Prenylamine. Corontin . Difril . Segontin . A drug formerly used in the treatment of angina pectoris but superseded by less hazardous drugs. Prenylamine depletes myocardial catecholamine stores and has some calcium channel blocking activity. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1406) . 1.00
Prenylation. Farnesylation . Geranylgeranylation . Isoprenylation . Attachment of isoprenoids (TERPENES) to other compounds, especially PROTEINS and FLAVONOIDS. . 0.75
Protein Prenylation. Protein Farnesylation . Protein Geranylgeranylation . Protein Polyisoprenylation . Farnesylation, Protein . Geranylgeranylation, Protein . Polyisoprenylation, Protein . Prenylation, Protein . Post-Translational Isoprenylation . Protein Isoprenylation . A post-translational modification of proteins by the attachment of an isoprenoid to the C-terminal cysteine residue. The isoprenoids used, farnesyl diphosphate or geranylgeranyl diphosphate, are derived from the same biochemical pathway that produces cholesterol. . 0.61
Acebutolol. Acebutolol Hydrochloride . Acetobutolol . Apo-Acebutolol . M & B 17803A . M&B-17803 A . Monitan . Neptal . Novo-Acebutolol . Prent . Rhotral . Sectral . Apo Acebutolol . ApoAcebutolol . M&B 17803 A . M&B17803 A . Novo Acebutolol . NovoAcebutolol . A cardioselective beta-1 adrenergic antagonist with little effect on the bronchial receptors. The drug has stabilizing and quinidine-like effects on cardiac rhythm, as well as weak inherent sympathomimetic action. . 0.59
Diphenylamine. In humans it may be irritating to mucous membranes. Methemoglobinemia has been produced experimentally. In veterinary use, it is one of active ingredients in topical agents for prevention and treatment of screwworm infestation. An indicator in tests for nitrate poisoning. . 0.52
Dimethylallyltranstransferase. Dolichyl Phosphate Synthetase . Geranylgeranyl Pyrophosphate Synthetase . Nerylpyrophosphate Synthetase . Synthetase, Geranylpyrophosphate . Synthetase, Nerylpyrophosphate . Geranylpyrophosphate Synthetase . Prenyltransferase . Dimethylallyltransferase . Farnesylpyrophosphate Synthetase . An enzyme that, in the pathway of cholesterol biosynthesis, catalyzes the condensation of isopentenyl pyrophosphate and dimethylallylpyrophosphate to yield pyrophosphate and geranylpyrophosphate. The enzyme then catalyzes the condensation of the latter compound with another molecule of isopentenyl pyrophosphate to yield pyrophosphate and farnesylpyrophosphate. EC 2.5.1.1. . 0.50
Phenethylamines. Phenylethylamines . A group of compounds that are derivatives of beta- aminoethylbenzene which is structurally and pharmacologically related to amphetamine. (From Merck Index, 11th ed) . 0.49
Aminobiphenyl Compounds. Compounds, Aminobiphenyl . Biphenylamines . Biphenyl compounds substituted in any position by one or more amino groups. Permitted are any substituents except fused rings. . 0.48
