serw-MX  [xml]  

 DeCS Categories

C04 Neoplasms .
C04.588 Neoplasms by Site .
C04.588.614 Nervous System Neoplasms .
C04.588.614.550 Paraneoplastic Syndromes, Nervous System .
C04.588.614.550.450 Limbic Encephalitis .
C04.730 Paraneoplastic Syndromes .
C04.730.856 Paraneoplastic Syndromes, Nervous System .
C04.730.856.437 Limbic Encephalitis .
C10 Nervous System Diseases .
C10.228 Central Nervous System Diseases .
C10.228.140 Brain Diseases .
C10.228.140.430 Encephalitis .
C10.228.140.430.525 Limbic Encephalitis .
C10.228.228 Central Nervous System Infections .
C10.228.228.245 Central Nervous System Viral Diseases .
C10. Limbic Encephalitis .
C10.228.228.291 Encephalomyelitis .
C10.228.440 Encephalomyelitis .
C10.574 Neurodegenerative Diseases .
C10.574.781 Paraneoplastic Syndromes, Nervous System .
C10.574.781.550 Limbic Encephalitis .
D12 Amino Acids, Peptides, and Proteins .
D12.776 Proteins .
D12.776.157 Carrier Proteins .
D12.776.157.725 RNA-Binding Proteins .
D12.776.157.725.813 RNA Recognition Motif Proteins .
D12.776.157.725.813.500 ELAV Proteins .
D12.776.157.725.813.500.250 ELAV-Like Protein 1 .
D12.776.157.725.813.500.500 ELAV-Like Protein 2 .
D12.776.157.725.813.500.750 ELAV-Like Protein 3 .
D12.776.157.725.813.500.875 ELAV-Like Protein 4 .
D12.776.631 Nerve Tissue Proteins .
D12.776.631.520 ELAV Proteins .
D12.776.631.520.500 ELAV-Like Protein 2 .
D12.776.631.520.750 ELAV-Like Protein 3 .
D12.776.631.520.875 ELAV-Like Protein 4 .
D12.776.664 Nucleoproteins .
D12.776.664.962 RNA-Binding Proteins .
D12.776.664.962.813 RNA Recognition Motif Proteins .
D12.776.664.962.813.500 ELAV Proteins .
D12.776.664.962.813.500.250 ELAV-Like Protein 1 .
D12.776.664.962.813.500.500 ELAV-Like Protein 2 .
D12.776.664.962.813.500.750 ELAV-Like Protein 3 .
D12.776.664.962.813.500.875 ELAV-Like Protein 4 .
 Synonyms & Historicals
Paraneoplastic Syndromes, Nervous System .
Autonomic Dysfunction, Paraneoplastic .
Nervous System Paraneoplastic Syndromes .
Paraneoplastic Neurologic Syndromes .
Autonomic Dysfunctions, Paraneoplastic .
Encephalomyelitis, Paraneoplastic .
Neurologic Syndrome, Paraneoplastic .
Neurologic Syndromes, Paraneoplastic .
Paraneoplastic Autonomic Dysfunctions .
Paraneoplastic Encephalomyelitides .
Paraneoplastic Neurologic Syndrome .
Syndrome, Paraneoplastic Neurologic .
Syndromes, Paraneoplastic Neurologic .
Paraneoplastic Autonomic Dysfunction .
Paraneoplastic Encephalomyelitis .
Degenerative or inflammatory conditions affecting the central or peripheral nervous system that develop in association with a systemic neoplasm without direct invasion by tumor. They may be associated with circulating antibodies that react with the affected neural tissue. (Intern Med 1996 Dec;35(12):925-9) .
ELAV-Like Protein 1 .
ELAVL1 protein .
HuR Antigen .
HuR Paraneoplastic Encephalomyelitis Antigen .
HuR Protein .
Antigen, HuR .
ELAV Like Protein 1 .
Protein, HuR .
protein, ELAVL1 .
An RRM protein that binds to the 3'-UTR region of mRNAs and increases their stability. In EMBRYONIC STEM CELLS, it binds to poly-U elements and AU-rich elements (AREs) in the 3'-UTR of target mRNAs and preferentially binds mRNAs that are not methylated by N6-methyladenosine (m6A), to stabilize them and promote differentiation. .
ELAV-Like Protein 3 .
ELAVL3 Protein .
HuC Antigen .
HuC Paraneoplastic Encephalomyelitis Antigen .
HuC Protein .
3, ELAV-Like Protein .
Antigen, HuC .
ELAV Like Protein 3 .
Protein 3, ELAV-Like .
Protein, ELAVL3 .
Protein, HuC .
A neural-specific RRM protein which contains three RNP-type RNA recognition motifs (RRMs). Human ELAVL3 is recognized by the anti-Hu serum antibody from patients with paraneoplastic encephalomyelitis and sensory neuronopathy (PEM/PSN). It also functions in neurogenesis. .
ELAV-Like Protein 2 .
ELAV (Embryonic Lethal, Abnormal Vision, Drosophila)-Like 2 (Hu Antigen B) .
ELAVL2 protein .
HuB Antigen .
HuB Paraneoplastic Encephalomyelitis Antigen .
HuB Protein .
2, ELAV-Like Protein .
Antigen, HuB .
ELAV Like Protein 2 .
Protein 2, ELAV-Like .
Protein, HuB .
protein, ELAVL2 .
A neural-specific RRM protein that binds to several 3'UTRs, including its own as well as that of PROTO-ONCOGENE PROTEINS C-FOS and ID DNA BINDING PROTEIN INHIBITOR. It binds through the recognition of a GAAA motif in the RNAs. .
ELAV Proteins .
ELAV Protein .
Embryonic Lethal, Abnormal Vision-Like Proteins .
Hu Antigens .
Antigens, Hu .
Embryonic Lethal, Abnormal Vision Like Proteins .
Protein, ELAV .
Proteins, ELAV .
Hu Paraneoplastic Encephalomyelitis Antigens .
A family of RRM PROTEINS that are homologues of ELAV protein, Drosophila. They were initially identified in humans as the targets of autoantibodies in patients with PARANEOPLASTIC ENCEPHALOMYELITIS. They regulate GENE EXPRESSION at the post-transcriptional level. .
ELAV-Like Protein 4 .
ELAVL4 Protein .
HuD Antigen .
HuD Paraneoplastic Encephalomyelitis Antigen .
HuD Protein .
Antigen, HuD .
ELAV Like Protein 4 .
Protein, ELAVL4 .
Protein, HuD .
An RRM protein which binds AU-rich sequences in the 3' UNTRANSLATED REGIONS of mRNAs for PROTO-ONCOGENE PROTEINS C-FOS; CYCLIN-DEPENDENT KINASE INHIBITOR P21; and GAP-43 PROTEIN. It functions in neuron-specific RNA processing. .
Encephalomyelitis .
Encephalomyelitis, Inflammatory .
Inflammatory Encephalomyelitis .
Myeloencephalitides .
Myeloencephalitis .
A general term indicating inflammation of the BRAIN and SPINAL CORD, often used to indicate an infectious process, but also applicable to a variety of autoimmune and toxic-metabolic conditions. There is significant overlap regarding the usage of this term and ENCEPHALITIS in the literature. .
Limbic Encephalitis .
Encephalitis, Limbic .
Encephalitides, Paraneoplastic Limbic .
Encephalitis, Paraneoplastic Limbic .
Limbic Encephalitis, Paraneoplastic .
Paraneoplastic Limbic Encephalitis .
A paraneoplastic syndrome marked by degeneration of neurons in the LIMBIC SYSTEM. Clinical features include HALLUCINATIONS, loss of EPISODIC MEMORY; ANOSMIA; AGEUSIA; TEMPORAL LOBE EPILEPSY; DEMENTIA; and affective disturbance (depression). Circulating anti-neuronal antibodies (e.g., anti-Hu; anti-Yo; anti-Ri; and anti-Ma2) and small cell lung carcinomas or testicular carcinoma are frequently associated with this syndrome. .