serw-MX  [xml]  

 DeCS Categories

G02 Chemical Phenomena .
G02.111 Biochemical Phenomena .
G02.111.222 DNA Repair .
G05 Genetic Phenomena .
G05.219 DNA Repair .
 Synonyms & Historicals
DNA Repair .
Base Excision Repair .
Excision Repair .
Base Excision Repairs .
Excision Repair, Base .
Excision Repair, Nucleotide .
Excision Repairs .
Nucleotide Excision Repairs .
Repair, Base Excision .
Repair, Excision .
Repairs, Base Excision .
Nucleotide Excision Repair .
The reconstruction of a continuous two-stranded DNA molecule without mismatch from a molecule which contained damaged regions. The major repair mechanisms are excision repair, in which defective regions in one strand are excised and resynthesized using the complementary base pairing information in the intact strand; photoreactivation repair, in which the lethal and mutagenic effects of ultraviolet light are eliminated; and post-replication repair, in which the primary lesions are not repaired, but the gaps in one daughter duplex are filled in by incorporation of portions of the other (undamaged) daughter duplex. Excision repair and post-replication repair are sometimes referred to as "dark repair" because they do not require light. .