serw-MX  [xml]  
 


    
 DeCS Categories

D02 Organic Chemicals .
D02.455 Hydrocarbons .
D02.455.426 Hydrocarbons, Cyclic .
D02.455.426.559 Hydrocarbons, Aromatic .
D02.455.426.559.389 Benzene Derivatives .
D02.455.426.559.389.150 Benzylidene Compounds .
D02.455.426.559.389.150.700 Stilbenes .
D02.455.426.559.389.150.700.900 Tamoxifen .
D02.455.426.559.389.150.700.900.775 Raloxifene Hydrochloride .
D02.455.426.559.389.150.700.900.900 Toremifene .
D04 Polycyclic Compounds .
D04.210 Fused-Ring Compounds .
D04.210.500 Steroids .
D04.210.500.365 Estranes .
D04.210.500.365.415 Estrenes .
D04.210.500.365.415.414 Estrone .
D04.210.500.578 Ketosteroids .
D04.210.500.578.502 17-Ketosteroids .
D04.210.500.578.502.497 Estrone .
D06 Hormones, Hormone Substitutes, and Hormone Antagonists .
D06.347 Hormone Antagonists .
D06.347.295 Estrogen Antagonists .
D06.347.360 Estrogen Receptor Modulators .
D06.347.360.827 Selective Estrogen Receptor Modulators .
D06.472 Hormones .
D06.472.040 Adrenal Cortex Hormones .
D06.472.040.502 17-Ketosteroids .
D06.472.040.502.497 Estrone .
D06.472.334 Gonadal Hormones .
D06.472.334.851 Gonadal Steroid Hormones .
D06.472.334.851.437 Estradiol Congeners .
D06.472.334.851.437.996 Estrone .
D27 Chemical Actions and Uses .
D27.505 Pharmacologic Actions .
D27.505.696 Physiological Effects of Drugs .
D27.505.696.399 Hormones, Hormone Substitutes, and Hormone Antagonists .
D27.505.696.399.450 Hormone Antagonists .
D27.505.696.399.450.327 Estrogen Antagonists .
D27.505.696.399.450.360 Estrogen Receptor Modulators .
D27.505.696.399.450.360.827 Selective Estrogen Receptor Modulators .
D27.505.696.399.472 Hormones .
D27.505.696.399.472.277 Estrogens .
 
 Terms
 Synonyms & Historicals
Documents
LILACS e MDL
 
Tamoxifen .
ICI-46,474 .
ICI-46474 .
ICI-47699 .
Nolvadex .
Novaldex .
Soltamox .
Tamoxifen Citrate .
Tomaxithen .
Zitazonium .
Citrate, Tamoxifen .
ICI 46,474 .
ICI 46474 .
ICI 47699 .
ICI46,474 .
ICI46474 .
ICI47699 .
One of the SELECTIVE ESTROGEN RECEPTOR MODULATORS with tissue-specific activities. Tamoxifen acts as an anti-estrogen (inhibiting agent) in the mammary tissue, but as an estrogen (stimulating agent) in cholesterol metabolism, bone density, and cell proliferation in the ENDOMETRIUM. .
1.00
24717761
 
Toremifene .
FC-1157a .
Fareston .
Toremifene Citrate .
Toremifene Citrate (1:1) .
Toremifene, (E)-Isomer .
Citrate, Toremifene .
FC 1157a .
FC1157a .
A first generation selective estrogen receptor modulator (SERM). Like TAMOXIFEN, it is an estrogen agonist for bone tissue and cholesterol metabolism but is antagonistic on mammary and uterine tissue. .
0.52
4537
 
Estrogens .
Estrogen .
Estrogen Effect .
Estrogen Effects .
Estrogen Receptor Agonists .
Estrogenic Agents .
Estrogenic Compounds .
Estrogenic Effect .
Estrogenic Effects .
Agents, Estrogenic .
Agonists, Estrogen Receptor .
Compounds, Estrogenic .
Effects, Estrogen .
Effects, Estrogenic .
Receptor Agonists, Estrogen .
Compounds that interact with ESTROGEN RECEPTORS in target tissues to bring about the effects similar to those of ESTRADIOL. Estrogens stimulate the female reproductive organs, and the development of secondary female SEX CHARACTERISTICS. Estrogenic chemicals include natural, synthetic, steroidal, or non-steroidal compounds. .
0.45
74847035
 
Raloxifene Hydrochloride .
Evista .
Keoxifene .
Keoxifene Hydrochloride .
LY 139481 .
LY 156758 .
LY-139481 .
LY-156758 .
Raloxifene HCl .
LY139481 .
LY156758 .
Raloxifene .
LY 156758 .
A second generation selective estrogen receptor modulator (SERM) used to prevent osteoporosis in postmenopausal women. It has estrogen agonist effects on bone and cholesterol metabolism but behaves as a complete estrogen antagonist on mammary gland and uterine tissue. .
0.43
652480
 
Selective Estrogen Receptor Modulators .
Estrogen Receptor Modulator, Selective .
SERM 22213 .
Selective Estrogen Receptor Modulator .
Estrogen Receptor Modulators, Selective .
SERMs .
A structurally diverse group of compounds distinguished from ESTROGENS by their ability to bind and activate ESTROGEN RECEPTORS but act as either an agonist or antagonist depending on the tissue type and hormonal milieu. They are classified as either first generation because they demonstrate estrogen agonist properties in the ENDOMETRIUM or second generation based on their patterns of tissue specificity. (Horm Res 1997;48:155-63) .
0.39
473721
 
Estrogen Antagonists .
Estradiol Antagonists .
Antagonists, Estradiol .
Antagonists, Estrogen .
Compounds which inhibit or antagonize the action or biosynthesis of estrogenic compounds. .
0.37
597739
 
Estrone .
Estrone, (+-)-Isomer .
Estrone, (8 alpha)-Isomer .
Estrone, (9 beta)-Isomer .
Estrovarin .
Folliculin .
Kestrone .
Unigen .
Wehgen .
An aromatized C18 steroid with a 3-hydroxyl group and a 17-ketone, a major mammalian estrogen. It is converted from ANDROSTENEDIONE directly, or from TESTOSTERONE via ESTRADIOL. In humans, it is produced primarily by the cyclic ovaries, PLACENTA, and the ADIPOSE TISSUE of men and postmenopausal women. .
0.36
238115