serw-MX  [xml]  
 


    
 DeCS Categories

C10 Nervous System Diseases .
C10.228 Central Nervous System Diseases .
C10.228.140 Brain Diseases .
C10.228.140.380 Dementia .
C10.228.140.380.266 Frontotemporal Lobar Degeneration .
C10.228.140.380.266.299 Frontotemporal Dementia .
C10.574 Neurodegenerative Diseases .
C10.574.950 TDP-43 Proteinopathies .
C10.574.950.300 Frontotemporal Lobar Degeneration .
C10.574.950.300.299 Frontotemporal Dementia .
C18 Nutritional and Metabolic Diseases .
C18.452 Metabolic Diseases .
C18.452.845 Proteostasis Deficiencies .
C18.452.845.800 TDP-43 Proteinopathies .
C18.452.845.800.300 Frontotemporal Lobar Degeneration .
C18.452.845.800.300.299 Frontotemporal Dementia .
D12 Amino Acids, Peptides, and Proteins .
D12.776 Proteins .
D12.776.395 Glycoproteins .
D12.776.395.550 Membrane Glycoproteins .
D12.776.395.550.400 GAP-43 Protein .
D12.776.543 Membrane Proteins .
D12.776.543.550 Membrane Glycoproteins .
D12.776.543.550.400 GAP-43 Protein .
D12.776.631 Nerve Tissue Proteins .
D12.776.631.400 GAP-43 Protein .
F03 Mental Disorders .
F03.615 Neurocognitive Disorders .
F03.615.400 Dementia .
F03.615.400.380 Frontotemporal Lobar Degeneration .
F03.615.400.380.299 Frontotemporal Dementia .
 
 Terms
 Synonyms & Historicals
Documents
LILACS e MDL
 
TDP-43 Proteinopathies .
Proteinopathies, TDP-43 .
Proteinopathy, TDP-43 .
TDP 43 Proteinopathies .
TDP-43 Proteinopathy .
Diseases characterized by the presence of abnormally phosphorylated, ubiquitinated, and cleaved DNA-binding protein TDP-43 in affected brain and spinal cord. Inclusions of the pathologic protein in neurons and glia, without the presence of AMYLOID, is the major feature of these conditions, thus making these proteinopathies distinct from most other neurogenerative disorders in which protein misfolding leads to brain amyloidosis. Both frontotemporal lobar degeneration and AMYOTROPHIC LATERAL SCLEROSIS exhibit this common method of pathogenesis and thus they may represent two extremes of a continuous clinicopathological spectrum of one disease. .
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Frontotemporal Dementia .
DDPAC .
Dementia, Frontotemporal .
Dementia, Frontotemporal, with Parkinsonism .
Dementia, Hereditary Dysphasic Disinhibition .
Disinhibition-Dementia-Parkinsonism-Amyotrophy Complex .
Disinhibition-Dementia-Parkinsonism-Amytrophy Complex .
FTD-GRN .
FTD-PGRN .
FTDP-17 .
FTLD with TDP-43 Pathology .
FTLD-17 GRN .
FTLD-TDP .
Familial Pick's Disease .
Frontotemporal Dementia with Parkinsonism .
Frontotemporal Dementia with Parkinsonism-17 .
Frontotemporal Dementia, Ubiquitin-Positive .
Frontotemporal Lobar Degeneration With Ubiquitin-Positive Inclusions .
Frontotemporal Lobe Dementia .
Frontotemporal Lobe Dementia (FLDEM) .
GRN-Related Frontotemporal Dementia .
HDDD1 .
HDDD2 .
Hereditary Dysphasic Disinhibition Dementia .
Multiple System Tauopathy with Presenile Dementia .
Semantic Dementia .
Wilhelmsen-Lynch Disease .
Complex, Disinhibition-Dementia-Parkinsonism-Amyotrophy .
Complex, Disinhibition-Dementia-Parkinsonism-Amytrophy .
Complices, Disinhibition-Dementia-Parkinsonism-Amyotrophy .
Complices, Disinhibition-Dementia-Parkinsonism-Amytrophy .
Dementia, Frontotemporal Lobe .
Dementia, Frontotemporal Lobe (FLDEM) .
Dementia, GRN-Related Frontotemporal .
Dementia, Semantic .
Dementia, Ubiquitin-Positive Frontotemporal .
Dementias, Frontotemporal .
Dementias, Frontotemporal Lobe .
Dementias, Frontotemporal Lobe (FLDEM) .
Dementias, GRN-Related Frontotemporal .
Dementias, Semantic .
Dementias, Ubiquitin-Positive Frontotemporal .
Disease, Familial Pick's .
Disease, Wilhelmsen-Lynch .
Diseases, Familial Pick's .
Diseases, Wilhelmsen-Lynch .
Disinhibition Dementia Parkinsonism Amyotrophy Complex .
Disinhibition Dementia Parkinsonism Amytrophy Complex .
Disinhibition-Dementia-Parkinsonism-Amyotrophy Complices .
Disinhibition-Dementia-Parkinsonism-Amytrophy Complices .
FTLD with TDP 43 Pathology .
Familial Pick Disease .
Familial Pick's Diseases .
Familial Picks Disease .
Frontotemporal Dementia with Parkinsonism 17 .
Frontotemporal Dementia, GRN-Related .
Frontotemporal Dementia, Ubiquitin Positive .
Frontotemporal Dementias .
Frontotemporal Dementias, GRN-Related .
Frontotemporal Dementias, Ubiquitin-Positive .
Frontotemporal Lobar Degeneration With Ubiquitin Positive Inclusions .
Frontotemporal Lobe Dementias .
Frontotemporal Lobe Dementias (FLDEM) .
GRN Related Frontotemporal Dementia .
GRN-Related Frontotemporal Dementias .
Lobe Dementia, Frontotemporal .
Lobe Dementias, Frontotemporal .
Pick's Disease, Familial .
Pick's Diseases, Familial .
Semantic Dementias .
Ubiquitin-Positive Frontotemporal Dementia .
Ubiquitin-Positive Frontotemporal Dementias .
Wilhelmsen Lynch Disease .
Wilhelmsen-Lynch Diseases .
The most common clinical form of FRONTOTEMPORAL LOBAR DEGENERATION, this dementia presents with personality and behavioral changes often associated with disinhibition, apathy, and lack of insight. .
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631813
 
GAP-43 Protein .
GAP43 Protein .
Phosphoprotein B-50 .
Phosphoprotein F1 .
Phosphoprotein pp46 .
B 50 Protein .
GAP 43 Protein .
Growth Associated Protein 43 .
Nerve Growth Cone Membrane Protein GAP 43 .
Phosphoprotein B 50 .
B-50 Protein .
Nerve Growth Cone Membrane Protein GAP-43 .
GAP-43 .
Neuromodulin .
Growth-Associated Protein 43 .
A nervous tissue specific protein which is highly expressed in NEURONS during development and NERVE REGENERATION. It has been implicated in neurite outgrowth, long-term potentiation, SIGNAL TRANSDUCTION, and NEUROTRANSMITTER release. (From Neurotoxicology 1994;15(1):41-7) It is also a substrate of PROTEIN KINASE C. .
0.53
12254