Oligonucleotides. Polymers made up of a few (2-20) nucleotides. In molecular genetics, they refer to a short sequence synthesized to match a region where a mutation is known to occur, and then used as a probe (OLIGONUCLEOTIDE PROBES). (Dorland, 28th ed) . 1.00
Oligonucleotide Probes. Probes, Oligodeoxyribonucleotide . Probes, Oligonucleotide . Probes, Oligoribonucleotide . Oligodeoxyribonucleotide Probes . Oligoribonucleotide Probes . Synthetic or natural oligonucleotides used in hybridization studies in order to identify and study specific nucleic acid fragments, e.g., DNA segments near or within a specific gene locus or gene. The probe hybridizes with a specific mRNA, if present. Conventional techniques used for testing for the hybridization product include dot blot assays, Southern blot assays, and DNA:RNA hybrid-specific antibody tests. Conventional labels for the probe include the radioisotope labels 32P and 125I and the chemical label biotin. . 0.34
Aminoimidazole Carboxamide. Ba 2756 . Carboxamide, Aminoimidazole . An imidazole derivative which is a metabolite of the antineoplastic agents BIC and DIC. By itself, or as the ribonucleotide, it is used as a condensation agent in the preparation of nucleosides and nucleotides. Compounded with orotic acid, it is used to treat liver diseases. . 0.34
Nucleotides. The monomeric units from which DNA or RNA polymers are constructed. They consist of a purine or pyrimidine base, a pentose sugar, and a phosphate group. (From King & Stansfield, A Dictionary of Genetics, 4th ed) . 0.33
Polymorphism, Genetic. Genetic Polymorphisms . Polymorphisms (Genetics) . Polymorphisms, Genetic . Polymorphism (Genetics) . Genetic Polymorphism . The regular and simultaneous occurrence in a single interbreeding population of two or more discontinuous genotypes. The concept includes differences in genotypes ranging in size from a single nucleotide site (POLYMORPHISM, SINGLE NUCLEOTIDE) to large nucleotide sequences visible at a chromosomal level. . 0.33
Dinucleoside Phosphates. Bis(5'-Nucleosidyl)Tetraphosphate . Dinucleoside Polyphosphates . Diphosphates, Dinucleoside . Monophosphates, Dinucleoside . Oligophosphates, Dinucleoside . Phosphates, Deoxydinucleoside . Phosphates, Dinucleoside . Polyphosphates, Dinucleoside . Tetraphosphates, Dinucleoside . Triphosphates, Dinucleoside . Bis(5'-Nucleosidyl)Oligophosphates . Bis(5'-Nucleosidyl)Phosphates . Deoxydinucleoside Phosphates . Dinucleoside Diphosphates . Dinucleoside Monophosphates . Dinucleoside Oligophosphates . Dinucleoside Tetraphosphates . Dinucleoside Triphosphates . A group of compounds which consist of a nucleotide molecule to which an additional nucleoside is attached through the phosphate molecule(s). The nucleotide can contain any number of phosphates. . 0.31
Chromosome Walking. Chromosome Walkings . Walking, Chromosome . Walkings, Chromosome . A technique with which an unknown region of a chromosome can be explored. It is generally used to isolate a locus of interest for which no probe is available but that is known to be linked to a gene which has been identified and cloned. A fragment containing a known gene is selected and used as a probe to identify other overlapping fragments which contain the same gene. The nucleotide sequences of these fragments can then be characterized. This process continues for the length of the chromosome. . 0.31
