serw-MX  [xml]  
 
    
 DeCS Categories

D02 Organic Chemicals .
D02.455 Hydrocarbons .
D02.455.426 Hydrocarbons, Cyclic .
D02.455.426.559 Hydrocarbons, Aromatic .
D02.455.426.559.847 Polycyclic Aromatic Hydrocarbons .
D02.455.426.559.847.562 Naphthacenes .
D02.455.426.559.847.562.050 Anthracyclines .
D02.455.426.559.847.562.050.200 Daunorubicin .
D02.455.426.559.847.562.050.200.150 Carubicin .
D03 Heterocyclic Compounds .
D03.633 Heterocyclic Compounds, Fused-Ring .
D03.633.100 Heterocyclic Compounds, 2-Ring .
D03.633.100.079 Benzazepines .
D03.633.100.079.080 Benzodiazepines .
D03.633.100.079.080.070 Benzodiazepinones .
D03.633.100.079.080.070.216 Diazepam .
D03.633.100.079.080.070.216.500 Nordazepam .
D04 Polycyclic Compounds .
D04.615 Polycyclic Aromatic Hydrocarbons .
D04.615.562 Naphthacenes .
D04.615.562.050 Anthracyclines .
D04.615.562.050.200 Daunorubicin .
D04.615.562.050.200.150 Carubicin .
D08 Enzymes and Coenzymes .
D08.244 Cytochromes .
D08.244.453 Cytochrome P-450 Enzyme System .
D08.244.453.860 Cytochrome P450 Family 3 .
D08.244.453.860.500 Cytochrome P-450 CYP3A .
D08.811 Enzymes .
D08.811.682 Oxidoreductases .
D08.811.682.662 Oxidoreductases Acting on CH-NH Group Donors .
D08.811.682.662.582 Oxidoreductases, N-Demethylating .
D08.811.682.662.582.353 Cytochrome P-450 CYP3A .
D08.811.682.690 Oxygenases .
D08.811.682.690.708 Mixed Function Oxygenases .
D08.811.682.690.708.170 Cytochrome P-450 Enzyme System .
D08.811.682.690.708.170.495 Cytochrome P450 Family 3 .
D08.811.682.690.708.170.495.500 Cytochrome P-450 CYP3A .
D09 Carbohydrates .
D09.408 Glycosides .
D09.408.051 Aminoglycosides .
D09.408.051.059 Anthracyclines .
D09.408.051.059.200 Daunorubicin .
D09.408.051.059.200.150 Carubicin .
D12 Amino Acids, Peptides, and Proteins .
D12.776 Proteins .
D12.776.422 Hemeproteins .
D12.776.422.220 Cytochromes .
D12.776.422.220.453 Cytochrome P-450 Enzyme System .
D12.776.422.220.453.860 Cytochrome P450 Family 3 .
D12.776.422.220.453.860.500 Cytochrome P-450 CYP3A .
G02 Chemical Phenomena .
G02.111 Biochemical Phenomena .
G02.111.188 Dealkylation .
G02.111.188.500 Demethylation .
G02.111.188.500.500 DNA Demethylation .
G02.607 Organic Chemistry Phenomena .
G02.607.141 Dealkylation .
G02.607.141.500 Demethylation .
G02.607.141.500.500 DNA Demethylation .
G03 Metabolism .
G03.219 Dealkylation .
G03.219.500 Demethylation .
G03.219.500.500 DNA Demethylation .
 
 Terms
 Synonyms & Historicals		Documents
LILACS e MDL		 
Carubicin .
Carminomicin .
Carminomycin I .
Carminomycin II .
Carminomycin III .
Carubicin Hydrochloride .
Demethyldaunomycin .
Demethyldaunorubicin .
Karminomicin .
NSC-180,024 .
NSC-180024 .
Rubeomycin A .
Rubeomycin A1 .
Hydrochloride, Carubicin .
NSC 180,024 .
NSC 180024 .
NSC180,024 .
NSC180024 .
Carminomycin .
Karminomycin .
A very toxic anthracycline-type antineoplastic related to DAUNORUBICIN, obtained from Actinomadura carminata. .
1.00
0340
 
Daunorubicin .
Cerubidine .
Dauno-Rubidomycine .
Daunoblastin .
Daunoblastine .
Daunorubicin Hydrochloride .
NSC-82151 .
Dauno Rubidomycine .
Hydrochloride, Daunorubicin .
NSC 82151 .
NSC82151 .
Daunomycin .
Rubidomycin .
Rubomycin .
A very toxic anthracycline aminoglycoside antineoplastic isolated from Streptomyces peucetius and others, used in treatment of LEUKEMIA and other NEOPLASMS. .
0.55
247542
 
Demethylation .
Oxidative Demethylation .
Demethylation, Oxidative .
Demethylations .
Demethylations, Oxidative .
Oxidative Demethylations .
Removal of one or more methyl groups from a chemical compound. .
0.55
04
 
Nordazepam .
Calmday .
N-Desalkylhalazepam .
N-Descyclopropylmethyl-Prazepam .
N-Descyclopropylmethylprazepam .
N-Destrifluoroethylhalazepam .
Nordaz .
Norprazepam .
Ro 5-2180 .
Tranxilium N .
Vegesan .
N Desalkylhalazepam .
N Descyclopropylmethyl Prazepam .
N Descyclopropylmethylprazepam .
N Destrifluoroethylhalazepam .
Ro 5 2180 .
Ro 52180 .
Dealkylprazepam .
Demethyldiazepam .
Deoxydemoxepam .
Desmethyldiazepam .
Nordiazepam .
An intermediate in the metabolism of DIAZEPAM to OXAZEPAM. It may have actions similar to those of diazepam. .
0.51
1469
 
Cytochrome P-450 CYP3A .
CYP3A4 .
CYP3A5 .
Cytochrome P-450 CYP3A4 .
Cytochrome P-450 CYP3A5 .
Cytochrome P-450IIIA .
Cytochrome P450 3A .
Cytochrome P450 3A4 .
Cytochrome P450 3A5 .
Erythromycin N-Demethylase .
Taurochenodeoxycholate 6-alpha-Monooxygenase .
3A5, Cytochrome P450 .
6-alpha-Monooxygenase, Taurochenodeoxycholate .
Cytochrome P 450 CYP3A .
Cytochrome P 450 CYP3A4 .
Cytochrome P 450 CYP3A5 .
Cytochrome P 450IIIA .
Erythromycin N Demethylase .
N-Demethylase, Erythromycin .
P-450 CYP3A, Cytochrome .
P-450 CYP3A4, Cytochrome .
P-450 CYP3A5, Cytochrome .
P-450IIIA, Cytochrome .
P450 3A, Cytochrome .
P450 3A5, Cytochrome .
Taurochenodeoxycholate 6 alpha Monooxygenase .
CYP3A .
A cytochrome P-450 suptype that has specificity for a broad variety of lipophilic compounds, including STEROIDS; FATTY ACIDS; and XENOBIOTICS. This enzyme has clinical significance due to its ability to metabolize a diverse array of clinically important drugs such as CYCLOSPORINE; VERAPAMIL; and MIDAZOLAM. This enzyme also catalyzes the N-demethylation of ERYTHROMYCIN. .
0.50
57569
 
DNA Demethylation .
DNA Demethylations .
Demethylation, DNA .
Demethylations, DNA .
Removal of methyl groups from DNA by enzymes (such as DIOXYGENASES and N-DEMETHYLASES) or by chemical reagents. .
0.47
11