serw-MX  [xml]  

 DeCS Categories

E01 Diagnosis .
E01.370 Diagnostic Techniques and Procedures .
E01.370.225 Clinical Laboratory Techniques .
E01.370.225.562 Genetic Testing .
E01.370.225.562.500 Pharmacogenomic Testing .
E05 Investigative Techniques .
E05.200 Clinical Laboratory Techniques .
E05.200.562 Genetic Testing .
E05.200.562.500 Pharmacogenomic Testing .
E05.393 Genetic Techniques .
E05.393.435 Genetic Testing .
E05.393.435.500 Pharmacogenomic Testing .
G03 Metabolism .
G03.787 Pharmacokinetics .
G05 Genetic Phenomena .
G05.365 Genetic Variation .
G05.365.795 Polymorphism, Genetic .
G05.365.795.446 Pharmacogenomic Variants .
G07 Physiological Phenomena .
G07.690 Pharmacological and Toxicological Phenomena .
G07.690.725 Pharmacokinetics .
H01 Natural Science Disciplines .
H01.158 Biological Science Disciplines .
H01.158.273 Biology .
H01.158.273.343 Genetics .
H01.158.273.343.750 Pharmacogenetics .
H01.158.703 Pharmacology .
H01.158.703.052 Pharmacogenetics .
H02 Health Occupations .
H02.628 Pharmacology .
H02.628.479 Pharmacogenetics .
N02 Health Care Facilities, Manpower, and Services .
N02.421 Health Services .
N02.421.308 Genetic Services .
N02.421.308.430 Genetic Testing .
N02.421.308.430.500 Pharmacogenomic Testing .
N02.421.726 Preventive Health Services .
N02.421.726.233 Diagnostic Services .
N02.421.726.233.221 Genetic Testing .
N02.421.726.233.221.500 Pharmacogenomic Testing .
 Synonyms & Historicals
Pharmacogenetics .
Pharmacogenomics .
A branch of genetics which deals with the genetic variability in individual responses to drugs and drug metabolism (BIOTRANSFORMATION). .
Pharmacogenomic Testing .
Pharmacogenetic Analysis .
Pharmacogenetic Screening .
Pharmacogenetic Study .
Pharmacogenetic Testing .
Pharmacogenomic Analysis .
Pharmacogenomic Screening .
Pharmacogenomic Study .
Pharmacogenetic Analyses .
Pharmacogenetic Screenings .
Pharmacogenetic Studies .
Pharmacogenetic Testings .
Pharmacogenomic Analyses .
Pharmacogenomic Screenings .
Pharmacogenomic Studies .
Pharmacogenomic Testings .
Studies, Pharmacogenetic .
The detection of genetic variability (e.g., PHARMACOGENOMIC VARIANTS) relevant to PHARMACOGENETICS and PRECISION MEDICINE. The purpose of such genetic testing is to help determine the most effective treatment options and their optimum dosages with least potential risks for DRUG-RELATED SIDE EFFECTS AND ADVERSE REACTIONS. .
Pharmacogenomic Variants .
Pharmacogenetic Variants .
Pharmacokinetic Genetic Variants .
Genetic Variant, Pharmacokinetic .
Genetic Variants, Pharmacokinetic .
Pharmacogenetic Variant .
Pharmacogenomic Variant .
Pharmacokinetic Genetic Variant .
Variant, Pharmacogenetic .
Variant, Pharmacogenomic .
Variants, Pharmacogenetic .
Variants, Pharmacogenomic .
Naturally occurring genetic variations associated with drug response (e.g., dosage, extent and rate of metabolic processes). While these variants are not markers for GENETIC PREDISPOSITION TO DISEASE they influence PHARMACOKINETICS and pharmacodynamics and often occur on genes encoding drug metabolism enzymes and transporters (e.g., ANGIOTENSIN CONVERTING ENZYME; CYTOCHROME P-450 CYP2D6). .
Pharmacokinetics .
Drug Kinetics .
Kinetics, Drug .
Dynamic and kinetic mechanisms of exogenous chemical and DRUG LIBERATION; ABSORPTION; BIOLOGICAL TRANSPORT; TISSUE DISTRIBUTION; BIOTRANSFORMATION; elimination; and DRUG TOXICITY as a function of dosage, and rate of METABOLISM. LADMER, ADME and ADMET are abbreviations for liberation, absorption, distribution, metabolism, elimination, and toxicology. .
/pharmacokinetics .
/tissue distribution .
/toxicokinetics .
/absorption .
/binding .
/biochemical transport .
/kinetics .
Used for the mechanism, dynamics and kinetics of exogenous chemical and drug absorption, biotransformation, distribution, release, transport, uptake and elimination as a function of dosage, extent and rate of metabolic processes. .