serw-MX  [xml]  
 


    
 DeCS Categories

D02 Organic Chemicals .
D02.065 Amides .
D02.065.884 Sulfonamides .
D02.065.884.575 Mefruside .
D02.241 Carboxylic Acids .
D02.241.081 Acids, Acyclic .
D02.241.081.018 Acetates .
D02.241.081.018.386 Glycolates .
D02.241.081.018.386.682 Phenoxyacetates .
D02.241.081.018.386.682.300 Ethacrynic Acid .
D02.241.511 Hydroxy Acids .
D02.241.511.316 Glycolates .
D02.241.511.316.682 Phenoxyacetates .
D02.241.511.316.682.200 Ethacrynic Acid .
D02.886 Sulfur Compounds .
D02.886.590 Sulfones .
D02.886.590.700 Sulfonamides .
D02.886.590.700.135 Benzothiadiazines .
D02.886.590.700.575 Mefruside .
D02.886.655 Thiazides .
D02.886.655.500 Benzothiadiazines .
D03 Heterocyclic Compounds .
D03.633 Heterocyclic Compounds, Fused-Ring .
D03.633.100 Heterocyclic Compounds, 2-Ring .
D03.633.100.174 Benzothiadiazines .
D12 Amino Acids, Peptides, and Proteins .
D12.776 Proteins .
D12.776.157 Carrier Proteins .
D12.776.157.530 Membrane Transport Proteins .
D12.776.157.530.450 Ion Pumps .
D12.776.157.530.450.625 Symporters .
D12.776.157.530.450.625.374 Sodium Chloride Symporters .
D27 Chemical Actions and Uses .
D27.505 Pharmacologic Actions .
D27.505.519 Molecular Mechanisms of Pharmacological Action .
D27.505.519.562 Membrane Transport Modulators .
D27.505.519.562.812 Sodium Chloride Symporter Inhibitors .
D27.505.519.562.906 Sodium Potassium Chloride Symporter Inhibitors .
D27.505.696 Physiological Effects of Drugs .
D27.505.696.560 Natriuretic Agents .
D27.505.696.560.500 Diuretics .
D27.505.696.560.500.863 Sodium Chloride Symporter Inhibitors .
D27.505.696.560.500.931 Sodium Potassium Chloride Symporter Inhibitors .
 
 Terms
 Synonyms & Historicals
Documents
LILACS e MDL
 
Thiazides .
Heterocyclic compounds with SULFUR and NITROGEN in the ring. This term commonly refers to the BENZOTHIADIAZINES that inhibit SODIUM-POTASSIUM-CHLORIDE SYMPORTERS and are used as DIURETICS. .
1.00
3185
 
Benzothiadiazines .
Heterocyclic compounds of a ring with SULFUR and two NITROGEN atoms fused to a BENZENE ring. Members inhibit SODIUM-POTASSIUM-CHLORIDE SYMPORTERS and are used as DIURETICS. .
0.66
02627
 
Sodium Potassium Chloride Symporter Inhibitors .
Bumetanide Sensitive Na-K-Cl-Transporter Inhibitors .
High Ceiling Diuretics .
Loop Diuretics .
Na-K-CL Symporter Inhibitors .
Sodium Potassium Chloride Cotransporter Inhibitors .
Bumetanide Sensitive Na K Cl Transporter Inhibitors .
Ceiling Diuretics, High .
Diuretics, High Ceiling .
Diuretics, Loop .
Inhibitors, Na-K-CL Symporter .
Na K CL Symporter Inhibitors .
Symporter Inhibitors, Na-K-CL .
Agents that inhibit SODIUM-POTASSIUM-CHLORIDE SYMPORTERS which are concentrated in the thick ascending limb at the junction of the LOOP OF HENLE and KIDNEY TUBULES, DISTAL. They act as DIURETICS. Excess use is associated with HYPOKALEMIA and HYPERGLYCEMIA. .
0.41
2805
 
Sodium Chloride Symporter Inhibitors .
Benzothiadiazine Diuretics .
Diuretics, Thiazide .
Potassium Depleting Diuretics .
Sodium Chloride Cotransporter Inhibitors .
Thiazide Diuretics .
Thiazide Sensitive NaCl Cotransporter Inhibitors .
Diuretics, Benzothiadiazine .
Diuretics, Potassium Depleting .
Diuretics, Thiazide .
Benzothiadiazine Diuretics .
Thiazide Diuretics .
Agents that inhibit SODIUM CHLORIDE SYMPORTERS. They act as DIURETICS. Excess use is associated with HYPOKALEMIA. .
0.35
362838
 
Ethacrynic Acid .
Edecrin .
Etacrynic Acid .
Ethacrinic Acid .
Ethacrynate Sodium .
Ethacrynic Acid, Sodium Salt .
Hydromedin .
Acid, Etacrynic .
Acid, Ethacrinic .
Acid, Ethacrynic .
Sodium, Ethacrynate .
A compound that inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of Henle, but also in the proximal and distal tubules. This pharmacological action results in excretion of these ions, increased urinary output, and reduction in extracellular fluid. This compound has been classified as a loop or high ceiling diuretic. .
0.35
 
Sodium Chloride Symporters .
Na-Cl-Symporters .
Sodium Chloride Cotransporters .
Sodium-Chloride Cotransporter .
Sodium-Chloride Transporter .
Chloride Cotransporters, Sodium .
Chloride Symporters, Sodium .
Cotransporter, Sodium-Chloride .
Cotransporters, Sodium Chloride .
Na Cl Symporters .
Sodium Chloride Cotransporter .
Sodium Chloride Transporter .
Symporters, Sodium Chloride .
Transporter, Sodium-Chloride .
A subclass of symporters found in KIDNEY TUBULES, DISTAL that are the major pathway for salt resorption. Inhibition of these symporters by BENZOTHIADIAZINES is the basis of action of some DIURETICS. .
0.33
2476
 
Mefruside .
A benzene-sulfonamide-furan. It is used as a diuretic that affects the concentrating ability of the KIDNEY, increases SODIUM CHLORIDE excretion, but may not spare POTASSIUM. It inhibits CARBONIC ANHYDRASES and may increase the blood URIC ACID level. .
0.33