serw-MX  [xml]  
 


    
 DeCS Categories

D08 Enzymes and Coenzymes .
D08.811 Enzymes .
D08.811.913 Transferases .
D08.811.913.696 Phosphotransferases .
D08.811.913.696.620 Phosphotransferases (Alcohol Group Acceptor) .
D08.811.913.696.620.682 Protein Kinases .
D08.811.913.696.620.682.725 Protein-Tyrosine Kinases .
D08.811.913.696.620.682.725.400 Receptor Protein-Tyrosine Kinases .
D08.811.913.696.620.682.725.400.005 Discoidin Domain Receptors .
D12 Amino Acids, Peptides, and Proteins .
D12.644 Peptides .
D12.644.360 Intracellular Signaling Peptides and Proteins .
D12.644.360.024 Adaptor Proteins, Signal Transducing .
D12.644.360.024.285 Death Domain Receptor Signaling Adaptor Proteins .
D12.644.360.075 Apoptosis Regulatory Proteins .
D12.644.360.075.421 Death Domain Receptor Signaling Adaptor Proteins .
D12.776 Proteins .
D12.776.157 Carrier Proteins .
D12.776.157.057 Adaptor Proteins, Signal Transducing .
D12.776.157.057.018 Death Domain Receptor Signaling Adaptor Proteins .
D12.776.476 Intracellular Signaling Peptides and Proteins .
D12.776.476.024 Adaptor Proteins, Signal Transducing .
D12.776.476.024.320 Death Domain Receptor Signaling Adaptor Proteins .
D12.776.476.075 Apoptosis Regulatory Proteins .
D12.776.476.075.421 Death Domain Receptor Signaling Adaptor Proteins .
D12.776.543 Membrane Proteins .
D12.776.543.750 Receptors, Cell Surface .
D12.776.543.750.630 Receptor Protein-Tyrosine Kinases .
D12.776.543.750.630.005 Discoidin Domain Receptors .
D12.776.543.750.685 Receptors, Collagen .
D12.776.543.750.685.050 Discoidin Domain Receptors .
D12.776.543.750.690 Receptors, Death Domain .
D12.776.543.750.690.725 Receptors, Tumor Necrosis Factor, Member 25 .
D12.776.543.750.705 Receptors, Immunologic .
D12.776.543.750.705.852 Receptors, Cytokine .
D12.776.543.750.705.852.760 Receptors, Tumor Necrosis Factor .
D12.776.543.750.705.852.760.505 Receptors, Tumor Necrosis Factor, Member 25 .
D12.776.543.750.705.880 Receptors, Mitogen .
D12.776.543.750.705.880.300 Discoidin Domain Receptors .
G02 Chemical Phenomena .
G02.111 Biochemical Phenomena .
G02.111.570 Molecular Structure .
G02.111.570.820 Molecular Conformation .
G02.111.570.820.709 Protein Conformation .
G02.111.570.820.709.275 Protein Structural Elements .
G02.111.570.820.709.275.750 Protein Domains .
G02.111.570.820.709.275.750.500 Protein Interaction Domains and Motifs .
G02.111.570.820.709.275.750.500.395 Death Domain Superfamily .
G02.111.570.820.709.275.750.500.395.500 Death Domain .
 
 Terms
 Synonyms & Historicals
Documents
LILACS e MDL
 
Receptors, Death Domain .
Death Receptors .
Receptors, DR Family .
Receptors, Death Domain Family .
DR Family Receptors .
Death Domain Receptors .
A family of cell surface receptors that signal via a conserved domain that extends into the cell CYTOPLASM. The conserved domain is referred to as a DEATH DOMAIN due to the fact that many of these receptors are involved in APOPTOSIS signaling pathways. Several DEATH DOMAIN RECEPTOR SIGNALING ADAPTOR PROTEINS can bind to the death domains of the activated receptors and through a complex series of interactions activate apoptotic mediators such as CASPASES. .
1.00
3609
 
Death Domain .
Death Domains .
A conserved protein interaction domain of the death domain superfamily that is structurally similar to the DEATH EFFECTOR DOMAIN and CASPASE RECRUITMENT DOMAIN. Death domains bind each other to form oligomers and occur on DEATH DOMAIN RECEPTORS, where they are required for APOPTOSIS signaling and non-apoptotic functions. .
0.80
10
 
Discoidin Domain Receptors .
DDR Proteins .
Discoidin Domain Receptor .
Proteins, DDR .
Receptor, Discoidin Domain .
Receptors, Discoidin Domain .
Receptor tyrosine kinases that bind COLLAGENS. They are characterized by the presence of extracellular DISCOIDIN DOMAINS that activate SIGNAL TRANSDUCTION PATHWAYS in response to collagen binding. They may also be cleaved by MATRIX METALLOPROTEINASES to mediate cell interactions with the EXTRACELLULAR MATRIX. .
0.70
0274
 
Death Domain Receptor Signaling Adaptor Proteins .
DED Signaling Adaptor Proteins .
DISC (Death Inducing Signaling Complex) .
Death Effector Domain Containing Proteins .
Death Effector Domain Signaling Adaptor Proteins .
Death Inducing Signaling Complex Proteins .
Fas-DISC Components .
fas Death-Inducing Signaling Complex Components .
Fas DISC Components .
fas Death Inducing Signaling Complex Components .
Intracellular signaling adaptor proteins that contain DEATH EFFECTOR DOMAINS and bind to the cytoplasmic DEATH DOMAIN region found on DEATH DOMAIN RECEPTORS. Many of the proteins in this class take part in intracellular signaling involving TUMOR NECROSIS FACTOR RECEPTORS. .
0.69
1431
 
Receptors, Tumor Necrosis Factor, Member 25 .
Apo-3 Receptor .
DR3 Receptor .
Death Receptor 3 .
Lymphocyte Associated Receptor of Death Protein .
TNFRSF25 Receptor .
TRAMP Receptor .
WSL-1 Protein .
Apo 3 Receptor .
Receptor, Apo-3 .
Receptor, DR3 .
Receptor, TNFRSF25 .
Receptor, TRAMP .
WSL 1 Protein .
Tumor Necrosis Factor Receptor Superfamily, Member 25 .
A tumor necrosis factor receptor subtype with specificity for TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 15. It is found in tissues containing LYMPHOCYTES and may play a role in regulating lymphocyte homeostasis and APOPTOSIS. The activated receptor signals via a conserved death domain that associates with specific TNF RECEPTOR-ASSOCIATED FACTORS in the CYTOPLASM. .
0.66
0222