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 DeCS Categories

D08 Enzymes and Coenzymes .
D08.244 Cytochromes .
D08.244.453 Cytochrome P-450 Enzyme System .
D08.811 Enzymes .
D08.811.682 Oxidoreductases .
D08.811.682.690 Oxygenases .
D08.811.682.690.708 Mixed Function Oxygenases .
D08.811.682.690.708.170 Cytochrome P-450 Enzyme System .
D12 Amino Acids, Peptides, and Proteins .
D12.776 Proteins .
D12.776.422 Hemeproteins .
D12.776.422.220 Cytochromes .
D12.776.422.220.453 Cytochrome P-450 Enzyme System .
D27 Chemical Actions and Uses .
D27.505 Pharmacologic Actions .
D27.505.389 Metabolic Side Effects of Drugs and Substances .
D27.505.389.249 Cytochrome P-450 Enzyme Inducers .
D27.505.389.500 Cytochrome P-450 Enzyme Inhibitors .
D27.505.519 Molecular Mechanisms of Pharmacological Action .
D27.505.519.349 Cytochrome P-450 Enzyme Inducers .
D27.505.519.389 Enzyme Inhibitors .
D27.505.519.389.335 Cytochrome P-450 Enzyme Inhibitors .
 
 Terms
 Synonyms & Historicals
Documents
LILACS e MDL
 
Cytochrome P-450 Enzyme System .
CYP450 Family .
CYP450 Superfamily .
Cytochrome P-450 Enzymes .
Cytochrome P-450 Families .
Cytochrome P-450 Monooxygenase .
Cytochrome P-450 Oxygenase .
Cytochrome P-450 Superfamily .
Cytochrome P450 .
Cytochrome P450 Superfamily .
Cytochrome p450 Families .
P-450 Enzymes .
P450 Enzymes .
Cytochrome P 450 .
Cytochrome P 450 Dependent Monooxygenase .
Cytochrome P 450 Enzyme System .
Cytochrome P 450 Enzymes .
Cytochrome P 450 Families .
Cytochrome P 450 Monooxygenase .
Cytochrome P 450 Oxygenase .
Cytochrome P 450 Superfamily .
Enzymes, Cytochrome P-450 .
Enzymes, P-450 .
Enzymes, P450 .
Monooxygenase, Cytochrome P-450 .
Monooxygenase, Cytochrome P-450-Dependent .
P 450 Enzymes .
P-450 Enzymes, Cytochrome .
Superfamily, CYP450 .
Superfamily, Cytochrome P-450 .
Superfamily, Cytochrome P450 .
Cytochrome P-450 .
Cytochrome P-450-Dependent Monooxygenase .
A superfamily of hundreds of closely related HEMEPROTEINS found throughout the phylogenetic spectrum, from animals, plants, fungi, to bacteria. They include numerous complex monooxygenases (MIXED FUNCTION OXYGENASES). In animals, these P-450 enzymes serve two major functions: (1) biosynthesis of steroids, fatty acids, and bile acids; (2) metabolism of endogenous and a wide variety of exogenous substrates, such as toxins and drugs (BIOTRANSFORMATION). They are classified, according to their sequence similarities rather than functions, into CYP gene families (>40% homology) and subfamilies (>59% homology). For example, enzymes from the CYP1, CYP2, and CYP3 gene families are responsible for most drug metabolism. .
1.00
4139776
 
Cytochrome P-450 Enzyme Inducers .
Cytochrome P-450 Inducers .
Cytochrome P-450 Monooxygenase Inducers .
Cytochrome P-450 Oxygenase Inducers .
Cytochrome P-450-Dependent Monooxygenase Inducers .
P-450 Enzyme Inducers .
Cytochrome P 450 Dependent Monooxygenase Inducers .
Cytochrome P 450 Enzyme Inducers .
Cytochrome P 450 Inducers .
Cytochrome P 450 Monooxygenase Inducers .
Cytochrome P 450 Oxygenase Inducers .
Enzyme Inducers, P-450 .
Inducers, P-450 Enzyme .
P 450 Enzyme Inducers .
Drugs and compounds that induce the synthesis of CYTOCHROME P-450 ENZYMES. .
0.90
061
 
Cytochrome P-450 Enzyme Inhibitors .
Cytochrome P-450 Inhibitors .
Cytochrome P-450 Monooxygenase Inhibitors .
Cytochrome P-450 Oxygenase Inhibitors .
Cytochrome P-450-Dependent Monooxygenase Inhibitors .
P-450 Enzyme Inhibitors .
P450 Enzyme Inhibitors .
Cytochrome P 450 Dependent Monooxygenase Inhibitors .
Cytochrome P 450 Enzyme Inhibitors .
Cytochrome P 450 Inhibitors .
Cytochrome P 450 Monooxygenase Inhibitors .
Cytochrome P 450 Oxygenase Inhibitors .
Enzyme Inhibitors, P-450 .
Enzyme Inhibitors, P450 .
Inhibitors, Cytochrome P-450 .
Inhibitors, P-450 Enzyme .
Inhibitors, P450 Enzyme .
P 450 Enzyme Inhibitors .
P-450 Inhibitors, Cytochrome .
Drugs and compounds which inhibit or antagonize the biosynthesis or actions of CYTOCHROME P-450 ENZYMES. .
0.87
05278