serw-MX  [xml]  
 


    
 DeCS Categories

A05 Urogenital System .
A05.810 Urinary Tract .
A05.810.453 Kidney .
A05.810.453.736 Nephrons .
B01 Eukaryota .
B01.650 Plants .
B01.650.940 Viridiplantae .
B01.650.940.800 Streptophyta .
B01.650.940.800.575 Embryophyta .
B01.650.940.800.575.912 Tracheophyta .
B01.650.940.800.575.912.250 Magnoliopsida .
B01.650.940.800.575.912.250.096 Aristolochiaceae .
B01.650.940.800.575.912.250.096.211 Aristolochia .
D01 Inorganic Chemicals .
D01.045 Alkalies .
D01.045.250 Hydroxides .
D01.045.250.050 Aluminum Hydroxide .
D01.056 Aluminum Compounds .
D01.056.037 Aluminum Hydroxide .
D01.248 Electrolytes .
D01.248.497 Ions 5743 .
D01.248.497.158 Anions .
D01.248.497.158.459 Hydroxides .
D01.248.497.158.459.075 Aluminum Hydroxide .
D02 Organic Chemicals .
D02.455 Hydrocarbons .
D02.455.426 Hydrocarbons, Cyclic .
D02.455.426.559 Hydrocarbons, Aromatic .
D02.455.426.559.847 Polycyclic Aromatic Hydrocarbons .
D02.455.426.559.847.723 Phenanthrenes .
D02.455.426.559.847.723.089 Aristolochic Acids .
D02.640 Nitro Compounds .
D02.640.139 Aristolochic Acids .
D04 Polycyclic Compounds .
D04.615 Polycyclic Aromatic Hydrocarbons .
D04.615.723 Phenanthrenes .
D04.615.723.089 Aristolochic Acids .
D27 Chemical Actions and Uses .
D27.505 Pharmacologic Actions .
D27.505.519 Molecular Mechanisms of Pharmacological Action .
D27.505.519.124 Alkylating Agents .
D27.888 Toxic Actions .
D27.888.569 Noxae .
D27.888.569.035 Alkylating Agents .
G02 Chemical Phenomena .
G02.111 Biochemical Phenomena .
G02.111.035 Alkylation .
G02.607 Organic Chemistry Phenomena .
G02.607.094 Alkylation .
G03 Metabolism .
G03.059 Alkylation .
H02 Health Occupations .
H02.403 Medicine .
H02.403.429 Internal Medicine .
H02.403.429.580 Nephrology .
 
 Terms
 Synonyms & Historicals
Documents
LILACS e MDL
 
Aristolochic Acids .
Nitro-phenanthrenes occurring in ARISTOLOCHIACEAE and other plants. They derive from stephanine (APORPHINES) by oxidative ring cleavage. The nitro group is a reactive alkylator (ALKYLATING AGENTS) that binds to biological macromolecules. Ingestion by humans is associated with nephropathy (NEPHRITIS). There is no relationship to the similar named aristolochene (SESQUITERPENES). .
1.00
0804
 
Alkylating Agents .
Alkylators .
Agents, Alkylating .
Highly reactive chemicals that introduce alkyl radicals into biologically active molecules and thereby prevent their proper functioning. Many are used as antineoplastic agents, but most are very toxic, with carcinogenic, mutagenic, teratogenic, and immunosuppressant actions. They have also been used as components in poison gases. .
0.35
406645
 
Aristolochia .
Aristolochias .
Birthworts .
Dutchman Pipe .
Dutchman's Pipes .
Dutchmans Pipe .
Pipe, Dutchman's .
Pipes, Dutchman's .
Birthwort .
Dutchman's Pipe .
A plant genus of the family ARISTOLOCHIACEAE. Species of this genus have been used in traditional medicine but they contain aristolochic acid which is associated with nephropathy. These are sometimes called 'snakeroot' but that name is also used with a number of other plants such as POLYGALA; SANICULA; ASARUM; ARISTOLOCHIA; AGERATINA; and others. .
0.32
9265
 
Alkylation .
Alkylations .
The covalent bonding of an alkyl group to an organic compound. It can occur by a simple addition reaction or by substitution of another functional group. .
0.32
410043
 
Nephrons .
Nephron .
The functional units of the kidney, consisting of the glomerulus and the attached tubule. .
0.31
354593
 
Aluminum Hydroxide .
Aldrox .
Algeldrate .
Alhydrogel .
Alugel .
Amphojel .
Basalgel .
Brasivil .
Dialume .
Nephrox .
Pepsamer .
Rocgel .
Alumina, Hydrated .
Hydroxide, Aluminum .
Hydrated Alumina .
Aluminum Hydroxide Gel .
A compound with many biomedical applications: as a gastric antacid, an antiperspirant, in dentifrices, as an emulsifier, as an adjuvant in bacterins and vaccines, in water purification, etc. .
0.31
433321
 
Nephrology .
A subspecialty of internal medicine concerned with the anatomy, physiology, and pathology of the kidney. .
0.31
3244901