Tumor Necrosis Factor-alpha. Cachectin-Tumor Necrosis Factor . TNF Superfamily, Member 2 . TNFalpha . Tumor Necrosis Factor . Cachectin Tumor Necrosis Factor . Tumor Necrosis Factor alpha . Cachectin . TNF-alpha . Tumor Necrosis Factor Ligand Superfamily Member 2 . Tumor Necrosis Factor . Serum glycoprotein produced by activated MACROPHAGES and other mammalian MONONUCLEAR LEUKOCYTES. It has necrotizing activity against tumor cell lines and increases ability to reject tumor transplants. Also known as TNF-alpha, it is only 30% homologous to TNF-beta (LYMPHOTOXIN), but they share TNF RECEPTORS. . 1.00
Certolizumab Pegol. CDP 870 . CDP870 . Cimzia . A polyethylene-glycolated Fab' fragment of TUMOR NECROSIS FACTOR antibody that binds specifically to TNF-ALPHA and neutralises it in a dose-dependent manner. It also inhibits the production of lipopolysaccharide-induced TNF-ALPHA and IL-1 BETA and is used to treat RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS. . 0.39
Etanercept. Enbrel . Recombinant Human Dimeric TNF Receptor Type II-IgG Fusion Protein . TNF Receptor Type II-IgG Fusion Protein . TNFR-Fc Fusion Protein . TNR 001 . TNR-001 . TNT Receptor Fusion Protein . TNTR-Fc . 001, TNR . Fusion Protein, TNFR-Fc . Protein, TNFR-Fc Fusion . Recombinant Human Dimeric TNF Receptor Type II IgG Fusion Protein . TNF Receptor Type II IgG Fusion Protein . TNFR Fc Fusion Protein . TNR001 . A recombinant version of soluble human TNF receptor that binds specifically to TUMOR NECROSIS FACTOR and inhibits its binding with endogenous TNF receptors. It prevents the inflammatory effect of TNF and is used to treat RHEUMATOID ARTHRITIS; PSORIATIC ARTHRITIS and ANKYLOSING SPONDYLITIS. . 0.34
Lymphotoxin-alpha. Lymphotoxin . Lymphotoxin-alpha3 . Soluble Lymphotoxin-alpha . alpha-Lymphotoxin . Lymphotoxin alpha . Lymphotoxin alpha3 . Lymphotoxin-alpha, Soluble . Soluble Lymphotoxin alpha . Tumor Necrosis Factor beta . alpha Lymphotoxin . TNF Superfamily, Member 1 . TNF-beta . Tumor Necrosis Factor-beta . Tumor Necrosis Factor Ligand Superfamily Member 1 . A tumor necrosis factor family member that is released by activated LYMPHOCYTES. Soluble lymphotoxin is specific for TUMOR NECROSIS FACTOR RECEPTOR TYPE I; TUMOR NECROSIS FACTOR RECEPTOR TYPE II; and TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY, MEMBER 14. Lymphotoxin-alpha can form a membrane-bound heterodimer with LYMPHOTOXIN-BETA that has specificity for the LYMPHOTOXIN BETA RECEPTOR. . 0.33
CA-125 Antigen. CA 125 Antigen . Mucin-16 . Antigen CA 125 . Antigen, CA 125 . Antigen, CA-125 . Mucin 16 . Antigen CA-125 . A carbohydrate antigen that occurs in tumors of the ovary as well as in breast, kidney, and gastrointestinal tract tumors and normal tissue. While it is tumor-associated, it is not tumor-specific and may have a protective function against particles and infectious agents at mucosal surfaces. . 0.32
Receptors, Tumor Necrosis Factor, Type I. CD 120a Antigen . CD120a Antigen . TNFR p60 . TNFR-I . TNFR1 . TNFRSF1A (Tumor Necrosis Factor Receptor Superfamily, Member 1A) . TNFRSF1A Receptor . Tumor Necrosis Factor Receptor 1A . Tumor Necrosis Factor Receptor Type 1 . 120a Antigen, CD . Antigen, CD 120a . Antigen, CD120a . Receptor, TNFRSF1A . Antigens, CD120a . CD120a Antigens . Receptors, Tumor Necrosis Factor, Member 1A . Tumor Necrosis Factor Receptor Superfamily, Member 1A . Tumor Necrosis Factor Receptor Type I . A tumor necrosis factor receptor subtype that has specificity for TUMOR NECROSIS FACTOR ALPHA and LYMPHOTOXIN ALPHA. It is constitutively expressed in most tissues and is a key mediator of tumor necrosis factor signaling in the vast majority of cells. The activated receptor signals via a conserved death domain that associates with specific TNF RECEPTOR-ASSOCIATED FACTORS in the CYTOPLASM. . 0.32