serw-MX  [xml]  
 


    
 DeCS Categories

D01 Inorganic Chemicals .
D01.268 Elements .
D01.268.185 Chalcogens .
D01.268.185.550 Oxygen .
D01.362 Gases .
D01.362.670 Oxygen .
D08 Enzymes and Coenzymes .
D08.811 Enzymes .
D08.811.682 Oxidoreductases .
D08.811.682.690 Oxygenases .
D08.811.682.690.416 Dioxygenases .
D08.811.682.690.416.617 Prolyl Hydroxylases .
D08.811.682.690.416.617.750 Procollagen-Proline Dioxygenase .
D08.811.682.690.708 Mixed Function Oxygenases .
D08.811.682.690.708.660 Procollagen-Lysine, 2-Oxoglutarate 5-Dioxygenase .
D08.811.682.690.708.694 Prolyl Hydroxylases .
D08.811.682.690.708.694.750 Procollagen-Proline Dioxygenase .
D12 Amino Acids, Peptides, and Proteins .
D12.776 Proteins .
D12.776.811 Protein Precursors .
D12.776.811.690 Procollagen .
D12.776.860 Scleroproteins .
D12.776.860.300 Extracellular Matrix Proteins .
D12.776.860.300.250 Collagen .
D12.776.860.300.250.600 Procollagen .
D27 Chemical Actions and Uses .
D27.505 Pharmacologic Actions .
D27.505.519 Molecular Mechanisms of Pharmacological Action .
D27.505.519.389 Enzyme Inhibitors .
D27.505.519.389.740 Prolyl-Hydroxylase Inhibitors .
SP4 Environmental Health .
SP4.011 Science .
SP4.011.097 Chemistry .
SP4.011.097.063 Elements .
SP4.011.097.063.949 Oxygen .
 
 Terms
 Synonyms & Historicals
Documents
LILACS e MDL
 
Procollagen-Proline Dioxygenase .
Procollagen Prolyl 4-Hydroxylase .
4-Hydroxylase, Procollagen Prolyl .
Dioxygenase, Procollagen-Proline .
Hydroxylase, Protocollagen Prolyl .
Procollagen Proline Dioxygenase .
Procollagen Prolyl 4 Hydroxylase .
Prolyl 4-Hydroxylase, Procollagen .
Prolyl Hydroxylase, Protocollagen .
Protocollagen Prolyl Hydroxylase .
A mixed-function oxygenase that catalyzes the hydroxylation of a prolyl-glycyl containing peptide, usually in PROTOCOLLAGEN, to a hydroxyprolylglycyl-containing-peptide. The enzyme utilizes molecular OXYGEN with a concomitant oxidative decarboxylation of 2-oxoglutarate to SUCCINATE. The enzyme occurs as a tetramer of two alpha and two beta subunits. The beta subunit of procollagen-proline dioxygenase is identical to the enzyme PROTEIN DISULFIDE-ISOMERASES. .
1.00
 
Prolyl-Hydroxylase Inhibitors .
Proline Dioxygenase Inhibitors .
Proline Hydroxylase Inhibitors .
Dioxygenase Inhibitors, Proline .
Hydroxylase Inhibitors, Proline .
Inhibitors, Proline Dioxygenase .
Inhibitors, Proline Hydroxylase .
Inhibitors, Prolyl-Hydroxylase .
Prolyl Hydroxylase Inhibitors .
Compounds that inhibit the action of HYDROXYLASES that act on PROLINE to form HYDROXYPROLINE. .
0.67
 
Dioxygenases .
Non-heme iron-containing enzymes that incorporate two atoms of OXYGEN into the substrate. They are important in biosynthesis of FLAVONOIDS; GIBBERELLINS; and HYOSCYAMINE; and for degradation of AROMATIC HYDROCARBONS. .
0.65
 
Procollagen .
Procollagen Type M .
Protocollagen .
A biosynthetic precursor of collagen containing additional amino acid sequences at the amino-terminal and carboxyl-terminal ends of the polypeptide chains. .
0.65
 
Oxygen .
Oxygen-16 .
Oxygen 16 .
Dioxygen .
An element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration. .
0.61
 
Procollagen-Lysine, 2-Oxoglutarate 5-Dioxygenase .
Collagen Lysyl Hydroxylase .
Lysyl Hydroxylase .
2-Oxoglutarate 5-Dioxygenase Procollagen-Lysine .
2-Oxoglutarate Dioxygenase, Lysine .
5-Dioxygenase Procollagen-Lysine, 2-Oxoglutarate .
Dioxygenase, Lysine 2-Oxoglutarate .
Hydroxylase, Collagen Lysyl .
Hydroxylase, Lysine .
Hydroxylase, Lysyl .
Hydroxylase, Protocollagen Lysyl .
Lysine 2 Oxoglutarate Dioxygenase .
Procollagen Lysine, 2 Oxoglutarate 5 Dioxygenase .
Lysine 2-Oxoglutarate Dioxygenase .
Protocollagen Lysyl Hydroxylase .
Lysine Hydroxylase .
A mixed-function oxygenase that catalyzes the hydroxylation of peptidyllysine, usually in protocollagen, to peptidylhydroxylysine. The enzyme utilizes molecular oxygen with concomitant oxidative decarboxylation of the cosubstrate 2-oxoglutarate to succinate. EC 1.14.11.4. .
0.57