Receptors, Cell Surface. Cell Surface Hormone Receptors . Endogenous Substances Receptors . Cell Surface Receptors . Receptors, Endogenous Substances . Hormone Receptors, Cell Surface . Cell surface proteins that bind signalling molecules external to the cell with high affinity and convert this extracellular event into one or more intracellular signals that alter the behavior of the target cell (From Alberts, Molecular Biology of the Cell, 2nd ed, pp693-5). Cell surface receptors, unlike enzymes, do not chemically alter their ligands. . 1.00
fas Receptor. CD95 Antigen . Fas Cell Surface Death Receptor . TNFRSF6 Receptor . fas Antigen . APO 1 Antigen . Receptor, TNFRSF6 . Receptor, fas . Antigens, CD95 . APO-1 Antigen . CD95 Antigens . fas Antigens . Tumor Necrosis Factor Receptor Superfamily, Member 6 . fas Receptors . Receptors, fas . A tumor necrosis factor receptor subtype found in a variety of tissues and on activated LYMPHOCYTES. It has specificity for FAS LIGAND and plays a role in regulation of peripheral immune responses and APOPTOSIS. Multiple isoforms of the protein exist due to multiple ALTERNATIVE SPLICING. The activated receptor signals via a conserved death domain that associates with specific TNF RECEPTOR-ASSOCIATED FACTORS in the CYTOPLASM. Mutations in the CD95 gene are associated with cases of autoimmune lymphoproliferative syndrome. . 0.71
CD4 Antigens. CD4 Antigen . Receptors, Surface CD4 . Surface CD4 Receptor . Antigen, CD4 . Antigens, T-Cell T4 . CD4 Receptor, Surface . CD4 Receptors, Surface . Surface CD4 Receptors . T-Cell T4 Antigens . T4 Antigens, T Cell . Antigens, CD4 . CD4 Molecule . CD4 Receptors . Receptors, CD4 . T4 Antigens, T-Cell . 55-kDa antigens found on HELPER-INDUCER T-LYMPHOCYTES and on a variety of other immune cell types. They are members of the immunoglobulin supergene family and are implicated as associative recognition elements in MAJOR HISTOCOMPATIBILITY COMPLEX class II-restricted immune responses. On T-lymphocytes they define the helper/inducer subset. T4 antigens also serve as INTERLEUKIN-15 receptors and bind to the HIV receptors, binding directly to the HIV ENVELOPE PROTEIN GP120. . 0.70