serw-MX  [xml]  

 DeCS Categories

D12 Amino Acids, Peptides, and Proteins .
D12.776 Proteins .
D12.776.543 Membrane Proteins .
D12.776.543.750 Receptors, Cell Surface .
D12.776.543.750.705 Receptors, Immunologic .
D12.776.543.750.705.940 Receptors, Scavenger .
D12.776.543.750.710 Receptors, Lipoprotein .
D12.776.543.750.710.450 Receptors, LDL .
D12.776.543.750.710.450.750 Receptors, Scavenger .
 Synonyms & Historicals
Receptors, LDL .
LDL Receptor .
LDL Receptors, Lipoprotein .
Low Density Lipoprotein Receptor .
Low Density Lipoprotein Receptors .
Receptors, Lipoprotein, LDL .
Receptor, LDL .
Receptors, Lipoprotein LDL .
LDL Receptors .
Lipoprotein LDL Receptors .
Receptors, Low Density Lipoprotein .
Receptors on the plasma membrane of nonhepatic cells that specifically bind LDL. The receptors are localized in specialized regions called coated pits. Hypercholesteremia is caused by an allelic genetic defect of three types: 1, receptors do not bind to LDL; 2, there is reduced binding of LDL; and 3, there is normal binding but no internalization of LDL. In consequence, entry of cholesterol esters into the cell is impaired and the intracellular feedback by cholesterol on 3-hydroxy-3-methylglutaryl CoA reductase is lacking. .
Receptors, Scavenger .
Acetyl-LDL Receptor .
Acetyl-LDL Receptors .
Acetylated LDL Receptor .
Macrophage Scavenger Receptor .
Receptor, Acetyl-LDL .
Receptor, Macrophage Scavenger .
Scavenger Receptor .
Acetyl LDL Receptor .
Acetyl LDL Receptors .
LDL Receptor, Acetylated .
Receptor, Acetyl LDL .
Receptor, Acetylated LDL .
Receptor, Scavenger .
Receptors, Acetyl-LDL .
Macrophage Scavenger Receptors .
Scavenger Receptors .
Scavenger Receptors, Macrophage .
A large group of structurally diverse cell surface receptors that mediate endocytic uptake of modified LIPOPROTEINS. Scavenger receptors are expressed by MYELOID CELLS and some ENDOTHELIAL CELLS, and were originally characterized based on their ability to bind acetylated LOW-DENSITY LIPOPROTEINS. They can also bind a variety of other polyanionic ligand. Certain scavenger receptors can internalize micro-organisms as well as apoptotic cells. .