Receptors, Drug. Drug Receptor . Receptor, Drug . Drug Receptors . Proteins that bind specific drugs with high affinity and trigger intracellular changes influencing the behavior of cells. Drug receptors are generally thought to be receptors for some endogenous substance not otherwise specified. . 0.56
HLA-DR5 Antigen. HLA-DR5 . Antigen, HLA-DR5 . HLA DR5 Antigen . A broad-specificity HLA-DR antigen that is associated with HLA-DRB1 CHAINS encoded by DRB1*11 and DRB1*12 alleles. . 0.54
Receptors, Thyroid Hormone. DIT Receptors . Diiodotyrosine Receptor . MIT Receptors . Monoiodotyrosine Receptors . Receptors, DIT . Receptors, MIT . Receptors, Monoiodotyrosine . Receptors, T3 . Receptors, T4 . T3 Receptor . T4 Receptor . Thyroid Hormone Receptor . Thyroxine Receptor . Diiodotyrosine Receptors . Thyroid Hormone Receptors . Thyroxine Receptors . Triiodothyronine Receptors . T3 Receptors . T4 Receptors . Receptors, Diiodotyrosine . Receptors, Thyroxine . Receptors, Triiodothyronine . TR BETA . TR ALPHA . Specific high affinity binding proteins for THYROID HORMONES in target cells. They are usually found in the nucleus and regulate DNA transcription. These receptors are activated by hormones that leads to transcription, cell differentiation, and growth suppression. Thyroid hormone receptors are encoded by two genes (GENES, ERBA): erbA-alpha and erbA-beta for alpha and beta thyroid hormone receptors, respectively. . 0.53
DCC Receptor. DCC Tumor Suppressor Protein . DCC-Netrin-1 Receptor . Deleted in Colorectal Carcinoma Protein . DCC Netrin 1 Receptor . Receptor, DCC . Receptor, DCC-Netrin-1 . A receptor for NETRIN-1 that contains four membrane distal (N-terminal) Ig-like C2 domains and six membrane proximal (C-terminal) fibronectin type III domains. It is expressed primarily in the nerve axons and differentiated intestinal cells and is required for AXON GUIDANCE, mediating axon attraction of neuronal GROWTH CONES; however, it may also trigger axon repulsion through association with the UNC5 netrin-1 receptor. DCC also induces APOPTOSIS when it is unbound from netrin-1. Deletions of the DCC gene are observed in tumor metastases and the protein is not expressed in undifferentiated COLORECTAL CARCINOMA cells. . 0.51
Receptors, Aryl Hydrocarbon. AH Receptor . Aryl Hydrocarbon Receptor . Dioxin Receptor . Polyaromatic Hydrocarbon Receptor . Polyaromatic Hydrocarbon Receptors . Receptors, 2,3,7,8-Tetrachlorodibenzo-p-dioxin . Receptors, Polyaromatic Hydrocarbon . Receptors, TCDD . TCDD Receptor . Receptor, AH . Receptor, Aryl Hydrocarbon . Receptor, Dioxin . Receptor, Polyaromatic Hydrocarbon . Receptor, TCDD . Aryl Hydrocarbon Receptors . AH Receptors . Dioxin Receptors . Receptors, AH . Receptors, Dioxin . TCDD Receptors . Cytoplasmic proteins that bind certain aryl hydrocarbons, translocate to the nucleus, and activate transcription of particular DNA segments. AH receptors are identified by their high-affinity binding to several carcinogenic or teratogenic environmental chemicals including polycyclic aromatic hydrocarbons found in cigarette smoke and smog, heterocyclic amines found in cooked foods, and halogenated hydrocarbons including dioxins and polychlorinated biphenyls. No endogenous ligand has been identified, but an unknown natural messenger with a role in cell differentiation and development is suspected. . 0.50