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 DeCS Categories

D02 Organic Chemicals .
D02.033 Alcohols .
D02.033.260 Chlorohydrins .
D02.033.260.350 Ethylene Chlorohydrin .
D02.033.375 Ethanol .
D02.033.375.310 Ethylene Chlorohydrin .
D02.092 Amines .
D02.092.146 Aniline Compounds .
D02.092.146.500 Methylenebis(chloroaniline) .
D02.455 Hydrocarbons .
D02.455.426 Hydrocarbons, Cyclic .
D02.455.426.559 Hydrocarbons, Aromatic .
D02.455.426.559.389 Benzene Derivatives .
D02.455.426.559.389.115 Benzhydryl Compounds .
D02.455.426.559.389.115.500 Methylenebis(chloroaniline) .
D02.455.526 Hydrocarbons, Halogenated .
D02.455.526.728 Mustard Compounds .
D02.455.526.728.650 Nitrogen Mustard Compounds .
D02.455.526.728.650.050 Aniline Mustard .
D02.455.526.728.650.156 Chlorambucil .
D02.455.526.728.650.529 Mechlorethamine .
D02.455.526.728.650.594 Melphalan .
D02.654 Nitroso Compounds .
D02.654.692 Nitrosourea Compounds .
D02.654.692.247 Carmustine .
D02.948 Urea 11093 .
D02.948.594 Nitrosourea Compounds .
D02.948.594.247 Carmustine .
D12 Amino Acids, Peptides, and Proteins .
D12.125 Amino Acids .
D12.125.072 Amino Acids, Cyclic .
D12.125.072.050 Amino Acids, Aromatic .
D12.125.072.050.685 Phenylalanine .
D12.125.072.050.685.500 Melphalan .
 
 Terms
 Synonyms & Historicals
Documents
LILACS e MDL
 
Aniline Mustard .
Lymphochin .
Lymphocin .
Lymphoquin .
N,N-Di(2-Chloroethyl)aniline .
N,N-bis(2-chloroethyl)aniline .
N,N-bis-(2-chloroethyl)aniline .
Mustard, Aniline .
Alkylating anti-neoplastic agent. .
1.00
587
 
Carmustine .
1,3-Bis(2-Chloroethyl)-1-Nitrosourea .
BiCNU .
FIVB 1834 .
N,N'-Bis(2-Chloroethyl)-N-Nitrosourea .
Nitrumon .
BCNU 1834 .
A cell-cycle phase nonspecific alkylating antineoplastic agent. It is used in the treatment of brain tumors and various other malignant neoplasms. (From Martindale, The Extra Pharmacopoeia, 30th ed, p462) This substance may reasonably be anticipated to be a carcinogen according to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (From Merck Index, 11th ed) .
0.80
133818
 
Mechlorethamine .
Bis(2-chloroethyl)methylamine .
Caryolysine .
Cloramin .
Embichin .
Mechlorethamine Hydrochloride .
Mechlorethamine Hydrochloride N-Oxide .
Mechlorethamine N-Oxide .
Methylchlorethamine .
Mitomen .
Mustargen .
NSC-10107 .
NSC-762 .
Nitrogranulogen .
Nitromin .
Hydrochloride N-Oxide, Mechlorethamine .
Hydrochloride, Mechlorethamine .
Mechlorethamine Hydrochloride N Oxide .
Mechlorethamine N Oxide .
N-Oxide, Mechlorethamine Hydrochloride .
N-Oxide, Nitrogen Mustard .
NSC 10107 .
NSC 762 .
NSC10107 .
NSC762 .
Nitrogen Mustard N Oxide .
Chlorethazine .
Chlormethine .
Mechlorethamine Oxide .
Mustine .
Nitrogen Mustard .
Nitrogen Mustard N-Oxide .
A biologic alkylating agent that exerts its cytotoxic effects by forming DNA ADDUCTS and DNA interstrand crosslinks, thereby inhibiting rapidly proliferating cells. The hydrochloride is an antineoplastic agent used to treat HODGKIN DISEASE and LYMPHOMA. .
0.66
123102
 
Melphalan .
4-(Bis(2-chloroethyl)amino)phenylalanine .
Alkeran .
L-PAM .
Mustard, Phenylalanine .
Medphalan .
Merphalan .
Phenylalanine Mustard .
Sarcolysine .
Sarkolysin .
An alkylating nitrogen mustard that is used as an antineoplastic in the form of the levo isomer - MELPHALAN, the racemic mixture - MERPHALAN, and the dextro isomer - MEDPHALAN; toxic to bone marrow, but little vesicant action; potential carcinogen. .
0.56
266876
 
Chlorambucil .
4-(Bis(2-chloroethyl)amino)benzenebutanoic Acid .
Amboclorin .
CB-1348 .
Chloraminophene .
Chlorbutin .
Leukeran .
Lympholysin .
N,N-Di-(2-chloroethyl)-p-aminophenylbutyric Acid .
NSC-3088 .
CB 1348 .
CB1348 .
NSC 3088 .
NSC3088 .
A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed) .
0.53
353401
 
Ethylene Chlorohydrin .
Ethylenechlorhydrin .
2 Chlorethanol .
2 Chloroethyl Alcohol .
Alcohol, 2-Chloroethyl .
Chlorohydrin, Ethylene .
2-Chlorethanol .
2-Chloroethyl Alcohol .
Used as a solvent, in the manufacture of insecticides, and for treating sweet potatoes before planting. May cause nausea, vomiting, pains in head and chest, stupefaction. Irritates mucous membranes and causes kidney and liver degeneration. .
0.53
1290
 
Methylenebis(chloroaniline) .
3,3'-Dichloro-4,4'-Diaminodiphenylmethane .
4,4'-Methylenebis(2-chloroaniline) .
MBOCA .
Methylene Bis(chloroaniline) .
Aromatic diamine used in the plastics industry as curing agent for epoxy resins and urethane rubbers. It causes bladder, liver, lung, and other neoplasms. .
0.52
2111