Oxyphenonium. 2-((Cyclohexylhydroxyphenylacetyl)oxy)-N,N-diethyl-N-methylethanaminium . Atrenyl . Metacin . Methacin . Oxyphenon . Oxyphenonium Bromide, (+)-Isomer . Oxyphenonium Bromide, (+-)-Isomer . Oxyphenonium Bromide, (-)-Isomer . Oxyphenonium Iodide, (R)-Isomer . Oxyphenonium Iodide, (S)-Isomer . Oxyphenonium, (+-)-Isomer . Oxyphenonium, (R)-Isomer . Oxyphenonium, (S)-Isomer . Spastrex . Bromide, Oxyphenonium . Chloride, Oxyphenonium . Iodide, Oxyphenonium . Oxyphenonium Bromide . Oxyphenonium Chloride . Oxyphenonium Iodide . A quaternary ammonium anticholinergic agent with peripheral side effects similar to those of ATROPINE. It is used as an adjunct in the treatment of gastric and duodenal ulcer, and to relieve visceral spasms. The drug has also been used in the form of eye drops for mydriatic effect. . 1.00
Muscle Spasticity. Spastic . Clasp Knife Spasticity . Spasticity, Clasp-Knife . Spasticity, Muscle . Clasp-Knife Spasticity . SPASTICITY, MUSCLE . A form of muscle hypertonia associated with upper MOTOR NEURON DISEASE. Resistance to passive stretch of a spastic muscle results in minimal initial resistance (a "free interval") followed by an incremental increase in muscle tone. Tone increases in proportion to the velocity of stretch. Spasticity is usually accompanied by HYPERREFLEXIA and variable degrees of MUSCLE WEAKNESS. (From Adams et al., Principles of Neurology, 6th ed, p54) . 0.74
Spastin. Spastic Paraplegia 4 Protein . An AAA ATPase that binds and severs MICROTUBULES. It specifically recognizes and cuts polyglutamylated microtubules with short polyglutamate tails to promote reorganization of cellular microtubule arrays and the release of microtubules from the CENTROSOME following nucleation. It is critical for the biogenesis and maintenance of complex microtubule arrays in AXONS; SPINDLE APPARATUS; and CILIA. Mutations in the spastin gene (SPAST) are associated with type 4 of HEREDITARY SPASTIC PARAPLEGIA. . 0.74
Phloroglucinol. 1,3,5-Benzenetriol . Benzene-1,3,5-triol . Spasfon-Lyoc . Spassirex . A trinitrobenzene derivative with antispasmodic properties that is used primarily as a laboratory reagent. . 0.68
Dicyclomine. Bentyl . Bentylol . Di-Cyclonex . Di-Spaz . Dibent . Diclomin . Dicyclomine Hydrochloride . Lomine . Merbentyl . OR-Tyl . Spascol . Di Cyclonex . Di Spaz . Hydrochloride, Dicyclomine . OR Tyl . Dicycloverin . A muscarinic antagonist used as an antispasmodic and in urinary incontinence. It has little effect on glandular secretion or the cardiovascular system. It does have some local anesthetic properties and is used in gastrointestinal, biliary, and urinary tract spasms. . 0.61
Flavoxate. Bladuril . Flavoxate Hydrochloride . Spasuret . Urispas . Uronid . Hydrochloride, Flavoxate . A drug that has been used in various urinary syndromes and as an antispasmodic. Its therapeutic usefulness and its mechanism of action are not clear. It may have local anesthetic activity and direct relaxing effects on smooth muscle as well as some activity as a muscarinic antagonist. . 0.59
Spain. Balearic Islands . Canary Islands . Country located between France on the northeast and Portugal on the west and bordered by the Atlantic Ocean and the Mediterranean Sea. The capital is Madrid. . 0.58
Dexetimide. Dexbenzetimid . R-16470 . Spasmentral . Tremblex . dextro-Benzetimide . R 16470 . R16470 . dextro Benzetimide . Benzetimide . Dexbenzetimide . A muscarinic antagonist that has been used to treat neuroleptic-induced parkinsonism. Benzetimide is the (-)-enantimorph of dexetimide. . 0.54