serw-MX  [xml]  
 


    
 DeCS Categories

D02 Organic Chemicals .
D02.092 Amines .
D02.092.782 Polyamines .
D02.092.782.258 Diamines .
D02.092.782.258.368 Ethylenediamines .
D02.092.782.258.368.500 Methapyrilene .
D03 Heterocyclic Compounds .
D03.383 Heterocyclic Compounds, 1-Ring .
D03.383.725 Pyridines .
D03.383.725.050 Aminopyridines .
D03.383.725.050.440 Methapyrilene .
D03.383.725.259 Doxylamine .
D03.383.725.620 Pheniramine .
D03.383.725.620.129 Brompheniramine .
D27 Chemical Actions and Uses .
D27.505 Pharmacologic Actions .
D27.505.519 Molecular Mechanisms of Pharmacological Action .
D27.505.519.625 Neurotransmitter Agents .
D27.505.519.625.375 Histamine Agents .
D27.505.519.625.375.400 Histamine Agonists .
D27.505.519.625.375.425 Histamine Antagonists .
D27.505.519.625.375.425.400 Histamine H1 Antagonists .
D27.505.519.625.375.425.400.500 Histamine H1 Antagonists, Non-Sedating .
D27.505.696 Physiological Effects of Drugs .
D27.505.696.577 Neurotransmitter Agents .
D27.505.696.577.375 Histamine Agents .
D27.505.696.577.375.400 Histamine Agonists .
D27.505.696.577.375.425 Histamine Antagonists .
D27.505.696.577.375.425.400 Histamine H1 Antagonists .
D27.505.696.577.375.425.400.500 Histamine H1 Antagonists, Non-Sedating .
 
 Terms
 Synonyms & Historicals
Documents
LILACS e MDL
 
Methapyrilene .
Lullamin .
N,N-Dimethyl-N'-2-pyridinyl-N'-(2-thienylmethyl)-1,2-ethanediamine .
Restryl .
Tenalin .
Thionylan .
Thenylpyramine .
Histamine H1 antagonist with sedative action used as a hypnotic and in allergies. .
1.00
0145
 
Histamine H1 Antagonists, Non-Sedating .
H1 Antihistamines, Non-Sedating .
Second Generation Antihistamines .
Second Generation H1 Antagonists .
Third Generation H1 Antagonists .
Antihistamines, Second Generation .
H1 Antihistamines, Non Sedating .
Histamine H1 Antagonists, Non Sedating .
Non-Sedating H1 Antihistamines .
A class of non-sedating drugs that bind to but do not activate histamine receptors (DRUG INVERSE AGONISM), thereby blocking the actions of histamine or histamine agonists. These antihistamines represent a heterogenous group of compounds with differing chemical structures, adverse effects, distribution, and metabolism. Compared to the early (first generation) antihistamines, these non-sedating antihistamines have greater receptor specificity, lower penetration of BLOOD-BRAIN BARRIER, and are less likely to cause drowsiness or psychomotor impairment. .
0.58
5939
 
Brompheniramine .
Brompheniramine Maleate .
Brompheniramine Maleate (1:1) .
Chlorphed .
Dimetane .
Dimetane-Ten .
Dimetapp Allergy .
Oraminic-2 .
Dimetane Ten .
Maleate, Brompheniramine .
Oraminic 2 .
p Bromdylamine .
para Bromdylamine .
p-Bromdylamine .
para-Bromdylamine .
Histamine H1 antagonist used in treatment of allergies, rhinitis, and urticaria. .
0.55
3297
 
Histamine H1 Antagonists .
Antagonists, Histamine H1 .
Antagonists, Histamine H1 Receptor .
Antihistamines, Sedating .
Blockaders, Histamine H1 Receptor .
First Generation H1 Antagonists .
H1 Receptor Blockaders .
Histamine H1 Blockers .
Receptor Blockaders, H1 .
Classical Antihistamines .
Classical Antihistaminics .
H1 Antagonists, Histamine .
H1 Antihistaminics .
Sedating Antihistamines .
Antihistaminics, Classical .
Antihistaminics, H1 .
Histamine H1 Receptor Antagonists .
Histamine H1 Receptor Blockaders .
Antihistamines, Classical .
Drugs that selectively bind to but do not activate histamine H1 receptors, thereby blocking the actions of endogenous histamine. Included here are the classical antihistaminics that antagonize or prevent the action of histamine mainly in immediate hypersensitivity. They act in the bronchi, capillaries, and some other smooth muscles, and are used to prevent or allay motion sickness, seasonal rhinitis, and allergic dermatitis and to induce somnolence. The effects of blocking central nervous system H1 receptors are not as well understood. .
0.55
24311639
 
Doxylamine .
Histamine H1 antagonist with pronounced sedative properties. It is used in allergies and as an antitussive, antiemetic, and hypnotic. Doxylamine has also been administered in veterinary applications and was formerly used in PARKINSONISM. .
0.53
3345
 
Histamine Agonists .
H1 Agonist .
H1 Agonists .
H2 Agonist .
H2 Agonists .
H3 Agonist .
H3 Agonists .
Histamine Agonist .
Histamine H1 Agonist .
Histamine H1 Receptor Agonist .
Histamine H1 Receptor Agonists .
Histamine H2 Agonist .
Histamine H2 Receptor Agonist .
Histamine H2 Receptor Agonists .
Histamine H3 Agonist .
Histamine H3 Receptor Agonists .
Histaminergic Agonist .
Histaminergic Agonists .
Agonist, H1 .
Agonist, H2 .
Agonist, H3 .
Agonist, Histamine .
Agonist, Histamine H1 .
Agonist, Histamine H2 .
Agonist, Histamine H3 .
Agonist, Histaminergic .
Agonists, H1 .
Agonists, H2 .
Agonists, H3 .
Agonists, Histamine .
Agonists, Histamine H1 .
Agonists, Histamine H2 .
Agonists, Histamine H3 .
Agonists, Histaminergic .
H1 Agonist, Histamine .
H1 Agonists, Histamine .
H2 Agonist, Histamine .
H2 Agonists, Histamine .
H3 Agonist, Histamine .
H3 Agonists, Histamine .
Histamine H1 Agonists .
Histamine H2 Agonists .
Histamine H3 Agonists .
Drugs that bind to and activate histamine receptors. Although they have been suggested for a variety of clinical applications histamine agonists have so far been more widely used in research than therapeutically. .
0.50
111225