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 DeCS Categories

D08 Enzymes and Coenzymes .
D08.244 Cytochromes .
D08.244.453 Cytochrome P-450 Enzyme System .
D08.244.453.005 Aryl Hydrocarbon Hydroxylases .
D08.244.453.005.600 Cytochrome P-450 CYP2D6 .
D08.244.453.491 Cytochrome P450 Family 2 .
D08.244.453.491.372 Cytochrome P-450 CYP2D6 .
D08.244.453.491.500 Limonene Hydroxylases .
D08.244.453.915 Steroid Hydroxylases .
D08.811 Enzymes .
D08.811.682 Oxidoreductases .
D08.811.682.690 Oxygenases .
D08.811.682.690.708 Mixed Function Oxygenases .
D08.811.682.690.708.125 Catechol Oxidase .
D08.811.682.690.708.125.500 Monophenol Monooxygenase .
D08.811.682.690.708.170 Cytochrome P-450 Enzyme System .
D08.811.682.690.708.170.010 Aryl Hydrocarbon Hydroxylases .
D08.811.682.690.708.170.010.600 Cytochrome P-450 CYP2D6 .
D08.811.682.690.708.170.450 Cytochrome P450 Family 2 .
D08.811.682.690.708.170.450.368 Cytochrome P-450 CYP2D6 .
D08.811.682.690.708.170.450.500 Limonene Hydroxylases .
D08.811.682.690.708.170.915 Steroid Hydroxylases .
D12 Amino Acids, Peptides, and Proteins .
D12.776 Proteins .
D12.776.422 Hemeproteins .
D12.776.422.220 Cytochromes .
D12.776.422.220.453 Cytochrome P-450 Enzyme System .
D12.776.422.220.453.010 Aryl Hydrocarbon Hydroxylases .
D12.776.422.220.453.010.600 Cytochrome P-450 CYP2D6 .
D12.776.422.220.453.491 Cytochrome P450 Family 2 .
D12.776.422.220.453.491.368 Cytochrome P-450 CYP2D6 .
D12.776.422.220.453.491.500 Limonene Hydroxylases .
D12.776.422.220.453.915 Steroid Hydroxylases .
 
 Terms
 Synonyms & Historicals
Documents
LILACS e MDL
 
Mixed Function Oxygenases .
Mixed Function Oxidases .
Oxidases, Mixed Function .
Oxygenases, Mixed Function .
Hydroxylases .
Monooxygenases .
MIXED FUNCTION OXIDASES .
Widely distributed enzymes that carry out oxidation-reduction reactions in which one atom of the oxygen molecule is incorporated into the organic substrate; the other oxygen atom is reduced and combined with hydrogen ions to form water. They are also known as monooxygenases or hydroxylases. These reactions require two substrates as reductants for each of the two oxygen atoms. There are different classes of monooxygenases depending on the type of hydrogen-providing cosubstrate (COENZYMES) required in the mixed-function oxidation. .
1.00
3016729
 
Monophenol Monooxygenase .
Cresolase .
Phenol Oxidase .
Phenoloxidase A .
Phenoloxidase B .
Monooxygenase, Monophenol .
Oxidase, Dopa .
Oxidase, Phenol .
Dopa Oxidase .
Phenoloxidase .
Tyrosinase .
An enzyme of the oxidoreductase class that catalyzes the reaction between L-tyrosine, L-dopa, and oxygen to yield L-dopa, dopaquinone, and water. It is a copper protein that acts also on catechols, catalyzing some of the same reactions as CATECHOL OXIDASE. EC 1.14.18.1. .
0.83
286223
 
Steroid Hydroxylases .
Hydroxylases, Steroid .
Monooxygenases, Steroid .
Steroid Monooxygenases .
Cytochrome P-450 monooxygenases (MIXED FUNCTION OXYGENASES) that are important in steroid biosynthesis and metabolism. .
0.81
75233
 
Limonene Hydroxylases .
(R)-Limonene 6-Monooxygenase .
(S)-Limonene 6-Monooxygenase .
(S)-Limonene 7-Monooxygenase .
Limonene Monooxygenases .
Hydroxylases, Limonene .
Monooxygenases, Limonene .
Members of the P-450 enzyme family that take part in the hydroxylation of limonene. .
0.77
01
 
Aryl Hydrocarbon Hydroxylases .
Microsomal Monooxygenases .
Xenobiotic Monooxygenases .
Hydroxylases, Aryl Hydrocarbon .
Monooxygenases, Microsomal .
Monooxygenases, Xenobiotic .
A large group of cytochrome P-450 (heme-thiolate) monooxygenases that complex with NAD(P)H-FLAVIN OXIDOREDUCTASE in numerous mixed-function oxidations of aromatic compounds. They catalyze hydroxylation of a broad spectrum of substrates and are important in the metabolism of steroids, drugs, and toxins such as PHENOBARBITAL, carcinogens, and insecticides. .
0.77
1411092
 
Cytochrome P-450 CYP2D6 .
CYP 2D6 .
Cytochrome P450 2D6 .
Debrisoquine 4-Monooxygenase .
Imipramine 2-Hydroxylase .
Sparteine Monooxygenase .
2-Hydroxylase, Imipramine .
4-Hydroxylase, Debrisoquine .
4-Monooxygenase, Debrisoquine .
CYP2D6, Cytochrome P-450 .
Cytochrome P 450 CYP2D6 .
Debrisoquine 4 Hydroxylase .
Debrisoquine 4 Monooxygenase .
Hydroxylase, Debrisoquine .
Imipramine 2 Hydroxylase .
Monooxygenase, Sparteine .
P-450 CYP2D6, Cytochrome .
P450 2D6, Cytochrome .
CYP2D6 .
Debrisoquine Hydroxylase .
Debrisoquine 4-Hydroxylase .
A cytochrome P450 enzyme that catalyzes the hydroxylation of many drugs and environmental chemicals, such as DEBRISOQUINE; ADRENERGIC RECEPTOR ANTAGONISTS; and TRICYCLIC ANTIDEPRESSANTS. This enzyme is deficient in up to 10 percent of the Caucasian population. .
0.75
43825