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 DeCS Categories

C15 Hemic and Lymphatic Diseases .
C15.378 Hematologic Diseases .
C15.378.619 Methemoglobinemia .
C15.378.896 Sulfhemoglobinemia .
D08 Enzymes and Coenzymes .
D08.811 Enzymes .
D08.811.682 Oxidoreductases .
D08.811.682.608 NADH, NADPH Oxidoreductases .
D08.811.682.608.191 Cytochrome Reductases .
D08.811.682.608.191.237 Cytochrome-B(5) Reductase .
D12 Amino Acids, Peptides, and Proteins .
D12.776 Proteins .
D12.776.124 Blood Proteins .
D12.776.124.400 Hemoglobins .
D12.776.124.400.599 Methemoglobin .
D12.776.331 Flavoproteins .
D12.776.331.186 Cytochrome-B(5) Reductase .
D12.776.422 Hemeproteins .
D12.776.422.316 Globins .
D12.776.422.316.762 Hemoglobins .
D12.776.422.316.762.571 Methemoglobin .
 
 Terms
 Synonyms & Historicals
Documents
LILACS e MDL
 
Methemoglobinemia .
Methemoglobinemias .
The presence of methemoglobin in the blood, resulting in cyanosis. A small amount of methemoglobin is present in the blood normally, but injury or toxic agents convert a larger proportion of hemoglobin into methemoglobin, which does not function reversibly as an oxygen carrier. Methemoglobinemia may be due to a defect in the enzyme NADH methemoglobin reductase (an autosomal recessive trait) or to an abnormality in hemoglobin M (an autosomal dominant trait). (Dorland, 27th ed) .
1.00
622465
 
Methemoglobin .
Ferrihemoglobin .
0.86
223490
 
Cytochrome-B(5) Reductase .
Methemoglobin Reductase .
NADH Cytochrome B5 Reductase .
NADH Methemoglobin Reductase .
NADH-Cytochrome B5 Reductase .
NADH-Ferrihemoglobin Reductase .
B5 Reductase, NADH-Cytochrome .
Methemoglobin Reductase, NADH .
NADH Ferrihemoglobin Reductase .
Reductase, Methemoglobin .
Reductase, NADH Methemoglobin .
Reductase, NADH-Ferrihemoglobin .
METHEMOGLOBIN REDUCTASE .
A FLAVOPROTEIN oxidoreductase that occurs both as a soluble enzyme and a membrane-bound enzyme due to ALTERNATIVE SPLICING of a single mRNA. The soluble form is present mainly in ERYTHROCYTES and is involved in the reduction of METHEMOGLOBIN. The membrane-bound form of the enzyme is found primarily in the ENDOPLASMIC RETICULUM and outer mitochondrial membrane, where it participates in the desaturation of FATTY ACIDS; CHOLESTEROL biosynthesis and drug metabolism. A deficiency in the enzyme can result in METHEMOGLOBINEMIA. .
0.65
3708
 
Sulfhemoglobinemia .
Sulfhemoglobinemias .
A morbid condition due to the presence of sulfmethemoglobin in the blood. It is marked by persistent cyanosis, but the blood count does not reveal any special abnormality in the blood. It is thought to be caused by the action of hydrogen sulfide absorbed from the intestine. (Stedman, 25th ed) .
0.65
074
 
Hemoglobins .
Eryhem .
Ferrous Hemoglobin .
Hemoglobin .
Hemoglobin, Ferrous .
The oxygen-carrying proteins of ERYTHROCYTES. They are found in all vertebrates and some invertebrates. The number of globin subunits in the hemoglobin quaternary structure differs between species. Structures range from monomeric to a variety of multimeric arrangements. .
0.59
76958519