serw-MX  [xml]  
 


    
 DeCS Categories

D08 Enzymes and Coenzymes .
D08.811 Enzymes .
D08.811.277 Hydrolases .
D08.811.277.656 Peptide Hydrolases .
D08.811.277.656.300 Endopeptidases .
D08.811.277.656.300.760 Serine Endopeptidases .
D08.811.277.656.300.760.431 High-Temperature Requirement A Serine Peptidase 2 .
D08.811.277.656.959 Serine Proteases .
D08.811.277.656.959.350 Serine Endopeptidases .
D08.811.277.656.959.350.431 High-Temperature Requirement A Serine Peptidase 2 .
D12 Amino Acids, Peptides, and Proteins .
D12.644 Peptides .
D12.644.360 Intracellular Signaling Peptides and Proteins .
D12.644.360.075 Apoptosis Regulatory Proteins .
D12.644.360.075.429 High-Temperature Requirement A Serine Peptidase 2 .
D12.776 Proteins .
D12.776.476 Intracellular Signaling Peptides and Proteins .
D12.776.476.075 Apoptosis Regulatory Proteins .
D12.776.476.075.429 High-Temperature Requirement A Serine Peptidase 2 .
D12.776.575 Mitochondrial Proteins .
D12.776.575.656 High-Temperature Requirement A Serine Peptidase 2 .
D12.776.637 Parkinson Disease Associated Proteins .
D12.776.637.625 High-Temperature Requirement A Serine Peptidase 2 .
 
 Terms
 Synonyms & Historicals
Documents
LILACS e MDL
 
Serine Proteases .
Serine Protease .
Serine Protein Hydrolases .
Serine Proteinase .
Protease, Serine .
Proteases, Serine .
Protein Hydrolases, Serine .
Proteinase, Serine .
Proteinases, Serine .
Serine Proteinases .
Peptide hydrolases that contain at the active site a SERINE residue involved in catalysis. .
1.00
191389
 
High-Temperature Requirement A Serine Peptidase 2 .
HtrA Serine Peptidase 2 .
HtrA2 Protease .
Omi Serine Protease .
Serine Protease HTRA2 .
Serine Protease Omi .
HTRA2, Serine Protease .
High Temperature Requirement A Serine Peptidase 2 .
Omi, Serine Protease .
Protease HTRA2, Serine .
Protease Omi, Serine .
Protease, HtrA2 .
Protease, Omi Serine .
Serine Protease, Omi .
A serine peptidase that contains a C-terminal PDZ domain. It localizes to the mitochondrial membrane and intermembrane space, translocating to the cytoplasm following APOPTOSIS stimuli, such as UV irradiation; it promotes cell death by binding to and inhibiting INHIBITOR OF APOPTOSIS PROTEINS, resulting in an increase in activity of CASPASES. Mutations in the HTRA2 gene are associated with Type 13 PARKINSON DISEASE. .
0.77
0280