serw-MX  [xml]  
 


    
 DeCS Categories

B04 Viruses .
B04.123 Bacteriophages .
B04.123.205 Coliphages .
B04.123.205.320 Bacteriophage phi X 174 .
B04.123.470 Microviridae .
B04.123.470.500 Microvirus .
B04.123.470.500.320 Bacteriophage phi X 174 .
B04.280 DNA Viruses .
B04.280.470 Microviridae .
B04.280.470.500 Microvirus .
B04.280.470.500.320 Bacteriophage phi X 174 .
D08 Enzymes and Coenzymes .
D08.811 Enzymes .
D08.811.150 DNA Restriction-Modification Enzymes .
D08.811.150.240 DNA Modification Methylases .
D08.811.150.280 DNA Restriction Enzymes .
D08.811.277 Hydrolases .
D08.811.277.352 Esterases .
D08.811.277.352.335 Deoxyribonucleases .
D08.811.277.352.335.350 Endodeoxyribonucleases .
D08.811.277.352.335.350.300 DNA Restriction Enzymes .
D08.811.277.352.355 Endonucleases .
D08.811.277.352.355.325 Endodeoxyribonucleases .
D08.811.277.352.355.325.300 DNA Restriction Enzymes .
D08.811.913 Transferases .
D08.811.913.555 One-Carbon Group Transferases .
D08.811.913.555.500 Methyltransferases .
D08.811.913.555.500.350 DNA Modification Methylases .
D12 Amino Acids, Peptides, and Proteins .
D12.776 Proteins .
D12.776.097 Bacterial Proteins .
D12.776.097.890 Transcription Activator-Like Effectors .
D12.776.260 DNA-Binding Proteins .
D12.776.260.755 Trans-Activators .
D12.776.260.755.700 Transcription Activator-Like Effectors .
D12.776.826 Receptors, Cytoplasmic and Nuclear .
D12.776.826.750 Receptors, Steroid .
D12.776.826.750.150 Receptors, Androgen .
D12.776.930 Transcription Factors .
D12.776.930.900 Trans-Activators .
D12.776.930.900.550 Transcription Activator-Like Effectors .
D13 Nucleic Acids, Nucleotides, and Nucleosides .
D13.444 Nucleic Acids .
D13.444.308 DNA 12232 .
D13.444.308.283 DNA, Circular .
D23 Biological Factors .
D23.946 Toxins, Biological .
D23.946.896 Virulence Factors .
D23.946.896.490 Transcription Activator-Like Effectors .
E05 Investigative Techniques .
E05.393 Genetic Techniques .
E05.393.620 Nucleic Acid Amplification Techniques .
E05.393.620.500 Polymerase Chain Reaction .
F02 Psychological Phenomena .
F02.784 Psychology, Applied .
F02.784.412 Ergonomics .
F02.784.412.575 Man-Machine Systems .
G02 Chemical Phenomena .
G02.111 Biochemical Phenomena .
G02.111.570 Molecular Structure .
G02.111.570.820 Molecular Conformation .
G02.111.570.820.486 Nucleic Acid Conformation .
G02.111.570.820.486.212 DNA, Circular .
G04 Cell Physiological Phenomena .
G04.152 Cell Differentiation .
G05 Genetic Phenomena .
G05.360 Genetic Structures .
G05.360.580 Nucleic Acid Conformation .
G05.360.580.156 DNA, Circular .
H01 Natural Science Disciplines .
H01.158 Biological Science Disciplines .
H01.158.273 Biology .
H01.158.273.180 Computational Biology .
H01.158.273.180.350 Genomics .
H01.158.273.343 Genetics .
H01.158.273.343.350 Genomics .
J01 Technology, Industry, and Agriculture .
J01.293 Engineering .
J01.293.556 Ergonomics .
J01.293.556.441 Man-Machine Systems .
J01.897 Technology .
J01.897.441 Man-Machine Systems .
 
 Terms
 Synonyms & Historicals
Documents
LILACS e MDL
 
DNA Restriction Enzymes .
DNA Restriction Enzyme .
Restriction Endonuclease .
Endonuclease, Restriction .
Endonucleases, Restriction .
Enzymes, DNA Restriction .
Restriction Enzyme, DNA .
Restriction Enzymes, DNA .
Restriction Endonucleases .
Enzymes that are part of the restriction-modification systems. They catalyze the endonucleolytic cleavage of DNA sequences which lack the species-specific methylation pattern in the host cell's DNA. Cleavage yields random or specific double-stranded fragments with terminal 5'-phosphates. The function of restriction enzymes is to destroy any foreign DNA that invades the host cell. Most have been studied in bacterial systems, but a few have been found in eukaryotic organisms. They are also used as tools for the systematic dissection and mapping of chromosomes, in the determination of base sequences of DNAs, and have made it possible to splice and recombine genes from one organism into the genome of another. EC 3.21.1. .
1.00
6322541
 
DNA Modification Methylases .
Methylases, DNA Modification .
Methylases, Modification .
Methyltransferases, DNA Modification .
Modification Methylases, DNA .
Modification Methyltransferases, DNA .
DNA Modification Methyltransferases .
Modification Methylases .
Enzymes that are part of the restriction-modification systems. They are responsible for producing a species-characteristic methylation pattern, on either adenine or cytosine residues, in a specific short base sequence in the host cell's own DNA. This methylated sequence will occur many times in the host-cell DNA and remain intact for the lifetime of the cell. Any DNA from another species which gains entry into a living cell and lacks the characteristic methylation pattern will be recognized by the restriction endonucleases of similar specificity and destroyed by cleavage. Most have been studied in bacterial systems, but a few have been found in eukaryotic organisms. .
0.55
22690
 
Transcription Activator-Like Effectors .
TAL Effectors .
Effectors, TAL .
Effectors, Transcription Activator-Like .
Transcription Activator Like Effectors .
Virulence factors of pathogenic plant bacteria, such as XANTHOMONAS species, that bind to specific sequences in the PROMOTER REGIONS of host DNA to induce transcription of specific host genes. Variations in the DNA binding domain of TALE family members account for the variations in DNA specificity. The TALE DNA-binding domains are used in various GENETIC TECHNIQUES by fusing them with various DNA modifying enzymes to detect and manipulate sequence-specific targeted DNA sites. .
0.42
065
 
Polymerase Chain Reaction .
Anchored Polymerase Chain Reaction .
Inverse Polymerase Chain Reaction .
Nested Polymerase Chain Reaction .
PCR, Anchored .
PCR, Inverse .
PCR, Nested .
Polymerase Chain Reactions .
Reaction, Polymerase Chain .
Reactions, Polymerase Chain .
PCR 16999 .
Anchored PCR .
Inverse PCR .
Nested PCR .
In vitro method for producing large amounts of specific DNA or RNA fragments of defined length and sequence from small amounts of short oligonucleotide flanking sequences (primers). The essential steps include thermal denaturation of the double-stranded target molecules, annealing of the primers to their complementary sequences, and extension of the annealed primers by enzymatic synthesis with DNA polymerase. The reaction is efficient, specific, and extremely sensitive. Uses for the reaction include disease diagnosis, detection of difficult-to-isolate pathogens, mutation analysis, genetic testing, DNA sequencing, and analyzing evolutionary relationships. .
0.41
4447231618
 
Man-Machine Systems .
Man Machine Systems .
Man-Machine System .
System, Man-Machine .
Systems, Man-Machine .
A system in which the functions of the man and the machine are interrelated and necessary for the operation of the system. .
0.40
162548
 
Bacteriophage phi X 174 .
Phage phi X174 .
Coliphage phi X 174 .
Enterobacteria phage phi X 174 .
Phage phi X 174 .
phi X 174 Phage .
The type species of the genus MICROVIRUS. A prototype of the small virulent DNA coliphages, it is composed of a single strand of supercoiled circular DNA, which on infection, is converted to a double-stranded replicative form by a host enzyme. .
0.40
11112
 
DNA, Circular .
Circular DNA .
Circular DNAs .
DNAs, Circular .
Any of the covalently closed DNA molecules found in bacteria, many viruses, mitochondria, plastids, and plasmids. Small, polydisperse circular DNA's have also been observed in a number of eukaryotic organisms and are suggested to have homology with chromosomal DNA and the capacity to be inserted into, and excised from, chromosomal DNA. It is a fragment of DNA formed by a process of looping out and deletion, containing a constant region of the mu heavy chain and the 3'-part of the mu switch region. Circular DNA is a normal product of rearrangement among gene segments encoding the variable regions of immunoglobulin light and heavy chains, as well as the T-cell receptor. (Riger et al., Glossary of Genetics, 5th ed & Segen, Dictionary of Modern Medicine, 1992) .
0.39
45420
 
Genomics .
The systematic study of the complete DNA sequences (GENOME) of organisms. .
0.39
18134753
 
Cell Differentiation .
Differentiation, Cell .
Cell Differentiations .
Differentiations, Cell .
Progressive restriction of the developmental potential and increasing specialization of function that leads to the formation of specialized cells, tissues, and organs. .
0.39
394199848
 
Receptors, Androgen .
5 alpha-Dihydrotestosterone Receptor .
Androgen Receptor .
Dihydrotestosterone Receptors .
Receptor, Testosterone .
Receptors, Androgens .
Receptors, Dihydrotestosterone .
Receptors, Stanolone .
Stanolone Receptor .
Testosterone Receptor .
5 alpha Dihydrotestosterone Receptor .
Androgens Receptors .
Receptor, 5 alpha-Dihydrotestosterone .
Receptor, Androgen .
Receptor, Stanolone .
Stanolone Receptors .
alpha-Dihydrotestosterone Receptor, 5 .
Androgen Receptors .
Proteins, generally found in the CYTOPLASM, that specifically bind ANDROGENS and mediate their cellular actions. The complex of the androgen and receptor migrates to the CELL NUCLEUS where it induces transcription of specific segments of DNA. .
0.39
5913771