Receptors, Death Domain. Death Receptors . Receptors, DR Family . Receptors, Death Domain Family . DR Family Receptors . Death Domain Receptors . A family of cell surface receptors that signal via a conserved domain that extends into the cell CYTOPLASM. The conserved domain is referred to as a DEATH DOMAIN due to the fact that many of these receptors are involved in APOPTOSIS signaling pathways. Several DEATH DOMAIN RECEPTOR SIGNALING ADAPTOR PROTEINS can bind to the death domains of the activated receptors and through a complex series of interactions activate apoptotic mediators such as CASPASES. . 0.73
Receptors, Tumor Necrosis Factor, Member 25. Apo-3 Receptor . DR3 Receptor . Death Receptor 3 . Lymphocyte Associated Receptor of Death Protein . TNFRSF25 Receptor . TRAMP Receptor . WSL-1 Protein . Apo 3 Receptor . Receptor, Apo-3 . Receptor, DR3 . Receptor, TNFRSF25 . Receptor, TRAMP . WSL 1 Protein . Tumor Necrosis Factor Receptor Superfamily, Member 25 . A tumor necrosis factor receptor subtype with specificity for TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 15. It is found in tissues containing LYMPHOCYTES and may play a role in regulating lymphocyte homeostasis and APOPTOSIS. The activated receptor signals via a conserved death domain that associates with specific TNF RECEPTOR-ASSOCIATED FACTORS in the CYTOPLASM. . 0.63
