serw-MX  [xml]  
 


    
 DeCS Categories

D12 Amino Acids, Peptides, and Proteins .
D12.776 Proteins .
D12.776.543 Membrane Proteins .
D12.776.543.750 Receptors, Cell Surface .
D12.776.543.750.710 Receptors, Lipoprotein .
D12.776.543.750.710.450 Receptors, LDL .
 
 Terms
 Synonyms & Historicals
Documents
LILACS e MDL
 
Receptors, Lipoprotein .
Lipoprotein Receptor .
Receptors, Lipoproteins .
Lipoproteins Receptors .
Receptor, Lipoprotein .
Lipoprotein Receptors .
Cell surface proteins that bind lipoproteins with high affinity. Lipoprotein receptors in the liver and peripheral tissues mediate the regulation of plasma and cellular cholesterol metabolism and concentration. The receptors generally recognize the apolipoproteins of the lipoprotein complex, and binding is often a trigger for endocytosis. .
1.00
61989
 
Receptors, LDL .
LDL Receptor .
LDL Receptors, Lipoprotein .
Low Density Lipoprotein Receptor .
Low Density Lipoprotein Receptors .
Receptors, Lipoprotein, LDL .
Receptor, LDL .
Receptors, Lipoprotein LDL .
LDL Receptors .
Lipoprotein LDL Receptors .
Receptors, Low Density Lipoprotein .
Receptors on the plasma membrane of nonhepatic cells that specifically bind LDL. The receptors are localized in specialized regions called coated pits. Hypercholesteremia is caused by an allelic genetic defect of three types: 1, receptors do not bind to LDL; 2, there is reduced binding of LDL; and 3, there is normal binding but no internalization of LDL. In consequence, entry of cholesterol esters into the cell is impaired and the intracellular feedback by cholesterol on 3-hydroxy-3-methylglutaryl CoA reductase is lacking. .
0.85
298898