Muscle Fibers, Skeletal. Skeletal Muscle Fibers . Fiber, Skeletal Muscle . Fibers, Skeletal Muscle . Muscle Fiber, Skeletal . Myocyte, Skeletal . Myotube . Skeletal Muscle Fiber . Skeletal Myocyte . Myocytes, Skeletal . Myotubes . Skeletal Myocytes . Muscle Fibers . Large, multinucleate single cells, either cylindrical or prismatic in shape, that form the basic unit of SKELETAL MUSCLE. They consist of MYOFIBRILS enclosed within and attached to the SARCOLEMMA. They are derived from the fusion of skeletal myoblasts (MYOBLASTS, SKELETAL) into a syncytium, followed by differentiation. . 0.80