serw-MX  [xml]  
 


    
 DeCS Categories

D02 Organic Chemicals .
D02.455 Hydrocarbons .
D02.455.849 Terpenes .
D02.455.849.291 Diterpenes .
D02.455.849.291.075 Aphidicolin .
D03 Heterocyclic Compounds .
D03.383 Heterocyclic Compounds, 1-Ring .
D03.383.725 Pyridines .
D03.383.725.150 Carbolines .
D03.383.725.150.500 Tadalafil .
D03.633 Heterocyclic Compounds, Fused-Ring .
D03.633.100 Heterocyclic Compounds, 2-Ring .
D03.633.100.473 Indoles .
D03.633.100.473.155 Carbolines .
D03.633.100.473.155.500 Tadalafil .
D03.633.300 Heterocyclic Compounds, 3-Ring .
D03.633.300.154 Carbolines .
D03.633.300.154.672 Tadalafil .
D12 Amino Acids, Peptides, and Proteins .
D12.776 Proteins .
D12.776.124 Blood Proteins .
D12.776.124.486 Immunoproteins .
D12.776.124.486.274 Complement System Proteins .
D12.776.124.486.274.250 Complement C3 .
D12.776.124.486.274.250.260 Complement C3b .
 
 Terms
 Synonyms & Historicals
Documents
LILACS e MDL
 
Tadalafil .
Cialis .
IC 351 .
IC-351 .
IC351 .
351, IC .
A carboline derivative and PHOSPHODIESTERASE 5 INHIBITOR that is used primarily to treat ERECTILE DYSFUNCTION; BENIGN PROSTATIC HYPERPLASIA and PRIMARY PULMONARY HYPERTENSION. .
1.00
121154
 
Complement C3b .
C3b Complement .
C3bi 12364 .
Complement 3b .
Complement Component 3b .
Inactivated C3b .
iC3b 12364 .
C3b, Complement .
C3b, Inactivated .
Complement, C3b .
Component 3b, Complement .
Complement 3b .
The larger fragment generated from the cleavage of COMPLEMENT C3 by C3 CONVERTASE. It is a constituent of the ALTERNATIVE PATHWAY C3 CONVERTASE (C3bBb), and COMPLEMENT C5 CONVERTASES in both the classical (C4b2a3b) and the alternative (C3bBb3b) pathway. C3b participates in IMMUNE ADHERENCE REACTION and enhances PHAGOCYTOSIS. It can be inactivated (iC3b) or cleaved by various proteases to yield fragments such as COMPLEMENT C3C; COMPLEMENT C3D; C3e; C3f; and C3g. .
0.48
71889
 
Aphidicolin .
Aphidicolin, (3-S-(3alpha,4beta,4abeta,6aalpha,8alpha,9alpha,11aalpha,11balpha))-Isomer .
ICI-69653 .
NSC-234714 .
NSC-351140 .
ICI 69653 .
ICI69653 .
NSC 234714 .
NSC 351140 .
NSC234714 .
NSC351140 .
An antiviral antibiotic produced by Cephalosporium aphidicola and other fungi. It inhibits the growth of eukaryotic cells and certain animal viruses by selectively inhibiting the cellular replication of DNA polymerase II or the viral-induced DNA polymerases. The drug may be useful for controlling excessive cell proliferation in patients with cancer, psoriasis or other dermatitis with little or no adverse effect upon non-multiplying cells. .
0.30
41568