Hypoxanthine Phosphoribosyltransferase. HGPRT . HPRTase . Hypoxanthine Guanine Phosphoribosyltransferase . Phosphoribosyltransferase, Guanine . Phosphoribosyltransferase, Hypoxanthine . Phosphoribosyltransferase, Hypoxanthine-Guanine . Pyrophosphorylase, IMP . Hypoxanthine-Guanine Phosphoribosyltransferase . IMP Pyrophosphorylase . Guanine Phosphoribosyltransferase . HPRT 5454 . An enzyme that catalyzes the conversion of 5-phosphoribosyl-1-pyrophosphate and hypoxanthine, guanine, or MERCAPTOPURINE to the corresponding 5'-mononucleotides and pyrophosphate. The enzyme is important in purine biosynthesis as well as central nervous system functions. Complete lack of enzyme activity is associated with the LESCH-NYHAN SYNDROME, while partial deficiency results in overproduction of uric acid. EC 2.4.2.8. . 1.00
Adenine Phosphoribosyltransferase. APRTase . Phosphoribosyltransferase, Adenine . Pyrophosphorylase, AMP . AMP Pyrophosphorylase . Transphosphoribosidase . An enzyme catalyzing the formation of AMP from adenine and phosphoribosylpyrophosphate. It can act as a salvage enzyme for recycling of adenine into nucleic acids. EC 2.4.2.7. . 0.76
Nicotinamide-Nucleotide Adenylyltransferase. ATP-NMN Adenylyltransferase . ATP NMN Adenylyltransferase . Adenylyltransferase, ATP-NMN . Adenylyltransferase, NMN . Adenylyltransferase, Nicotinamide Mononucleotide . Adenylyltransferase, Nicotinamide-Nucleotide . Mononucleotide Adenylyltransferase, Nicotinamide . Nicotinamide Nucleotide Adenylyltransferase . Pyrophosphorylase, NAD . NAD Pyrophosphorylase . Nicotinamide Mononucleotide Adenylyltransferase . NMN Adenylyltransferase . An enzyme that catalyzes reversibly the transfer of the adenylyl moiety of ATP to the phosphoryl group of NMN to form NAD+ and pyrophosphate. The enzyme is found predominantly in the nuclei and catalyzes the final reaction in the major pathway for the biosynthesis of NAD in mammals. . 0.75
Nicotinamide Phosphoribosyltransferase. NAMPT Protein . NAmPRTase . NMN Pyrophosphorylase . Colony-Enhancing Factor, Pre-B-Cell . Phosphoribosyltransferase, Nicotinamide . Pre B Cell Colony Enhancing Factor . Pre-B-Cell Colony-Enhancing Factor . Visfatin . An enzyme that catalyzes the formation of nicotinamide mononucleotide (NMN) from nicotinamide and 5-phosphoribosyl-1-pyrophosphate, the rate-limiting step in the biosynthesis of the NAD coenzyme. It is also known as a growth factor for early B-LYMPHOCYTES, or an ADIPOKINE with insulin-mimetic effects (visfatin). . 0.70
ATP Phosphoribosyltransferase. Phosphoribosyl ATP Pyrophosphorylase . Phosphoribosyltransferase, ATP . Pyrophosphorylase, Phosphoribosyl-ATP . Phosphoribosyl-ATP Pyrophosphorylase . An enzyme that catalyzes the first step of the pathway for histidine biosynthesis in Salmonella typhimurium. ATP reacts reversibly with 5-phosphoribosyl-1-pyrophosphate to yield N-1-(5'-phosphoribosyl)-ATP and pyrophosphate. EC 2.4.2.17. . 0.67