serw-MX  [xml]  

 DeCS Categories

D02 Organic Chemicals .
D02.540 Lactones .
D02.540.505 Macrolides .
D02.540.505.760 Sirolimus .
D09 Carbohydrates .
D09.400 Glycoconjugates .
D09.400.500 Lipopolysaccharides .
D09.698 Polysaccharides .
D09.698.718 Polysaccharides, Bacterial .
D09.698.718.450 Lipopolysaccharides .
D09.698.718.450.500 Lipid A .
D10 Lipids .
D10.494 Lipopolysaccharides .
D10.494.500 Lipid A .
D23 Biological Factors .
D23.050 Antigens .
D23.050.161 Antigens, Bacterial .
D23.050.161.616 Polysaccharides, Bacterial .
D23.050.161.616.525 Lipopolysaccharides .
D23.050.161.616.525.500 Lipid A .
D23.946 Toxins, Biological .
D23.946.123 Bacterial Toxins .
D23.946.123.329 Endotoxins .
D23.946.123.329.500 Lipopolysaccharides .
D23.946.123.329.500.500 Lipid A .
D27 Chemical Actions and Uses .
D27.505 Pharmacologic Actions .
D27.505.519 Molecular Mechanisms of Pharmacological Action .
D27.505.519.374 Enzyme Activators .
D27.505.519.374.600 Lipoprotein Lipase Activators .
D27.505.954 Therapeutic Uses .
D27.505.954.557 Lipid Regulating Agents .
D27.505.954.557.500 Hypolipidemic Agents .
D27.505.954.557.500.601 Lipotropic Agents .
D27.505.954.557.500.601.500 Lipoprotein Lipase Activators .
 Synonyms & Historicals
Lipid A .
Lipid A is the biologically active component of lipopolysaccharides. It shows strong endotoxic activity and exhibits immunogenic properties. .
Lipopolysaccharides .
Lipoglycans .
Lipid-containing polysaccharides which are endotoxins and important group-specific antigens. They are often derived from the cell wall of gram-negative bacteria and induce immunoglobulin secretion. The lipopolysaccharide molecule consists of three parts: LIPID A, core polysaccharide, and O-specific chains (O ANTIGENS). When derived from Escherichia coli, lipopolysaccharides serve as polyclonal B-cell mitogens commonly used in laboratory immunology. (From Dorland, 28th ed) .
Lipoprotein Lipase Activators .
Activators, Lipoprotein Lipase .
Lipase Activators, Lipoprotein .
Lipoprotein Lipase Activating Agents .
Compounds that increase the enzymatic activity of LIPOPROTEIN LIPASE. Lipoprotein lipase activators have a potential role in the treatment of OBESITY by increasing LIPID METABOLISM. Note that substances that increase the synthesis of lipoprotein lipase are not included here. .
Lipids .
Lipids and Antilipemic Agents .
A generic term for fats and lipoids, the alcohol-ether-soluble constituents of protoplasm, which are insoluble in water. They comprise the fats, fatty oils, essential oils, waxes, phospholipids, glycolipids, sulfolipids, aminolipids, chromolipids (lipochromes), and fatty acids. (Grant & Hackh's Chemical Dictionary, 5th ed) .
Sirolimus .
AY 22-989 .
I-2190A .
Rapamune .
AY 22 989 .
AY 22989 .
I 2190A .
I2190A .
Rapamycin .
A macrolide compound obtained from Streptomyces hygroscopicus that acts by selectively blocking the transcriptional activation of cytokines thereby inhibiting cytokine production. It is bioactive only when bound to IMMUNOPHILINS. Sirolimus is a potent immunosuppressant and possesses both antifungal and antineoplastic properties. .