Meningomyelocele. Acquired Meningomyelocele . Myelomeningocele, Acquired . Acquired Meningomyeloceles . Acquired Myelomeningocele . Acquired Myelomeningoceles . Meningomyelocele, Acquired . Meningomyeloceles . Meningomyeloceles, Acquired . Myeloceles . Myelomeningoceles . Myelomeningoceles, Acquired . Myelocele . Myelomeningocele . Congenital, or rarely acquired, herniation of meningeal and spinal cord tissue through a bony defect in the vertebral column. The majority of these defects occur in the lumbosacral region. Clinical features include PARAPLEGIA, loss of sensation in the lower body, and incontinence. This condition may be associated with the ARNOLD-CHIARI MALFORMATION and HYDROCEPHALUS. (From Joynt, Clinical Neurology, 1992, Ch55, pp35-6) . 1.00
Busulfan. Busulfan Wellcome . Busulfex . Glyzophrol . Myelosan . Mylecytan . Myleran . Myléran . n-Butane-1,3-di(methylsulfonate) . Wellcome, Busulfan . Busulphan . An alkylating agent having a selective immunosuppressive effect on BONE MARROW. It has been used in the palliative treatment of chronic myeloid leukemia (MYELOID LEUKEMIA, CHRONIC), but although symptomatic relief is provided, no permanent remission is brought about. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), busulfan is listed as a known carcinogen. . 0.67
Myelin Sheath. Myelin Sheaths . Sheath, Myelin . Sheaths, Myelin . Myelin . The lipid-rich sheath surrounding AXONS in both the CENTRAL NERVOUS SYSTEMS and PERIPHERAL NERVOUS SYSTEM. The myelin sheath is an electrical insulator and allows faster and more energetically efficient conduction of impulses. The sheath is formed by the cell membranes of glial cells (SCHWANN CELLS in the peripheral and OLIGODENDROGLIA in the central nervous system). Deterioration of the sheath in DEMYELINATING DISEASES is a serious clinical problem. . 0.67
