serw-MX  [xml]  

 DeCS Categories

D23 Biological Factors .
D23.035 Alarmins .
D23.585 Pathogen-Associated Molecular Pattern Molecules .
 Synonyms & Historicals
Alarmins .
Alarmin .
Alarmin Proteins .
Damage-Associated Molecular Pattern Molecules .
Danger-Associated Molecular Pattern Molecules .
Damage Associated Molecular Pattern Molecules .
Danger Associated Molecular Pattern Molecules .
A structurally diverse group of endogenous molecules that are multifunctional, having physiological functions inside the cell, but when released from dying cells or from cells under stress or certain immune cells, they function to activate INNATE IMMUNITY. Uncontrolled and excessive release of alarmins may contribute to INFLAMMATION; CARCINOGENESIS, and NEOPLASM METASTASIS. Alarmins are also critical for heart and nerve tissue homeostasis. .
Pathogen-Associated Molecular Pattern Molecules .
Molecules, Pathogen-Associated Molecular Pattern .
Pathogen-Associated Molecular Patterns .
Molecular Patterns, Pathogen-Associated .
Molecules, Pathogen Associated Molecular Pattern .
Pathogen Associated Molecular Pattern Molecules .
Pathogen Associated Molecular Patterns .
Patterns, Pathogen-Associated Molecular .
Pathogens' molecules with specific sequence patterns that are recognized by PATTERN RECOGNITION RECEPTORS. They include microbial DNA, double-stranded RNA, surface glycoproteins, lipopolysaccharides, peptidoglycans, and lipoteichoic acid. .