serw-MX  [xml]  

 DeCS Categories

D02 Organic Chemicals .
D02.886 Sulfur Compounds .
D02.886.590 Sulfones .
D02.886.590.700 Sulfonamides .
D02.886.590.700.135 Benzothiadiazines .
D02.886.590.700.135.261 Chlorothiazide .
D02.886.590.700.135.261.476 Hydrochlorothiazide .
D02.886.655 Thiazides .
D02.886.655.500 Benzothiadiazines .
D02.886.655.500.261 Chlorothiazide .
D02.886.655.500.261.476 Hydrochlorothiazide .
D03 Heterocyclic Compounds .
D03.633 Heterocyclic Compounds, Fused-Ring .
D03.633.100 Heterocyclic Compounds, 2-Ring .
D03.633.100.174 Benzothiadiazines .
D03.633.100.174.261 Chlorothiazide .
D03.633. Hydrochlorothiazide .
E05 Investigative Techniques .
E05.196 Chemistry Techniques, Analytical .
E05.196.566 Mass Spectrometry .
E05.196.566.600 Spectrometry, Mass, Electrospray Ionization .
 Synonyms & Historicals
Hydrochlorothiazide .
Dichlothiazide .
Dihydrochlorothiazide .
Esidrex .
Esidrix .
HCTZ 5279 .
Hypothiazide .
Oretic .
Sectrazide .
A thiazide diuretic often considered the prototypical member of this class. It reduces the reabsorption of electrolytes from the renal tubules. This results in increased excretion of water and electrolytes, including sodium, potassium, chloride, and magnesium. It is used in the treatment of several disorders including edema, hypertension, diabetes insipidus, and hypoparathyroidism. .
Spectrometry, Mass, Electrospray Ionization .
Mass Spectrometry, ESI .
Spectrometry, ESI Mass .
ESI Mass Spectrometry .
Electrospray Ionization Mass Spectrometry .
A mass spectrometry technique used for analysis of nonvolatile compounds such as proteins and macromolecules. The technique involves preparing electrically charged droplets from analyte molecules dissolved in solvent. The electrically charged droplets enter a vacuum chamber where the solvent is evaporated. Evaporation of solvent reduces the droplet size, thereby increasing the coulombic repulsion within the droplet. As the charged droplets get smaller, the excess charge within them causes them to disintegrate and release analyte molecules. The volatilized analyte molecules are then analyzed by mass spectrometry. .