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 DeCS Categories

D08 Enzymes and Coenzymes .
D08.244 Cytochromes .
D08.244.453 Cytochrome P-450 Enzyme System .
D08.244.453.498 Cytochrome P450 Family 26 .
D08.244.453.498.500 Retinoic Acid 4-Hydroxylase .
D08.811 Enzymes .
D08.811.682 Oxidoreductases .
D08.811.682.690 Oxygenases .
D08.811.682.690.708 Mixed Function Oxygenases .
D08.811.682.690.708.170 Cytochrome P-450 Enzyme System .
D08.811.682.690.708.170.485 Cytochrome P450 Family 26 .
D08.811.682.690.708.170.485.500 Retinoic Acid 4-Hydroxylase .
D12 Amino Acids, Peptides, and Proteins .
D12.776 Proteins .
D12.776.422 Hemeproteins .
D12.776.422.220 Cytochromes .
D12.776.422.220.453 Cytochrome P-450 Enzyme System .
D12.776.422.220.453.498 Cytochrome P450 Family 26 .
D12.776.422.220.453.498.500 Retinoic Acid 4-Hydroxylase .
D27 Chemical Actions and Uses .
D27.505 Pharmacologic Actions .
D27.505.389 Metabolic Side Effects of Drugs and Substances .
D27.505.389.500 Cytochrome P-450 Enzyme Inhibitors .
D27.505.519 Molecular Mechanisms of Pharmacological Action .
D27.505.519.389 Enzyme Inhibitors .
D27.505.519.389.335 Cytochrome P-450 Enzyme Inhibitors .
 
 Terms
 Synonyms & Historicals
Documents
LILACS e MDL
 
Cytochrome P-450 Enzyme System .
CYP450 Family .
CYP450 Superfamily .
Cytochrome P-450 Enzymes .
Cytochrome P-450 Families .
Cytochrome P-450 Monooxygenase .
Cytochrome P-450 Oxygenase .
Cytochrome P-450 Superfamily .
Cytochrome P450 .
Cytochrome P450 Superfamily .
Cytochrome p450 Families .
P-450 Enzymes .
P450 Enzymes .
Cytochrome P 450 .
Cytochrome P 450 Dependent Monooxygenase .
Cytochrome P 450 Enzyme System .
Cytochrome P 450 Enzymes .
Cytochrome P 450 Families .
Cytochrome P 450 Monooxygenase .
Cytochrome P 450 Oxygenase .
Cytochrome P 450 Superfamily .
Enzymes, Cytochrome P-450 .
Enzymes, P-450 .
Enzymes, P450 .
Monooxygenase, Cytochrome P-450 .
Monooxygenase, Cytochrome P-450-Dependent .
P 450 Enzymes .
P-450 Enzymes, Cytochrome .
Superfamily, CYP450 .
Superfamily, Cytochrome P-450 .
Superfamily, Cytochrome P450 .
Cytochrome P-450 .
Cytochrome P-450-Dependent Monooxygenase .
A superfamily of hundreds of closely related HEMEPROTEINS found throughout the phylogenetic spectrum, from animals, plants, fungi, to bacteria. They include numerous complex monooxygenases (MIXED FUNCTION OXYGENASES). In animals, these P-450 enzymes serve two major functions: (1) biosynthesis of steroids, fatty acids, and bile acids; (2) metabolism of endogenous and a wide variety of exogenous substrates, such as toxins and drugs (BIOTRANSFORMATION). They are classified, according to their sequence similarities rather than functions, into CYP gene families (>40% homology) and subfamilies (>59% homology). For example, enzymes from the CYP1, CYP2, and CYP3 gene families are responsible for most drug metabolism. .
1.00
4439776
 
/enzymology .
/enzyme activity .
/enzymes .
Used with organisms, except vertebrates, and with organs and tissues. It is also used with diseases for enzymes during the course of the disease, but excludes diagnostic enzyme tests, for which "diagnosis" is used. .
0.71
 
Enzymes .
Biocatalysts .
Biological molecules that possess catalytic activity. They may occur naturally or be synthetically created. Enzymes are usually proteins, however CATALYTIC RNA and CATALYTIC DNA molecules have also been identified. .
0.71
48425937
 
Cytochrome P-450 Enzyme Inhibitors .
Cytochrome P-450 Inhibitors .
Cytochrome P-450 Monooxygenase Inhibitors .
Cytochrome P-450 Oxygenase Inhibitors .
Cytochrome P-450-Dependent Monooxygenase Inhibitors .
P-450 Enzyme Inhibitors .
P450 Enzyme Inhibitors .
Cytochrome P 450 Dependent Monooxygenase Inhibitors .
Cytochrome P 450 Enzyme Inhibitors .
Cytochrome P 450 Inhibitors .
Cytochrome P 450 Monooxygenase Inhibitors .
Cytochrome P 450 Oxygenase Inhibitors .
Enzyme Inhibitors, P-450 .
Enzyme Inhibitors, P450 .
Inhibitors, Cytochrome P-450 .
Inhibitors, P-450 Enzyme .
Inhibitors, P450 Enzyme .
P 450 Enzyme Inhibitors .
P-450 Inhibitors, Cytochrome .
Drugs and compounds which inhibit or antagonize the biosynthesis or actions of CYTOCHROME P-450 ENZYMES. .
0.69
05278
 
Retinoic Acid 4-Hydroxylase .
CYP26A1 .
CYP26A1 Enzyme .
CYP26B1 .
CYP450 4-Hydroxylase .
Cytochrome P-450 26B1 .
Cytochrome P-450 CYP26B1 .
Cytochrome P450 26A1 Enzyme .
Cytochrome P450 4-Hydroxylase .
P450RAI .
RA-4-Hydroxylase .
Retinoic Acid-Metabolizing Enzyme, CYP26B1 .
CYP26B1, Cytochrome P-450 .
Cytochrome P 450 CYP26B1 .
Cytochrome P450 4 Hydroxylase .
Enzyme, CYP26A1 .
RA 4 Hydroxylase .
Retinoic Acid 4 Hydroxylase .
Retinoic Acid Metabolizing Enzyme, CYP26B1 .
A cytochrome P450 enzyme that resides in the ENDOPLASMIC RETICULUM. It catalyzes the conversion of trans-RETINOIC ACID to 4-hydroxyretinoic acid. .
0.56
0417
 
Enzymes and Coenzymes .
Coenzymes and Enzymes .
Enzymes, Coenzymes, and Enzyme Inhibitors .
Biological catalysts and their cofactors. .
0.54
96