serw-MX  [xml]  
 


    
 DeCS Categories

D08 Enzymes and Coenzymes .
D08.811 Enzymes .
D08.811.277 Hydrolases .
D08.811.277.656 Peptide Hydrolases .
D08.811.277.656.300 Endopeptidases .
D08.811.277.656.300.760 Serine Endopeptidases .
D08.811.277.656.300.760.330 Fibrinolysin .
D08.811.277.656.959 Serine Proteases .
D08.811.277.656.959.350 Serine Endopeptidases .
D08.811.277.656.959.350.330 Fibrinolysin .
D12 Amino Acids, Peptides, and Proteins .
D12.644 Peptides .
D12.644.200 Fibrinopeptide A .
D12.776 Proteins .
D12.776.124 Blood Proteins .
D12.776.124.050 Acute-Phase Proteins .
D12.776.124.050.250 Fibrinogen .
D12.776.124.050.250.265 Fibrinogens, Abnormal .
D12.776.124.125 Blood Coagulation Factors .
D12.776.124.125.500 Fibrinogen .
D12.776.124.125.500.265 Fibrinogens, Abnormal .
D12.776.124.125.515 Fibrinopeptide A .
D12.776.124.270 Fibrin .
D12.776.124.270.300 Fibrin Fibrinogen Degradation Products .
D12.776.124.270.310 Fibrinopeptide A .
D12.776.811 Protein Precursors .
D12.776.811.300 Fibrinogen .
D12.776.811.300.290 Fibrin Fibrinogen Degradation Products .
D12.776.811.300.310 Fibrinopeptide A .
D23 Biological Factors .
D23.101 Biomarkers .
D23.101.340 Fibrinopeptide A .
D23.119 Blood Coagulation Factors .
D23.119.490 Fibrinogen .
D23.119.490.265 Fibrinogens, Abnormal .
D23.119.500 Fibrinopeptide A .
E01 Diagnosis .
E01.370 Diagnostic Techniques and Procedures .
E01.370.225 Clinical Laboratory Techniques .
E01.370.225.625 Hematologic Tests .
E01.370.225.625.115 Blood Coagulation Tests .
E01.370.225.625.115.870 Thrombin Time .
E05 Investigative Techniques .
E05.200 Clinical Laboratory Techniques .
E05.200.625 Hematologic Tests .
E05.200.625.115 Blood Coagulation Tests .
E05.200.625.115.870 Thrombin Time .
G09 Circulatory and Respiratory Physiological Phenomena .
G09.188 Blood Physiological Phenomena .
G09.188.840 Thrombin Time .
 
 Terms
 Synonyms & Historicals
Documents
LILACS e MDL
 
Fibrinogen .
Blood Coagulation Factor I .
gamma-Fibrinogen .
Factor I, Coagulation .
gamma Fibrinogen .
Factor I .
Coagulation Factor I .
Plasma glycoprotein clotted by thrombin, composed of a dimer of three non-identical pairs of polypeptide chains (alpha, beta, gamma) held together by disulfide bonds. Fibrinogen clotting is a sol-gel change involving complex molecular arrangements: whereas fibrinogen is cleaved by thrombin to form polypeptides A and B, the proteolytic action of other enzymes yields different fibrinogen degradation products. .
1.00
22429107
 
Thrombin Time .
Reptilase Times .
Thrombin Times .
Time, Reptilase .
Time, Thrombin .
Times, Reptilase .
Times, Thrombin .
Reptilase Time .
Clotting time of PLASMA mixed with a THROMBIN solution. It is a measure of the conversion of FIBRINOGEN to FIBRIN, which is prolonged by AFIBRINOGENEMIA, abnormal fibrinogen, or the presence of inhibitory substances, e.g., fibrin-fibrinogen degradation products, or HEPARIN. BATROXOBIN, a thrombin-like enzyme unaffected by the presence of heparin, may be used in place of thrombin. .
0.51
 
Fibrinopeptide A .
Fibrinopeptides A .
Two small peptide chains removed from the N-terminal segment of the alpha chains of fibrinogen by the action of thrombin during the blood coagulation process. Each peptide chain contains 18 amino acid residues. In vivo, fibrinopeptide A is used as a marker to determine the rate of conversion of fibrinogen to fibrin by thrombin. .
0.39
21316
 
Fibrinogens, Abnormal .
Abnormal Fibrinogens .
Fibrinogens which have a functional defect as the result of one or more amino acid substitutions in the amino acid sequence of normal fibrinogen. Abnormalities of the fibrinogen molecule may impair any of the major steps involved in the conversion of fibrinogen into stabilized fibrin, such as cleavage of the fibrinopeptides by thrombin, polymerization and cross-linking of fibrin. The resulting dysfibrinogenemias can be clinically silent or can be associated with bleeding, thrombosis or defective wound healing. .
0.36
5479
 
Fibrinolysin .
Fibrogammin .
Glu-Plasmin .
Protease F .
Thrombolysin .
Glu Plasmin .
Plasmin .
THROMBOLYSIN .
A product of the lysis of plasminogen (profibrinolysin) by PLASMINOGEN activators. It is composed of two polypeptide chains, light (B) and heavy (A), with a molecular weight of 75,000. It is the major proteolytic enzyme involved in blood clot retraction or the lysis of fibrin and quickly inactivated by antiplasmins. .
0.36
267334
 
Fibrin .
Antithrombin I .
A protein derived from FIBRINOGEN in the presence of THROMBIN, which forms part of the blood clot. .
0.35
9212888
 
Fibrin Fibrinogen Degradation Products .
Degradation Products, Fibrin .
Antithrombin VI .
Fibrin Fibrinogen Split Products .
Fibrin Degradation Products .
Soluble protein fragments formed by the proteolytic action of plasmin on fibrin or fibrinogen. FDP and their complexes profoundly impair the hemostatic process and are a major cause of hemorrhage in intravascular coagulation and fibrinolysis. .
0.35
307701