serw-MX  [xml]  
 


    
 DeCS Categories

D08 Enzymes and Coenzymes .
D08.811 Enzymes .
D08.811.074 DNA Repair Enzymes .
D08.811.074.766 MutL Proteins .
D08.811.074.766.500 MutL Protein Homolog 1 .
D08.811.277 Hydrolases .
D08.811.277.040 Acid Anhydride Hydrolases .
D08.811.277.040.025 Adenosine Triphosphatases .
D08.811.277.040.025.215 MutL Proteins .
D08.811.277.040.025.215.500 MutL Protein Homolog 1 .
D08.811.277.352 Esterases .
D08.811.277.352.355 Endonucleases .
D08.811.277.352.355.325 Endodeoxyribonucleases .
D08.811.277.352.355.325.350 Flap Endonucleases .
D12 Amino Acids, Peptides, and Proteins .
D12.776 Proteins .
D12.776.260 DNA-Binding Proteins .
D12.776.260.540 MutL Proteins .
D12.776.260.540.500 MutL Protein Homolog 1 .
D12.776.476 Intracellular Signaling Peptides and Proteins .
D12.776.476.024 Adaptor Proteins, Signal Transducing .
D12.776.476.024.381 Homer Scaffolding Proteins .
D12.776.543 Membrane Proteins .
D12.776.543.750 Receptors, Cell Surface .
D12.776.543.750.058 Patched Receptors .
D12.776.543.750.058.500 Patched-1 Receptor .
D12.776.624 Neoplasm Proteins .
D12.776.624.776 Tumor Suppressor Proteins .
D12.776.624.776.633 Patched Receptors .
D12.776.624.776.633.500 Patched-1 Receptor .
H02 Health Occupations .
H02.403 Medicine .
H02.403.740 Radiology .
H02.403.740.500 Nuclear Medicine .
 
 Terms
 Synonyms & Historicals
Documents
LILACS e MDL
 
Flap Endonucleases .
FEN-1 .
Fen1 Protein .
Flap Endonuclease-1 .
RAD2 Homolog-1 Nuclease .
RTH-1 Nuclease .
Endonuclease-1, Flap .
Endonucleases, Flap .
Flap Endonuclease 1 .
Nuclease, RTH-1 .
RAD2 Homolog 1 Nuclease .
RTH 1 Nuclease .
Endonucleases that remove 5' DNA sequences from a DNA structure called a DNA flap. The DNA flap structure occurs in double-stranded DNA containing a single-stranded break where the 5' portion of the downstream strand is too long and overlaps the 3' end of the upstream strand. Flap endonucleases cleave the downstream strand of the overlap flap structure precisely after the first base-paired nucleotide, creating a ligatable nick. .
1.00
1533
 
Nuclear Medicine .
Medicine, Atomic .
Medicine, Nuclear .
Radiology, Nuclear .
Atomic Medicine .
Nuclear Radiology .
A specialty field of radiology concerned with diagnostic, therapeutic, and investigative use of radioactive compounds. .
0.52
3645197
 
MutL Protein Homolog 1 .
COCA2 Protein .
Colon Cancer, Nonpolyposis Type 2 Protein .
MLH1 Protein .
MutL Homolog 1 .
Eukaryotic homolog of the bacterial MutL DNA MISMATCH REPAIR protein. It heterodimerizes with MISMATCH REPAIR ENDONUCLEASE PMS2 to form MutL alpha, which is recruited to DNA mismatch sites by the MUTS DNA MISMATCH-BINDING PROTEIN. Mutations in the human MLH1 gene are associated with COLORECTAL NEOPLASMS, HEREDITARY NONPOLYPOSIS. .
0.51
12876
 
Homer Scaffolding Proteins .
Homer 1 .
Homer 1 Proteins .
Homer 1C .
Homer 1C Proteins .
Homer 1a .
Homer 2 .
Homer 2 Proteins .
Homer 3 .
Homer 3 Proteins .
Homer Proteins .
Proteins, Homer .
Proteins, Homer 1 .
Proteins, Homer 1C .
Proteins, Homer 2 .
Proteins, Homer 3 .
Proteins, Homer Scaffolding .
Scaffolding Proteins, Homer .
Homer proteins belong to a family of adaptor and scaffold proteins which include Homer1, Homer2 and Homer3. Homer1 and Homer2 play a role in the regulation of calcium homeostasis, whereas Homer3 functions in stimulating changes in actin dynamics in neurons and T-cells. Homer proteins are best known as scaffold proteins at the post-synaptic density where they facilitate synaptic signaling. They function as a molecular switch in metabotropic glutamate receptor (MGluR) signaling, and are associated with human Fragile X syndrome. .
0.51
0483
 
Patched-1 Receptor .
PTCH1 Protein .
Patched Homolog-1 .
Patched Receptor-1 .
Patched-1 Protein .
Patched 1 Protein .
Patched 1 Receptor .
Patched Homolog 1 .
Patched Receptor 1 .
Receptor, Patched-1 .
Receptor-1, Patched .
A patched receptor for several HEDGEHOG PROTEINS that associates with the SMOOTHENED RECEPTOR to modulate hedgehog signaling. It is also a TUMOR SUPPRESSOR PROTEIN; mutations in the patched-1 gene are associated with BASAL CELL NEVUS SYNDROME; SQUAMOUS CELL CARCNIOMA of the ESOPHAGUS; trichoepitheliomas, and CARCINOMA, TRANSITIONAL CELL of the URINARY BLADDER. .
0.49
1882