serw-MX  [xml]  

 DeCS Categories

D12 Amino Acids, Peptides, and Proteins .
D12.776 Proteins .
D12.776.395 Glycoproteins .
D12.776.395.550 Membrane Glycoproteins .
D12.776.395.550.489 Histocompatibility Antigens Class I .
D12.776.395.550.509 Histocompatibility Antigens Class II .
D12.776.543 Membrane Proteins .
D12.776.543.550 Membrane Glycoproteins .
D12.776.543.550.439 Histocompatibility Antigens Class I .
D12.776.543.550.440 Histocompatibility Antigens Class II .
D23 Biological Factors .
D23.050 Antigens .
D23.050.301 Antigens, Surface .
D23.050.301.500 Histocompatibility Antigens .
D23.050.301.500.100 Histocompatibility Antigens Class I .
D23.050.301.500.400 Histocompatibility Antigens Class II .
D23.050.705 Isoantigens .
D23.050.705.552 Histocompatibility Antigens .
D23.050.705.552.100 Histocompatibility Antigens Class I .
D23.050.705.552.410 Histocompatibility Antigens Class II .
 Synonyms & Historicals
Histocompatibility Antigens Class I .
Class I Histocompatibility Antigens .
Class I Human Antigens .
Class I Major Histocompatibility Antigens .
Human Class I Antigens .
Antigens, Class I .
I Antigens, Class .
Class I Antigens .
Membrane glycoproteins consisting of an alpha subunit and a BETA 2-MICROGLOBULIN beta subunit. In humans, highly polymorphic genes on CHROMOSOME 6 encode the alpha subunits of class I antigens and play an important role in determining the serological specificity of the surface antigen. Class I antigens are found on most nucleated cells and are generally detected by their reactivity with alloantisera. These antigens are recognized during GRAFT REJECTION and restrict cell-mediated lysis of virus-infected cells. .
Histocompatibility Antigens Class II .
Class II Antigen .
Class II Histocompatibility Antigens .
Class II Major Histocompatibility Antigens .
I-A Antigen .
I-A-Antigen .
IA Antigen .
Antigen, Class II .
Antigen, I-A .
Antigen, IA .
Antigens, Class II .
Antigens, Ia .
Antigens, Ia-Like .
Antigens, Immune-Associated .
Antigens, Immune-Response-Associated .
I A Antigen .
Ia Like Antigens .
Immune Associated Antigens .
Immune Response Associated Antigens .
Antigens, Immune Response .
Class II Antigens .
Ia Antigens .
Ia-Like Antigens .
Immune-Associated Antigens .
Immune Response Antigens .
Immune-Response-Associated Antigens .
Large, transmembrane, non-covalently linked glycoproteins (alpha and beta). Both chains can be polymorphic although there is more structural variation in the beta chains. The class II antigens in humans are called HLA-D ANTIGENS and are coded by a gene on chromosome 6. In mice, two genes named IA and IE on chromosome 17 code for the H-2 antigens. The antigens are found on B-lymphocytes, macrophages, epidermal cells, and sperm and are thought to mediate the competence of and cellular cooperation in the immune response. The term IA antigens used to refer only to the proteins encoded by the IA genes in the mouse, but is now used as a generic term for any class II histocompatibility antigen. .
Histocompatibility Antigens .
Antigens, Transplantation .
Histocompatibility Antigen .
LD Antigens .
SD Antigens .
Antigen, Histocompatibility .
Antigens, Histocompatibility .
Antigens, LD .
Antigens, SD .
Transplantation Antigens .
A group of antigens that includes both the major and minor histocompatibility antigens. The former are genetically determined by the major histocompatibility complex. They determine tissue type for transplantation and cause allograft rejections. The latter are systems of allelic alloantigens that can cause weak transplant rejection. .