Tumor Necrosis Factors. TNF Receptor Ligands . Tumor Necrosis Factor Superfamily Ligands . Necrosis Factors, Tumor . Receptor Ligands, TNF . TNF 26382 . A family of proteins that were originally identified by their ability to cause NECROSIS of NEOPLASMS. Their necrotic effect on cells is mediated through TUMOR NECROSIS FACTOR RECEPTORS which induce APOPTOSIS. . 1.00
Receptors, Tumor Necrosis Factor, Type I. CD 120a Antigen . CD120a Antigen . TNFR p60 . TNFR-I . TNFR1 . TNFRSF1A (Tumor Necrosis Factor Receptor Superfamily, Member 1A) . TNFRSF1A Receptor . Tumor Necrosis Factor Receptor 1A . Tumor Necrosis Factor Receptor Type 1 . 120a Antigen, CD . Antigen, CD 120a . Antigen, CD120a . Receptor, TNFRSF1A . Antigens, CD120a . CD120a Antigens . Receptors, Tumor Necrosis Factor, Member 1A . Tumor Necrosis Factor Receptor Superfamily, Member 1A . Tumor Necrosis Factor Receptor Type I . A tumor necrosis factor receptor subtype that has specificity for TUMOR NECROSIS FACTOR ALPHA and LYMPHOTOXIN ALPHA. It is constitutively expressed in most tissues and is a key mediator of tumor necrosis factor signaling in the vast majority of cells. The activated receptor signals via a conserved death domain that associates with specific TNF RECEPTOR-ASSOCIATED FACTORS in the CYTOPLASM. . 0.42
Tumor Necrosis Factor-alpha. Cachectin-Tumor Necrosis Factor . TNF Superfamily, Member 2 . TNFalpha . Tumor Necrosis Factor . Cachectin Tumor Necrosis Factor . Tumor Necrosis Factor alpha . Cachectin . TNF-alpha . Tumor Necrosis Factor Ligand Superfamily Member 2 . Tumor Necrosis Factor . Serum glycoprotein produced by activated MACROPHAGES and other mammalian MONONUCLEAR LEUKOCYTES. It has necrotizing activity against tumor cell lines and increases ability to reject tumor transplants. Also known as TNF-alpha, it is only 30% homologous to TNF-beta (LYMPHOTOXIN), but they share TNF RECEPTORS. . 0.40
Lymphotoxin-alpha. Lymphotoxin . Lymphotoxin-alpha3 . Soluble Lymphotoxin-alpha . alpha-Lymphotoxin . Lymphotoxin alpha . Lymphotoxin alpha3 . Lymphotoxin-alpha, Soluble . Soluble Lymphotoxin alpha . Tumor Necrosis Factor beta . alpha Lymphotoxin . TNF Superfamily, Member 1 . TNF-beta . Tumor Necrosis Factor-beta . Tumor Necrosis Factor Ligand Superfamily Member 1 . A tumor necrosis factor family member that is released by activated LYMPHOCYTES. Soluble lymphotoxin is specific for TUMOR NECROSIS FACTOR RECEPTOR TYPE I; TUMOR NECROSIS FACTOR RECEPTOR TYPE II; and TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY, MEMBER 14. Lymphotoxin-alpha can form a membrane-bound heterodimer with LYMPHOTOXIN-BETA that has specificity for the LYMPHOTOXIN BETA RECEPTOR. . 0.39
