Tripartite Motif Proteins. RBCC Protein Family . RBCC Proteins . TRIM Protein Family . TRIM Proteins . Family, RBCC Protein . Family, TRIM Protein . Motif Proteins, Tripartite . Protein Family, RBCC . Protein Family, TRIM . Proteins, RBCC . Proteins, TRIM . Proteins, Tripartite Motif . A protein family defined by the presence of three ZINC FINGER domains, one of which is a RING FINGER DOMAIN, a coiled-coil region, and a highly variable C-terminal region. They function in many cellular processes including APOPTOSIS and CELL CYCLE regulation. . 0.68
Tumor Necrosis Factor alpha-Induced Protein 3. TNFAIP3 Protein . Zinc Finger Protein A20 . Tumor Necrosis Factor alpha Induced Protein 3 . A UBIQUITIN editing enzyme that functions as both a ubiquitin ligase and deubiquitinase. It contains several ZINC FINGERS and functions in the immune response and INFLAMMATION by modulating signals from TNF-ALPHA; IL1-BETA; or pathogens via TOLL-LIKE RECEPTORS to terminate NF-KAPPA B activity. . 0.65
Tumor Necrosis Factor Ligand Superfamily Member 14. HVEM-L Protein . Herpesvirus Entry Mediator-Ligand Protein . TNF Superfamily, Member 14 . TNFSF14 Protein . HVEM L Protein . Herpesvirus Entry Mediator Ligand Protein . LIGHT Protein . A member of tumor necrosis factor superfamily found on activated LYMPHOCYTES and MONOCYTES. It occurs as transmembrane protein that can be cleaved to release a secreted form that specifically binds to LYMPHOTOXIN BETA RECEPTOR and TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY, MEMBER 14. . 0.61
Receptor Activator of Nuclear Factor-kappa B. CD265 Antigen . NF-KappaB Receptor Activator . RANK Protein . Receptor Activator of NF-kappa B . Receptor Activator of NF-kappaB . Receptor Activator of Nuclear Factor-kappaB . TNFRSF11A Protein . TRANCE Receptor . TRANCE-R . Activator, NF-KappaB Receptor . Antigen, CD265 . NF Kappa B Receptor Activator . NF KappaB Receptor Activator . Receptor Activator of NF kappa B . Receptor Activator of NF kappaB . Receptor Activator of Nuclear Factor kappa B . Receptor Activator of Nuclear Factor kappaB . Receptor Activator, NF-KappaB . TRANCE R . NF-Kappa B Receptor Activator . Receptors, Tumor Necrosis Factor, Member 11a . Tumor Necrosis Factor Receptor Superfamily, Member 11a . A tumor necrosis factor receptor family member that is specific for RANK LIGAND and plays a role in bone homeostasis by regulating osteoclastogenesis. It is also expressed on DENDRITIC CELLS where it plays a role in regulating dendritic cell survival. Signaling by the activated receptor occurs through its association with TNF RECEPTOR-ASSOCIATED FACTORS. . 0.58
B-Cell Activating Factor. B Cell Activating Factor . B Lymphocyte Stimulator . B-Lymphocyte Activating Factor . BLyS Protein . CD257 Antigen . TALL-1 Protein . THANK Protein . TNF Superfamily, Member 13b . TNF and APOL-Related Leukocyte Expressed Ligand 1 . TNFSF13B Protein . Activating Factor, B-Cell . Activating Factor, B-Lymphocyte . Antigen, CD257 . B Lymphocyte Activating Factor . TALL 1 Protein . TNF and APOL Related Leukocyte Expressed Ligand 1 . Antigens, CD257 . BAFF Ligand . CD257 Antigens . Tumor Necrosis Factor Ligand Superfamily Member 13b . A tumor necrosis factor superfamily member that plays a role in the regulation of B-LYMPHOCYTE survival. It occurs as a membrane-bound protein that is cleaved to release an biologically active soluble form with specificity to TRANSMEMBRANE ACTIVATOR AND CAML INTERACTOR PROTEIN; B-CELL ACTIVATION FACTOR RECEPTOR; and B-CELL MATURATION ANTIGEN. . 0.58
Tripartite Motif-Containing Protein 28. TRIM28 Protein . Tripartite Motif Containing Protein 28 . A tripartite motif protein consisting of an N-terminal RING finger, two B-box type ZINC FINGERS, and C-terminal PHD domain. It functions as a transcriptional repressor by associating with Kruppel-association box domain (KRAB domain) transcription factors and has E3-SUMO-ligase activity towards itself and also sumoylates INTERFERON REGULATORY FACTOR-7 to reduce its activity as a transcriptional activator. It can also function as a ubiquitin protein ligase towards TUMOR SUPPRESSOR PROTEIN P53. . 0.57
Promyelocytic Leukemia Protein. RNF71 Protein . TRIM19 Protein . A tripartite motif protein that contains three ZINC FINGERS, including a RING FINGER DOMAIN, at its N-terminal. Several nuclear and one cytoplasmic isoforms result from alternative splicing of the PML gene; most nuclear isoforms localize to subnuclear structures (PML nuclear bodies) that are disrupted in ACUTE PROMYELOCYTIC LEUKEMIA cells. . 0.57
