serw-MX  [xml]  

 DeCS Categories

D08 Enzymes and Coenzymes .
D08.811 Enzymes .
D08.811.682 Oxidoreductases .
D08.811.682.690 Oxygenases .
D08.811.682.690.416 Dioxygenases .
D08.811.682.690.416.617 Prolyl Hydroxylases .
D08.811.682.690.416.617.750 Procollagen-Proline Dioxygenase .
D08.811.682.690.708 Mixed Function Oxygenases .
D08.811.682.690.708.694 Prolyl Hydroxylases .
D08.811.682.690.708.694.750 Procollagen-Proline Dioxygenase .
D27 Chemical Actions and Uses .
D27.505 Pharmacologic Actions .
D27.505.519 Molecular Mechanisms of Pharmacological Action .
D27.505.519.389 Enzyme Inhibitors .
D27.505.519.389.740 Prolyl-Hydroxylase Inhibitors .
 Synonyms & Historicals
Prolyl Hydroxylases .
Peptidyl Prolyl Hydroxylase .
Prolyl 4-Hydroxylase .
Prolyl Hydroxylase .
Hydroxylases, Prolyl .
Proline Hydroxylase .
Proline,2-Oxoglutarate 4-Dioxygenase .
Enzymes that specifically hydroxylate PROLINE residues on proteins. .
Mixed Function Oxygenases .
Mixed Function Oxidases .
Oxidases, Mixed Function .
Oxygenases, Mixed Function .
Hydroxylases .
Monooxygenases .
Widely distributed enzymes that carry out oxidation-reduction reactions in which one atom of the oxygen molecule is incorporated into the organic substrate; the other oxygen atom is reduced and combined with hydrogen ions to form water. They are also known as monooxygenases or hydroxylases. These reactions require two substrates as reductants for each of the two oxygen atoms. There are different classes of monooxygenases depending on the type of hydrogen-providing cosubstrate (COENZYMES) required in the mixed-function oxidation. .
Procollagen-Proline Dioxygenase .
Procollagen Prolyl 4-Hydroxylase .
4-Hydroxylase, Procollagen Prolyl .
Dioxygenase, Procollagen-Proline .
Hydroxylase, Protocollagen Prolyl .
Procollagen Proline Dioxygenase .
Procollagen Prolyl 4 Hydroxylase .
Prolyl 4-Hydroxylase, Procollagen .
Prolyl Hydroxylase, Protocollagen .
Protocollagen Prolyl Hydroxylase .
A mixed-function oxygenase that catalyzes the hydroxylation of a prolyl-glycyl containing peptide, usually in PROTOCOLLAGEN, to a hydroxyprolylglycyl-containing-peptide. The enzyme utilizes molecular OXYGEN with a concomitant oxidative decarboxylation of 2-oxoglutarate to SUCCINATE. The enzyme occurs as a tetramer of two alpha and two beta subunits. The beta subunit of procollagen-proline dioxygenase is identical to the enzyme PROTEIN DISULFIDE-ISOMERASES. .
Prolyl-Hydroxylase Inhibitors .
Proline Dioxygenase Inhibitors .
Proline Hydroxylase Inhibitors .
Dioxygenase Inhibitors, Proline .
Hydroxylase Inhibitors, Proline .
Inhibitors, Proline Dioxygenase .
Inhibitors, Proline Hydroxylase .
Inhibitors, Prolyl-Hydroxylase .
Prolyl Hydroxylase Inhibitors .
Compounds that inhibit the action of HYDROXYLASES that act on PROLINE to form HYDROXYPROLINE. .