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 DeCS Categories

D12 Amino Acids, Peptides, and Proteins .
D12.776 Proteins .
D12.776.124 Blood Proteins .
D12.776.124.486 Immunoproteins .
D12.776.124.486.485 Immunoglobulins .
D12.776.124.486.485.114 Antibodies .
D12.776.124.486.485.114.619 Immunoglobulin Isotypes .
D12.776.124.486.485.114.619.026 Immunoglobulin A .
D12.776.124.486.485.114.619.026.515 Immunoglobulin alpha-Chains .
D12.776.124.486.485.114.619.393 Immunoglobulin G .
D12.776.124.486.485.114.619.393.536 Immunoglobulins, Intravenous .
D12.776.124.486.485.114.632 Immunoglobulins, Intravenous .
D12.776.124.486.485.705 Immunoglobulin Subunits .
D12.776.124.486.485.705.500 Immunoglobulin Heavy Chains .
D12.776.124.486.485.705.500.350 Immunoglobulin alpha-Chains .
D12.776.124.790 Serum Globulins .
D12.776.124.790.651 Immunoglobulins .
D12.776.124.790.651.114 Antibodies .
D12.776.124.790.651.114.619 Immunoglobulin Isotypes .
D12.776.124.790.651.114.619.026 Immunoglobulin A .
D12.776.124.790.651.114.619.026.515 Immunoglobulin alpha-Chains .
D12.776.124.790.651.114.632 Immunoglobulins, Intravenous .
D12.776.124.790.651.705 Immunoglobulin Subunits .
D12.776.124.790.651.705.500 Immunoglobulin Heavy Chains .
D12.776.124.790.651.705.500.350 Immunoglobulin alpha-Chains .
D12.776.377 Globulins .
D12.776.377.715 Serum Globulins .
D12.776.377.715.548 Immunoglobulins .
D12.776.377.715.548.114 Antibodies .
D12.776.377.715.548.114.619 Immunoglobulin Isotypes .
D12.776.377.715.548.114.619.026 Immunoglobulin A .
D12.776.377.715.548.114.619.026.515 Immunoglobulin alpha-Chains .
D12.776.377.715.548.114.632 Immunoglobulins, Intravenous .
D12.776.377.715.548.705 Immunoglobulin Subunits .
D12.776.377.715.548.705.500 Immunoglobulin Heavy Chains .
D12.776.377.715.548.705.500.350 Immunoglobulin alpha-Chains .
G05 Genetic Phenomena .
G05.360 Genetic Structures .
G05.360.340 Genome .
G05.360.340.024 Genome Components .
G05.360.340.024.340 Genes .
G05.360.340.024.340.335 Genes, Immunoglobulin .
G12 Immune System Phenomena .
G12.500 Immunogenetic Phenomena .
G12.500.299 Genes, Immunoglobulin .
 
 Terms
 Synonyms & Historicals
Documents
LILACS e MDL
 
Immunoglobulins .
Immunoglobulin .
Globulins, Immune .
Immune Globulins .
Multi-subunit proteins which function in IMMUNITY. They are produced by B LYMPHOCYTES from the IMMUNOGLOBULIN GENES. They are comprised of two heavy (IMMUNOGLOBULIN HEAVY CHAINS) and two light chains (IMMUNOGLOBULIN LIGHT CHAINS) with additional ancillary polypeptide chains depending on their isoforms. The variety of isoforms include monomeric or polymeric forms, and transmembrane forms (B-CELL ANTIGEN RECEPTORS) or secreted forms (ANTIBODIES). They are divided by the amino acid sequence of their heavy chains into five classes (IMMUNOGLOBULIN A; IMMUNOGLOBULIN D; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M) and various subclasses. .
1.00
60440862
 
Immunoglobulin A .
IgA1 12281 .
IgA2 12281 .
IgA 12281 .
Represents 15-20% of the human serum immunoglobulins, mostly as the 4-chain polymer in humans or dimer in other mammals. Secretory IgA (IMMUNOGLOBULIN A, SECRETORY) is the main immunoglobulin in secretions. .
0.89
36731452
 
Immunoglobulins, Intravenous .
Alphaglobin .
Endobulin .
Flebogamma DIF .
Gamimmune .
Gamimmune N .
Gamimune .
Gamimune N .
Gammagard .
Gammonativ .
Gamunex .
Globulin-N .
IV Immunoglobulins .
Immune Globulin Intravenous (Human) .
Immune Globulin, Intravenous .
Immunoglobulins, Intravenous, Human .
Intraglobin .
Intraglobin F .
Intravenous IG .
Intravenous Immunoglobulins, Human .
Iveegam .
Modified Immune Globulin (Anti-Echovirus Antibody) .
Privigen .
Sandoglobulin .
Venimmune .
Venoglobulin .
Venoglobulin-I .
Globulin N .
GlobulinN .
Human Intravenous Immunoglobulins .
Immunoglobulins, Human Intravenous .
Immunoglobulins, IV .
Intravenous Immune Globulin .
Venoglobulin I .
VenoglobulinI .
Antibodies, Intravenous .
Intravenous Antibodies .
Intravenous Immunoglobulins .
IVIG 18193 .
Immunoglobulin preparations used in intravenous infusion, containing primarily IMMUNOGLOBULIN G. They are used to treat a variety of diseases associated with decreased or abnormal immunoglobulin levels including pediatric AIDS; primary HYPERGAMMAGLOBULINEMIA; SCID; CYTOMEGALOVIRUS infections in transplant recipients, LYMPHOCYTIC LEUKEMIA, CHRONIC; Kawasaki syndrome, infection in neonates, and IDIOPATHIC THROMBOCYTOPENIC PURPURA. .
0.85
13311494
 
Immunoglobulin Subunits .
Ig Polypeptide Chains .
Ig Subunit .
Ig Subunits .
Immunoglobulin Chains .
Immunoglobulin Polypeptide Chains .
Subunit, Ig .
Subunits, Ig .
The PROTEIN SUBUNITS of the multimeric IMMUNOGLOBULIN proteins, such as IGA; IGD; IGE; IGG; and IGM. Included are the heavy and light chains which contain the specific ANTIGEN binding domains, as well as the accessory proteins that are part of the the secreted forms of IGM and IGA; (SECRETORY IGA). .
0.85
037
 
Immunoglobulin alpha-Chains .
Immunoglobulin alpha-Chain .
alpha-Chain Immunoglobulins .
alpha-Immunoglobulin Heavy Chain .
alpha-Immunoglobulin Heavy Chains .
Heavy Chain, alpha-Immunoglobulin .
Heavy Chains, alpha-Immunoglobulin .
Immunoglobulin alpha Chains .
Immunoglobulins, alpha Chain .
alpha Chain Immunoglobulins .
alpha Immunoglobulin Heavy Chain .
alpha Immunoglobulin Heavy Chains .
alpha-Chains, Immunoglobulin .
Immunoglobulins, alpha-Chain .
Immunoglobulins, alpha Chain .
alpha Immunoglobulins .
The class of heavy chains found in IMMUNOGLOBULIN A. They have a molecular weight of approximately 58 kDa and contain about 470 amino acid residues arranged in four domains and an oligosaccharide component bound covalently to their Fc fragment constant region. .
0.85
16565
 
Genes, Immunoglobulin .
Gene, Ig .
Gene, Immunoglobulin .
Ig Gene .
Ig Genes .
Immunoglobulin Gene .
Genes, Ig .
Immunoglobulin Genes .
Genes encoding the different subunits of the IMMUNOGLOBULINS, for example the IMMUNOGLOBULIN LIGHT CHAIN GENES and the IMMUNOGLOBULIN HEAVY CHAIN GENES. The heavy and light immunoglobulin genes are present as gene segments in the germline cells. The completed genes are created when the segments are shuffled and assembled (B-LYMPHOCYTE GENE REARRANGEMENT) during B-LYMPHOCYTE maturation. The gene segments of the human light and heavy chain germline genes are symbolized V (variable), J (joining) and C (constant). The heavy chain germline genes have an additional segment D (diversity). .
0.85
116505