ATP Binding Cassette Transporter, Sub-Family B. ATP-Binding Cassette, Sub-Family B Proteins . ATP Binding Cassette Transporter, Sub Family B . ATP Binding Cassette, Sub Family B Proteins . P Glycoproteins . P-Glycoproteins . Multidrug Resistance Proteins . A subfamily of transmembrane proteins from the superfamily of ATP-BINDING CASSETTE TRANSPORTERS that are closely related in sequence to ATP-BINDING CASSETTE, SUB-FAMILY B, MEMBER 1. When overexpressed, they function as ATP-dependent efflux pumps able to extrude lipophilic drugs, especially ANTINEOPLASTIC AGENTS, from cells causing multidrug resistance (DRUG RESISTANCE, MULTIPLE). Although ATP BINDING CASSETTE TRANSPORTER, SUB-FAMILY B share functional similarities to MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS they are two distinct subclasses of ATP-BINDING CASSETTE TRANSPORTERS, and have little sequence homology. . 0.82
Gene Products, env. env Antigens . env Glycoproteins . env Polyprotein . Antigens, env . Polyprotein, env . Polyproteins, env . env Gene Products . env Polyproteins . env Protein . Retroviral proteins, often glycosylated, coded by the envelope (env) gene. They are usually synthesized as protein precursors (POLYPROTEINS) and later cleaved into the final viral envelope glycoproteins by a viral protease. . 0.81
ATP-Binding Cassette, Sub-Family B, Member 1. ABCB1 Protein . CD243 Antigen . PGY-1 Protein . Antigen, CD243 . P Glycoprotein . PGY 1 Protein . MDR1 Protein . Multidrug Resistance Protein 1 . P-Glycoprotein . MULTIDRUG TRANSPORTER . A 170-kDa transmembrane glycoprotein from the superfamily of ATP-BINDING CASSETTE TRANSPORTERS. It serves as an ATP-dependent efflux pump for a variety of chemicals, including many ANTINEOPLASTIC AGENTS. Overexpression of this glycoprotein is associated with multidrug resistance (see DRUG RESISTANCE, MULTIPLE). . 0.79
Platelet Membrane Glycoproteins. PM-GPs . Platelet Glycoproteins . Glycoproteins, Platelet . Glycoproteins, Platelet Membrane . Membrane Glycoproteins, Platelet . Surface glycoproteins on platelets which have a key role in hemostasis and thrombosis such as platelet adhesion and aggregation. Many of these are receptors. . 0.77
