serw-MX  [xml]  

 DeCS Categories

D08 Enzymes and Coenzymes .
D08.811 Enzymes .
D08.811.682 Oxidoreductases .
D08.811.682.690 Oxygenases .
D08.811.682.690.416 Dioxygenases .
D08.811.682.690.416.617 Prolyl Hydroxylases .
D08.811.682.690.416.617.750 Procollagen-Proline Dioxygenase .
D08.811.682.690.708 Mixed Function Oxygenases .
D08.811.682.690.708.694 Prolyl Hydroxylases .
D08.811.682.690.708.694.750 Procollagen-Proline Dioxygenase .
D27 Chemical Actions and Uses .
D27.505 Pharmacologic Actions .
D27.505.519 Molecular Mechanisms of Pharmacological Action .
D27.505.519.389 Enzyme Inhibitors .
D27.505.519.389.740 Prolyl-Hydroxylase Inhibitors .
D27.505.519.389.745 Protease Inhibitors .
 Synonyms & Historicals
Prolyl-Hydroxylase Inhibitors .
Proline Dioxygenase Inhibitors .
Proline Hydroxylase Inhibitors .
Dioxygenase Inhibitors, Proline .
Hydroxylase Inhibitors, Proline .
Inhibitors, Proline Dioxygenase .
Inhibitors, Proline Hydroxylase .
Inhibitors, Prolyl-Hydroxylase .
Prolyl Hydroxylase Inhibitors .
Compounds that inhibit the action of HYDROXYLASES that act on PROLINE to form HYDROXYPROLINE. .
Procollagen-Proline Dioxygenase .
Procollagen Prolyl 4-Hydroxylase .
4-Hydroxylase, Procollagen Prolyl .
Dioxygenase, Procollagen-Proline .
Hydroxylase, Protocollagen Prolyl .
Procollagen Proline Dioxygenase .
Procollagen Prolyl 4 Hydroxylase .
Prolyl 4-Hydroxylase, Procollagen .
Prolyl Hydroxylase, Protocollagen .
Protocollagen Prolyl Hydroxylase .
A mixed-function oxygenase that catalyzes the hydroxylation of a prolyl-glycyl containing peptide, usually in PROTOCOLLAGEN, to a hydroxyprolylglycyl-containing-peptide. The enzyme utilizes molecular OXYGEN with a concomitant oxidative decarboxylation of 2-oxoglutarate to SUCCINATE. The enzyme occurs as a tetramer of two alpha and two beta subunits. The beta subunit of procollagen-proline dioxygenase is identical to the enzyme PROTEIN DISULFIDE-ISOMERASES. .
Dioxygenases .
Non-heme iron-containing enzymes that incorporate two atoms of OXYGEN into the substrate. They are important in biosynthesis of FLAVONOIDS; GIBBERELLINS; and HYOSCYAMINE; and for degradation of AROMATIC HYDROCARBONS. .
Protease Inhibitors .
Antiproteases .
Protease Inhibitor .
Antagonists, Protease .
Hydrolase Inhibitors, Peptide .
Inhibitor, Protease .
Inhibitors, Endopeptidase .
Inhibitors, Peptidase .
Inhibitors, Peptide Hydrolase .
Inhibitors, Peptide Peptidohydrolase .
Inhibitors, Protease .
Peptidohydrolase Inhibitors, Peptide .
Endopeptidase Inhibitors .
Peptidase Inhibitors .
Peptide Hydrolase Inhibitors .
Peptide Peptidohydrolase Inhibitors .
Protease Antagonists .
Proteinase Inhibitors .
Compounds which inhibit or antagonize biosynthesis or actions of proteases (ENDOPEPTIDASES). .