serw-MX  [xml]  
 


    
 DeCS Categories

C04 Neoplasms .
C04.697 Neoplastic Processes .
C04.697.098 Carcinogenesis .
C23 Pathological Conditions, Signs and Symptoms .
C23.550 Pathologic Processes .
C23.550.727 Neoplastic Processes .
C23.550.727.098 Carcinogenesis .
D27 Chemical Actions and Uses .
D27.888 Toxic Actions .
D27.888.569 Noxae .
D27.888.569.100 Carcinogens .
G05 Genetic Phenomena .
G05.360 Genetic Structures .
G05.360.340 Genome .
G05.360.340.024 Genome Components .
G05.360.340.024.340 Genes .
G05.360.340.024.340.375 Genes, Neoplasm .
G05.360.340.024.340.375.249 Genes, Tumor Suppressor .
G05.360.340.024.340.375.500 Oncogenes .
G05.360.340.024.340.375.500.791 Proto-Oncogenes .
G05.360.340.024.340.375.500.791.552 Genes, rel .
G05.360.340.024.340.415 Genes, Recessive .
G05.360.340.024.340.415.400 Genes, Tumor Suppressor .
SP4 Environmental Health .
SP4.001 Health .
SP4.001.012 Environmental Illness .
SP4.001.012.098 Neoplasms .
SP4.001.012.098.054 Carcinogens .
 
 Terms
 Synonyms & Historicals
Documents
LILACS e MDL
 
Oncogenes .
Oncogene .
Transforming Gene .
Gene, Transforming .
Genes, Transforming .
Transforming Genes .
Genes whose gain-of-function alterations lead to NEOPLASTIC CELL TRANSFORMATION. They include, for example, genes for activators or stimulators of CELL PROLIFERATION such as growth factors, growth factor receptors, protein kinases, signal transducers, nuclear phosphoproteins, and transcription factors. A prefix of "v-" before oncogene symbols indicates oncogenes captured and transmitted by RETROVIRUSES; the prefix "c-" before the gene symbol of an oncogene indicates it is the cellular homolog (PROTO-ONCOGENES) of a v-oncogene. .
1.00
23014393
 
Carcinogens .
Initiators, Tumor .
Promoters, Tumor .
Oncogens .
Tumor Initiators .
Tumor Promoters .
Substances that increase the risk of NEOPLASMS in humans or animals. Both genotoxic chemicals, which affect DNA directly, and nongenotoxic chemicals, which induce neoplasms by other mechanism, are included. .
0.91
24739950
 
Carcinogenesis .
Oncogenesis .
Carcinogeneses .
Oncogeneses .
Tumorigeneses .
Tumorigenesis .
The origin, production or development of cancer through genotypic and phenotypic changes which upset the normal balance between cell proliferation and cell death. Carcinogenesis generally requires a constellation of steps, which may occur quickly or over a period of many years. .
0.89
706412
 
Proto-Oncogenes .
Proto-Oncogene .
Proto Oncogene .
Proto Oncogenes .
Normal cellular genes homologous to viral oncogenes. The products of proto-oncogenes are important regulators of biological processes and appear to be involved in the events that serve to maintain the ordered procession through the cell cycle. Proto-oncogenes have names of the form c-onc. .
0.81
447439
 
Genes, Tumor Suppressor .
Anti-Oncogenes .
Genes, Onco-Suppressor .
Oncogenes, Recessive .
Tumor Suppressing Genes .
Anti Oncogenes .
Anti-Oncogene .
Antioncogene .
Cancer Suppressor Gene .
Emerogene .
Gene, Cancer Suppressor .
Gene, Growth Suppressor .
Gene, Metastasis Suppressor .
Gene, Onco-Suppressor .
Gene, Tumor Suppressing .
Gene, Tumor Suppressor .
Genes, Onco Suppressor .
Genes, Tumor Suppressing .
Growth Suppressor Gene .
Metastasis Suppressor Gene .
Onco-Suppressor Gene .
Onco-Suppressor Genes .
Oncogene, Recessive .
Recessive Oncogene .
Recessive Oncogenes .
Suppressor Gene, Cancer .
Suppressor Gene, Growth .
Suppressor Gene, Metastasis .
Suppressor Genes, Cancer .
Suppressor Genes, Growth .
Suppressor Genes, Metastasis .
Tumor Suppressing Gene .
Tumor Suppressor Gene .
Antioncogenes .
Cancer Suppressor Genes .
Emerogenes .
Genes, Cancer Suppressor .
Genes, Growth Suppressor .
Genes, Metastasis Suppressor .
Growth Suppressor Genes .
Metastasis Suppressor Genes .
Tumor Suppressor Genes .
GENES ,GROWTH SUPPRESSOR .
GENES, SUPPRESSOR, TUMOR .
Genes that inhibit expression of the tumorigenic phenotype. They are normally involved in holding cellular growth in check. When tumor suppressor genes are inactivated or lost, a barrier to normal proliferation is removed and unregulated growth is possible. .
0.81
11114943
 
Genes, rel .
c-rel Proto-Oncogenes .
rel Oncogene .
v-rel Oncogenes .
Gene, c-rel .
Gene, rel .
Gene, v-rel .
Genes, c-rel .
Genes, v-rel .
Oncogene, rel .
Oncogene, v-rel .
Oncogenes, rel .
Oncogenes, v-rel .
Proto-Oncogene, c-rel .
Proto-Oncogenes, c-rel .
c rel Genes .
c rel Proto Oncogenes .
c-rel Gene .
c-rel Proto-Oncogene .
rel Gene .
rel Oncogenes .
v rel Genes .
v rel Oncogenes .
v-rel Gene .
v-rel Oncogene .
c-rel Genes .
rel Genes .
v-rel Genes .
Family of retrovirus-associated DNA sequences (v-rel) originally isolated from an avian reticuloendotheliosis virus strain. The proto-oncogene rel (c-rel) codes for a subcellular (nuclear and cytoplasmic) transcription factor that has a role in lymphocyte differentiation. Translocation or overexpression of c-rel or competition from v-rel causes oncogenesis. The human rel gene is located at 2p12-13 on the short arm of chromosome 2. .
0.80
087