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 DeCS Categories

D08 Enzymes and Coenzymes .
D08.244 Cytochromes .
D08.244.453 Cytochrome P-450 Enzyme System .
D08.244.453.498 Cytochrome P450 Family 26 .
D08.244.453.498.500 Retinoic Acid 4-Hydroxylase .
D08.811 Enzymes .
D08.811.277 Hydrolases .
D08.811.277.040 Acid Anhydride Hydrolases .
D08.811.277.040.025 Adenosine Triphosphatases .
D08.811.277.040.025.314 P-type ATPases .
D08.811.277.040.025.314.500 Copper-transporting ATPases .
D08.811.277.656 Peptide Hydrolases .
D08.811.682 Oxidoreductases .
D08.811.682.690 Oxygenases .
D08.811.682.690.708 Mixed Function Oxygenases .
D08.811.682.690.708.170 Cytochrome P-450 Enzyme System .
D08.811.682.690.708.170.485 Cytochrome P450 Family 26 .
D08.811.682.690.708.170.485.500 Retinoic Acid 4-Hydroxylase .
D12 Amino Acids, Peptides, and Proteins .
D12.776 Proteins .
D12.776.157 Carrier Proteins .
D12.776.157.530 Membrane Transport Proteins .
D12.776.157.530.450 Ion Pumps .
D12.776.157.530.450.250 Cation Transport Proteins .
D12.776.157.530.450.250.656 Copper-transporting ATPases .
D12.776.157.530.813 P-type ATPases .
D12.776.157.530.813.500 Copper-transporting ATPases .
D12.776.422 Hemeproteins .
D12.776.422.220 Cytochromes .
D12.776.422.220.453 Cytochrome P-450 Enzyme System .
D12.776.422.220.453.498 Cytochrome P450 Family 26 .
D12.776.422.220.453.498.500 Retinoic Acid 4-Hydroxylase .
D12.776.543 Membrane Proteins .
D12.776.543.585 Membrane Transport Proteins .
D12.776.543.585.450 Ion Pumps .
D12.776.543.585.450.250 Cation Transport Proteins .
D12.776.543.585.450.250.656 Copper-transporting ATPases .
D12.776.543.585.813 P-type ATPases .
D12.776.543.585.813.500 Copper-transporting ATPases .
D27 Chemical Actions and Uses .
D27.505 Pharmacologic Actions .
D27.505.389 Metabolic Side Effects of Drugs and Substances .
D27.505.389.500 Cytochrome P-450 Enzyme Inhibitors .
D27.505.519 Molecular Mechanisms of Pharmacological Action .
D27.505.519.389 Enzyme Inhibitors .
D27.505.519.389.335 Cytochrome P-450 Enzyme Inhibitors .
 
 Terms
 Synonyms & Historicals
Documents
LILACS e MDL
 
Cytochrome P-450 Enzyme System .
CYP450 Family .
CYP450 Superfamily .
Cytochrome P-450 Enzymes .
Cytochrome P-450 Families .
Cytochrome P-450 Monooxygenase .
Cytochrome P-450 Oxygenase .
Cytochrome P-450 Superfamily .
Cytochrome P450 .
Cytochrome P450 Superfamily .
Cytochrome p450 Families .
P-450 Enzymes .
P450 Enzymes .
Cytochrome P 450 .
Cytochrome P 450 Dependent Monooxygenase .
Cytochrome P 450 Enzyme System .
Cytochrome P 450 Enzymes .
Cytochrome P 450 Families .
Cytochrome P 450 Monooxygenase .
Cytochrome P 450 Oxygenase .
Cytochrome P 450 Superfamily .
Enzymes, Cytochrome P-450 .
Enzymes, P-450 .
Enzymes, P450 .
Monooxygenase, Cytochrome P-450 .
Monooxygenase, Cytochrome P-450-Dependent .
P 450 Enzymes .
P-450 Enzymes, Cytochrome .
Superfamily, CYP450 .
Superfamily, Cytochrome P-450 .
Superfamily, Cytochrome P450 .
Cytochrome P-450 .
Cytochrome P-450-Dependent Monooxygenase .
A superfamily of hundreds of closely related HEMEPROTEINS found throughout the phylogenetic spectrum, from animals, plants, fungi, to bacteria. They include numerous complex monooxygenases (MIXED FUNCTION OXYGENASES). In animals, these P-450 enzymes serve two major functions: (1) biosynthesis of steroids, fatty acids, and bile acids; (2) metabolism of endogenous and a wide variety of exogenous substrates, such as toxins and drugs (BIOTRANSFORMATION). They are classified, according to their sequence similarities rather than functions, into CYP gene families (>40% homology) and subfamilies (>59% homology). For example, enzymes from the CYP1, CYP2, and CYP3 gene families are responsible for most drug metabolism. .
1.00
4439776
 
Cytochrome P-450 Enzyme Inhibitors .
Cytochrome P-450 Inhibitors .
Cytochrome P-450 Monooxygenase Inhibitors .
Cytochrome P-450 Oxygenase Inhibitors .
Cytochrome P-450-Dependent Monooxygenase Inhibitors .
P-450 Enzyme Inhibitors .
P450 Enzyme Inhibitors .
Cytochrome P 450 Dependent Monooxygenase Inhibitors .
Cytochrome P 450 Enzyme Inhibitors .
Cytochrome P 450 Inhibitors .
Cytochrome P 450 Monooxygenase Inhibitors .
Cytochrome P 450 Oxygenase Inhibitors .
Enzyme Inhibitors, P-450 .
Enzyme Inhibitors, P450 .
Inhibitors, Cytochrome P-450 .
Inhibitors, P-450 Enzyme .
Inhibitors, P450 Enzyme .
P 450 Enzyme Inhibitors .
P-450 Inhibitors, Cytochrome .
Drugs and compounds which inhibit or antagonize the biosynthesis or actions of CYTOCHROME P-450 ENZYMES. .
0.74
05278
 
/enzymology .
/enzyme activity .
/enzymes .
Used with organisms, except vertebrates, and with organs and tissues. It is also used with diseases for enzymes during the course of the disease, but excludes diagnostic enzyme tests, for which "diagnosis" is used. .
0.71
 
Enzymes .
Biocatalysts .
Biological molecules that possess catalytic activity. They may occur naturally or be synthetically created. Enzymes are usually proteins, however CATALYTIC RNA and CATALYTIC DNA molecules have also been identified. .
0.71
48425937
 
Copper-transporting ATPases .
ATP7A Protein .
ATP7B Cu-binding P type ATPase .
ATPase Copper Transporting alpha .
ATPase, Cu++ transporting, beta Polypeptide (Wilson Disease) .
Copper Pump 1 .
Copper-transporting ATPase .
Copper-transporting ATPase 1 .
Copper-transporting ATPase 2 .
Copper-transporting Adenosine Triphosphatases .
Cu(+)-transporting ATPases .
Cu-transporting ATPases .
Menkes Disease-associated Protein .
PINA Enzyme .
Pineal Night-specific ATPase .
Wilson Disease Cu-binding P Type ATPase .
Wilson Disease Protein .
ATP7B Cu binding P type ATPase .
ATPase 1, Copper-transporting .
ATPase, Copper-transporting .
ATPase, Pineal Night-specific .
ATPases, Copper-transporting .
ATPases, Cu-transporting .
Adenosine Triphosphatases, Copper-transporting .
Copper transporting ATPase .
Copper transporting ATPase 1 .
Copper transporting ATPase 2 .
Copper transporting ATPases .
Copper transporting Adenosine Triphosphatases .
Cu transporting ATPases .
Menkes Disease associated Protein .
Night-specific ATPase, Pineal .
Pineal Night specific ATPase .
Triphosphatases, Copper-transporting Adenosine .
Wilson Disease Cu binding P Type ATPase .
P-type ATPases which transport copper ions across membranes in prokaryotic and eukaryotic cells. They possess a conserved CYSTEINE-HISTIDINE-SERINE (CPx) amino acid motif within their transmembrane helices that functions in cation translocation and catalytic activation, and an N-terminal copper-binding CxxC motif that regulates enzyme activity. They play essential roles in intracellular copper homeostasis through regulating the uptake, efflux and storage of copper ions, and in cuproprotein biosynthesis. .
0.57
31178
 
Retinoic Acid 4-Hydroxylase .
CYP26A1 .
CYP26A1 Enzyme .
CYP26B1 .
CYP450 4-Hydroxylase .
Cytochrome P-450 26B1 .
Cytochrome P-450 CYP26B1 .
Cytochrome P450 26A1 Enzyme .
Cytochrome P450 4-Hydroxylase .
P450RAI .
RA-4-Hydroxylase .
Retinoic Acid-Metabolizing Enzyme, CYP26B1 .
CYP26B1, Cytochrome P-450 .
Cytochrome P 450 CYP26B1 .
Cytochrome P450 4 Hydroxylase .
Enzyme, CYP26A1 .
RA 4 Hydroxylase .
Retinoic Acid 4 Hydroxylase .
Retinoic Acid Metabolizing Enzyme, CYP26B1 .
A cytochrome P450 enzyme that resides in the ENDOPLASMIC RETICULUM. It catalyzes the conversion of trans-RETINOIC ACID to 4-hydroxyretinoic acid. .
0.56
0417
 
Peptide Hydrolases .
Esteroproteases .
Proteolytic Enzymes .
Peptidases .
Proteinases .
Proteases .
Hydrolases that specifically cleave the peptide bonds found in PROTEINS and PEPTIDES. Examples of sub-subclasses for this group include EXOPEPTIDASES and ENDOPEPTIDASES. .
0.54
21428511