Tumor Necrosis Factor-alpha. Cachectin-Tumor Necrosis Factor . TNF Superfamily, Member 2 . TNFalpha . Tumor Necrosis Factor . Cachectin Tumor Necrosis Factor . Tumor Necrosis Factor alpha . Cachectin . TNF-alpha . Tumor Necrosis Factor Ligand Superfamily Member 2 . Tumor Necrosis Factor . Serum glycoprotein produced by activated MACROPHAGES and other mammalian MONONUCLEAR LEUKOCYTES. It has necrotizing activity against tumor cell lines and increases ability to reject tumor transplants. Also known as TNF-alpha, it is only 30% homologous to TNF-beta (LYMPHOTOXIN), but they share TNF RECEPTORS. . 0.76
Receptors, Mitogen. Mitogen Receptor . Receptor, Mitogen . Lectin Receptors . Mitogen Receptors . Receptors, Lectin . Glycoprotein molecules on the surface of B- and T-lymphocytes, that react with molecules of antilymphocyte sera, lectins, and other agents which induce blast transformation of lymphocytes. . 0.52
CD4 Antigens. CD4 Antigen . Receptors, Surface CD4 . Surface CD4 Receptor . Antigen, CD4 . Antigens, T-Cell T4 . CD4 Receptor, Surface . CD4 Receptors, Surface . Surface CD4 Receptors . T-Cell T4 Antigens . T4 Antigens, T Cell . Antigens, CD4 . CD4 Molecule . CD4 Receptors . Receptors, CD4 . T4 Antigens, T-Cell . 55-kDa antigens found on HELPER-INDUCER T-LYMPHOCYTES and on a variety of other immune cell types. They are members of the immunoglobulin supergene family and are implicated as associative recognition elements in MAJOR HISTOCOMPATIBILITY COMPLEX class II-restricted immune responses. On T-lymphocytes they define the helper/inducer subset. T4 antigens also serve as INTERLEUKIN-15 receptors and bind to the HIV receptors, binding directly to the HIV ENVELOPE PROTEIN GP120. . 0.51
Receptors, Cholinergic. ACh Receptors . Receptors, ACh . Sites, Cholinoceptive . Acetylcholine Receptors . Cholinergic Receptors . Cholinoceptive Sites . Cholinoceptors . Receptors, Acetylcholine . Cell surface proteins that bind acetylcholine with high affinity and trigger intracellular changes influencing the behavior of cells. Cholinergic receptors are divided into two major classes, muscarinic and nicotinic, based originally on their affinity for nicotine and muscarine. Each group is further subdivided based on pharmacology, location, mode of action, and/or molecular biology. . 0.51
Receptors, Cyclic AMP. Cyclic AMP Receptor . Receptors, cAMP . cAMP Receptor . Receptor, Cyclic AMP . Receptor, cAMP . Cyclic AMP Receptors . cAMP Receptors . Cell surface proteins that bind cyclic AMP with high affinity and trigger intracellular changes which influence the behavior of cells. The best characterized cyclic AMP receptors are those of the slime mold Dictyostelium discoideum. The transcription regulator CYCLIC AMP RECEPTOR PROTEIN of prokaryotes is not included nor are the eukaryotic cytoplasmic cyclic AMP receptor proteins which are the regulatory subunits of CYCLIC AMP-DEPENDENT PROTEIN KINASES. . 0.50
