serw-MX  [xml]  
 


    
 DeCS Categories

D08 Enzymes and Coenzymes .
D08.811 Enzymes .
D08.811.682 Oxidoreductases .
D08.811.682.690 Oxygenases .
D08.811.682.690.416 Dioxygenases .
D08.811.682.690.416.617 Prolyl Hydroxylases .
D08.811.682.690.416.617.750 Procollagen-Proline Dioxygenase .
D08.811.682.690.708 Mixed Function Oxygenases .
D08.811.682.690.708.694 Prolyl Hydroxylases .
D08.811.682.690.708.694.750 Procollagen-Proline Dioxygenase .
D27 Chemical Actions and Uses .
D27.505 Pharmacologic Actions .
D27.505.519 Molecular Mechanisms of Pharmacological Action .
D27.505.519.389 Enzyme Inhibitors .
D27.505.519.389.480 Lipoxygenase Inhibitors .
D27.505.519.389.740 Prolyl-Hydroxylase Inhibitors .
D27.505.519.389.745 Protease Inhibitors .
 
 Terms
 Synonyms & Historicals
Documents
LILACS e MDL
 
Prolyl-Hydroxylase Inhibitors .
Proline Dioxygenase Inhibitors .
Proline Hydroxylase Inhibitors .
Dioxygenase Inhibitors, Proline .
Hydroxylase Inhibitors, Proline .
Inhibitors, Proline Dioxygenase .
Inhibitors, Proline Hydroxylase .
Inhibitors, Prolyl-Hydroxylase .
Prolyl Hydroxylase Inhibitors .
Compounds that inhibit the action of HYDROXYLASES that act on PROLINE to form HYDROXYPROLINE. .
1.00
 
Procollagen-Proline Dioxygenase .
Procollagen Prolyl 4-Hydroxylase .
4-Hydroxylase, Procollagen Prolyl .
Dioxygenase, Procollagen-Proline .
Hydroxylase, Protocollagen Prolyl .
Procollagen Proline Dioxygenase .
Procollagen Prolyl 4 Hydroxylase .
Prolyl 4-Hydroxylase, Procollagen .
Prolyl Hydroxylase, Protocollagen .
Protocollagen Prolyl Hydroxylase .
A mixed-function oxygenase that catalyzes the hydroxylation of a prolyl-glycyl containing peptide, usually in PROTOCOLLAGEN, to a hydroxyprolylglycyl-containing-peptide. The enzyme utilizes molecular OXYGEN with a concomitant oxidative decarboxylation of 2-oxoglutarate to SUCCINATE. The enzyme occurs as a tetramer of two alpha and two beta subunits. The beta subunit of procollagen-proline dioxygenase is identical to the enzyme PROTEIN DISULFIDE-ISOMERASES. .
0.67
 
Dioxygenases .
Non-heme iron-containing enzymes that incorporate two atoms of OXYGEN into the substrate. They are important in biosynthesis of FLAVONOIDS; GIBBERELLINS; and HYOSCYAMINE; and for degradation of AROMATIC HYDROCARBONS. .
0.63
 
Lipoxygenase Inhibitors .
12-Lipoxygenase Inhibitors .
15-Lipoxygenase Inhibitors .
5-Lipoxygenase Inhibitors .
Arachidonate 12-Lipoxygenase Inhibitors .
Arachidonate 15-Lipoxygenase Inhibitors .
Arachidonate 5-Lipoxygenase Inhibitors .
Inhibitors, Lipoxygenase .
12 Lipoxygenase Inhibitors .
12-Lipoxygenase Inhibitors, Arachidonate .
15 Lipoxygenase Inhibitors .
15-Lipoxygenase Inhibitors, Arachidonate .
5 Lipoxygenase Inhibitors .
5-Lipoxygenase Inhibitors, Arachidonate .
Arachidonate 12 Lipoxygenase Inhibitors .
Arachidonate 15 Lipoxygenase Inhibitors .
Arachidonate 5 Lipoxygenase Inhibitors .
Inhibitors, 12-Lipoxygenase .
Inhibitors, 15-Lipoxygenase .
Inhibitors, 5-Lipoxygenase .
Inhibitors, Arachidonate 12-Lipoxygenase .
Inhibitors, Arachidonate 15-Lipoxygenase .
Inhibitors, Arachidonate 5-Lipoxygenase .
Compounds that bind to and inhibit that enzymatic activity of LIPOXYGENASES. Included under this category are inhibitors that are specific for lipoxygenase subtypes and act to reduce the production of LEUKOTRIENES. .
0.61
 
Protease Inhibitors .
Antiproteases .
Protease Inhibitor .
Antagonists, Protease .
Hydrolase Inhibitors, Peptide .
Inhibitor, Protease .
Inhibitors, Endopeptidase .
Inhibitors, Peptidase .
Inhibitors, Peptide Hydrolase .
Inhibitors, Peptide Peptidohydrolase .
Inhibitors, Protease .
Peptidohydrolase Inhibitors, Peptide .
Endopeptidase Inhibitors .
Peptidase Inhibitors .
Peptide Hydrolase Inhibitors .
Peptide Peptidohydrolase Inhibitors .
Protease Antagonists .
Proteinase Inhibitors .
Compounds which inhibit or antagonize biosynthesis or actions of proteases (ENDOPEPTIDASES). .
0.60