serw-MX  [xml]  
 


    
 DeCS Categories

D06 Hormones, Hormone Substitutes, and Hormone Antagonists .
D06.472 Hormones .
D06.472.699 Peptide Hormones .
D06.472.699.587 Pancreatic Hormones .
D06.472.699.587.334 Islet Amyloid Polypeptide .
D08 Enzymes and Coenzymes .
D08.811 Enzymes .
D08.811.464 Ligases .
D08.811.464.938 Ubiquitin-Protein Ligase Complexes .
D08.811.464.938.750 Ubiquitin-Protein Ligases .
D08.811.464.938.750.210 Inhibitor of Apoptosis Proteins .
D08.811.464.938.750.210.250 Baculoviral IAP Repeat-Containing 3 Protein .
D12 Amino Acids, Peptides, and Proteins .
D12.644 Peptides .
D12.644.360 Intracellular Signaling Peptides and Proteins .
D12.644.360.075 Apoptosis Regulatory Proteins .
D12.644.360.075.437 Inhibitor of Apoptosis Proteins .
D12.644.360.075.437.250 Baculoviral IAP Repeat-Containing 3 Protein .
D12.644.548 Peptide Hormones .
D12.644.548.586 Pancreatic Hormones .
D12.644.548.586.234 Islet Amyloid Polypeptide .
D12.776 Proteins .
D12.776.049 Amyloid .
D12.776.049.407 Amyloidogenic Proteins .
D12.776.049.407.500 Islet Amyloid Polypeptide .
D12.776.094 Autophagy-Related Proteins .
D12.776.094.250 Autophagy-Related Protein 5 .
D12.776.476 Intracellular Signaling Peptides and Proteins .
D12.776.476.075 Apoptosis Regulatory Proteins .
D12.776.476.075.437 Inhibitor of Apoptosis Proteins .
D12.776.476.075.437.250 Baculoviral IAP Repeat-Containing 3 Protein .
G04 Cell Physiological Phenomena .
G04.146 Cell Death .
G04.146.160 Apoptosis .
 
 Terms
 Synonyms & Historicals
Documents
LILACS e MDL
 
Inhibitor of Apoptosis Proteins .
BIRC2 Protein .
Baculoviral IAP Repeat Containing Protein 2 .
Baculoviral IAP Repeat-Containing 2 Protein .
Baculoviral Inhibitor Of Apoptosis Repeat Proteins .
Cellular Inhibitor of Apoptosis 1 Protein .
IAP Protein (Apoptosis) .
IAP Repeat Containing Proteins .
IAP2 Protein .
Inhibitor of Apoptosis 2 Protein .
Inhibitor-Of-Apoptosis Protein .
c-IAP1 Protein .
cIAP1 Protein .
Apoptosis Proteins Inhibitor .
Baculoviral IAP Repeat Containing 2 Protein .
Inhibitor Of Apoptosis Protein .
A conserved class of proteins that control APOPTOSIS in both VERTEBRATES and INVERTEBRATES. IAP proteins interact with and inhibit CASPASES, and they function as ANTI-APOPTOTIC PROTEINS. The protein class is defined by an approximately 80-amino acid motif called the baculoviral inhibitor of apoptosis repeat; some members have ubiquitin-protein ligase activity. .
1.00
86402
 
Islet Amyloid Polypeptide .
Amlintide .
Amylin .
IAPP Precursor .
IAPP Protein .
Insulinoma Amyloid Polypeptide .
Insulinoma Amyloid Polypeptide Precursor .
Islet Amyloid Polypeptide Precursor .
Pancreatic Amylin .
Amylin, Pancreatic .
Amyloid Polypeptide, Insulinoma .
Amyloid Polypeptide, Islet .
Polypeptide, Insulinoma Amyloid .
Polypeptide, Islet Amyloid .
A pancreatic beta-cell hormone that is co-secreted with INSULIN. It displays an anorectic effect on nutrient metabolism by inhibiting gastric acid secretion, gastric emptying and postprandial GLUCAGON secretion. Islet amyloid polypeptide can fold into AMYLOID FIBRILS that have been found as a major constituent of pancreatic AMYLOID DEPOSITS. .
0.70
02179
 
Baculoviral IAP Repeat-Containing 3 Protein .
Apoptosis Inhibitor 2 .
BIRC3 Protein .
Baculoviral IAP Repeat Containing Protein 3 .
Cellular Inhibitor of Apoptosis-2 .
Hiap-1 Protein .
IAP1 Protein .
Inhibitor of Apoptosis 1 Protein .
Inhibitor of Apoptosis Protein 1 .
c-IAP2 Protein .
cIAP2 Protein .
Apoptosis-2 Cellular Inhibitor .
Baculoviral IAP Repeat Containing 3 Protein .
Cellular Inhibitor of Apoptosis 2 .
Hiap 1 Protein .
Inhibitor 2, Apoptosis .
A regulator of APOPTOSIS that functions as an E3 ubiquitin protein ligase. It contains three baculoviral IAP repeats in its N-terminal half, a CARD DOMAIN, and a RING finger domain at its C-terminus. It is highly expressed in fetal lung and kidney, and adult lymphoid tissues such as spleen, thymus, and peripheral blood lymphocytes. It functions in INFLAMMATION signaling, the INNATE IMMUNE RESPONSE, cell growth and proliferation, and metastasis of tumor cells. .
0.68
0263
 
Apoptosis Regulatory Proteins .
Apoptosis Inducing Proteins .
Apoptosis Inhibiting Proteins .
Death Factors (Apoptosis) .
Programmed Cell Death Proteins .
Survival Factors (Apoptosis) .
Regulatory Proteins, Apoptosis .
Anti-Apoptotic Proteins .
Pro-Apoptotic Proteins .
A large group of proteins that control APOPTOSIS. This family of proteins includes many ONCOGENE PROTEINS as well as a wide variety of classes of INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS such as CASPASES. .
0.66
2414602
 
Apoptosis .
Apoptosis, Extrinsic Pathway .
Apoptosis, Intrinsic Pathway .
Programmed Cell Death, Type I .
Apoptoses, Extrinsic Pathway .
Apoptoses, Intrinsic Pathway .
Extrinsic Pathway Apoptoses .
Extrinsic Pathway Apoptosis .
Intrinsic Pathway Apoptoses .
Intrinsic Pathway Apoptosis .
Cell Death, Programmed .
One of the mechanisms by which CELL DEATH occurs (compare with NECROSIS and AUTOPHAGOCYTOSIS). Apoptosis is the mechanism responsible for the physiological deletion of cells and appears to be intrinsically programmed. It is characterized by distinctive morphologic changes in the nucleus and cytoplasm, chromatin cleavage at regularly spaced sites, and the endonucleolytic cleavage of genomic DNA; (DNA FRAGMENTATION); at internucleosomal sites. This mode of cell death serves as a balance to mitosis in regulating the size of animal tissues and in mediating pathologic processes associated with tumor growth. .
0.66
 
Autophagy-Related Protein 5 .
ATG-5 Protein .
ATG5 Protein .
Apoptosis-Specific Protein .
Autophagy Protein-5 .
Autophagy-Related 5 Protein .
ATG 5 Protein .
Apoptosis Specific Protein .
Autophagy Protein 5 .
Autophagy Related 5 Protein .
Autophagy Related Protein 5 .
An autophagy-related protein that functions in AUTOPHAGOSOME biogenesis. It is conjugated to the ATG12 PROTEIN via a process that is similar to UBIQUITINATION and involves the ATG7 PROTEIN and ATG10 enzyme. The ATG12-ATG5 conjugate acts as an E3 UBIQUITIN LIGASE-like enzyme and is required for the localization of ATG8 PROTEINS to AUTOPHAGOSOME vesicle membranes and modification of membrane lipids. .
0.62
0836