Receptors, Cell Surface .
D12.776.543.750.630 Receptor Protein-Tyrosine Kinases .
D12.776.543.750.630.009 ErbB Receptors .
D12.776.543.750.630.500 Receptors, Eph Family .
D12.776.543.750.690 Receptors, Death Domain .
D12.776.543.750.705 Receptors, Immunologic .
D12.776.543.750.705.895 Receptors, Natural Killer Cell .
D12.776.543.750.705.895.500 Receptors, KIR .
D12.776.543.750.705.970 Signaling Lymphocytic Activation Molecule Family .
D12.776.543.750.750 Receptors, Peptide .
D12.776.543.750.750.400 Receptors, Growth Factor .
D12.776.543.750.750.400.074 ErbB Receptors .
 
 Terms
 Synonyms & Historicals
Documents
LILACS e MDL
 
Receptors, Death Domain .
Death Receptors .
Receptors, DR Family .
Receptors, Death Domain Family .
DR Family Receptors .
Death Domain Receptors .
A family of cell surface receptors that signal via a conserved domain that extends into the cell CYTOPLASM. The conserved domain is referred to as a DEATH DOMAIN due to the fact that many of these receptors are involved in APOPTOSIS signaling pathways. Several DEATH DOMAIN RECEPTOR SIGNALING ADAPTOR PROTEINS can bind to the death domains of the activated receptors and through a complex series of interactions activate apoptotic mediators such as CASPASES. .
1.00
3609
 
ErbB Receptors .
EGF Receptors .
Epidermal Growth Factor Receptor Family Proteins .
Erb-b2 Receptor Tyrosine Kinases .
HER Family Receptors .
Receptors, Epidermal Growth Factor .
Erb b2 Receptor Tyrosine Kinases .
Family Receptors, HER .
Receptors, EGF .
Receptors, Epidermal Growth Factor Urogastrone .
Receptors, ErbB .
Receptors, HER Family .
Receptors, Epidermal Growth Factor-Urogastrone .
Epidermal Growth Factor Receptors .
A family of structurally-related cell-surface receptors that signal through an intrinsic PROTEIN-TYROSINE KINASE. The receptors are activated upon binding of specific ligands which include EPIDERMAL GROWTH FACTORS, and NEUREGULINS. .
0.69
68127
 
Receptors, Eph Family .
Eph Receptors .
EphA Receptors .
EphB Receptor .
EphB Receptors .
Ephrin A Receptors .
Ephrin B Receptor .
Ephrin B Receptors .
Ephrin Receptors .
Receptor, Ephrin B .
Receptors, Eph .
Receptors, EphB .
Receptors, Ephrin .
Receptors, Ephrin A .
Eph Family Receptors .
Eph Receptor Tyrosine Kinase .
A large family of receptor protein-tyrosine kinases that are structurally-related. The name of this family of proteins derives from original protein Eph (now called the EPHA1 RECEPTOR), which was named after the cell line it was first discovered in: Erythropoietin-Producing human Hepatocellular carcinoma cell line. Members of this family have been implicated in regulation of cell-cell interactions involved in nervous system patterning and development. .
0.67
1649
 
Signaling Lymphocytic Activation Molecule Family .
SLAM Family Receptors .
SLAMF Receptors .
Signaling Lymphocytic Activation Molecule Family Receptors .
Signaling Lymphocytic Activation Molecule Receptors .
Signaling Lymphocytic Activation Molecules .
Type-I membrane glycoproteins that are expressed primarily on the surface of CD4 or CD8-positive T-CELLS; NATURAL KILLER CELLS; and some populations of B CELLS. They are characterized by an N-terminal, extracellular IMMUNOGLOBULIN-LIKE DOMAIN and a membrane-proximal IMMUNOGLOBULIN C2-SET DOMAIN. SLAMF receptors typically signal through homophilic interactions and are important for mediating the immune response and immune cell differentiation. .
0.64
1402
 
Receptors, KIR .
KIR Receptor .
Killer Cell Immunoglobulin-Like Receptor .
Killer Cell Immunoglobulin-Like Receptors .
Killer Immunoglobulin-Like Receptor .
Killer Immunoglobulin-Like Receptor (KIR) Family of Receptors .
Killer Inhibitory Receptor .
Receptor, Killer Inhibitory .
Receptor, p58 NK Cell .
p58 NK Cell Inhibitory Receptor .
p58 NK Cell Receptor .
p58 NK Cell Receptors .
p58 Natural Killer Cell Receptor .
Family Receptors, KIR .
Immunoglobulin-Like Receptor, Killer .
Inhibitory Receptor, Killer .
Inhibitory Receptors, Killer .
Killer Cell Immunoglobulin Like Receptor .
Killer Cell Immunoglobulin Like Receptors .
Killer Immunoglobulin Like Receptor .
Receptor, KIR .
Receptor, Killer Immunoglobulin-Like .
Receptors, KIR Family .
Receptors, Killer Inhibitory .
Killer Inhibitory Receptors .
KIR Family Receptors .
KIR Receptors .
A family of receptors found on NK CELLS that have specificity for a variety of HLA ANTIGENS. KIR receptors contain up to three different extracellular immunoglobulin-like domains referred to as D0, D1, and D2 and play an important role in blocking NK cell activation against cells expressing the appropriate HLA antigens thus preventing cell lysis. Although they are often referred to as being inhibitory receptors, a subset of KIR receptors may also play an activating role in NK cells. .
0.64
81770