Lymphotoxin beta Receptor. Receptors, Lymphotoxin beta . TNFR Superfamily, Member 3 . Lymphotoxin beta Receptors . Receptor, Lymphotoxin beta . beta Receptor, Lymphotoxin . beta Receptors, Lymphotoxin . Tumor Necrosis Factor Receptor Superfamily, Member 3 . A member of the tumor necrosis factor receptor superfamily. It has specificity for LYMPHOTOXIN ALPHA1, BETA2 HETEROTRIMER and TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 14. The receptor plays a role in regulating lymphoid ORGANOGENESIS and the differentiation of certain subsets of NATURAL KILLER T-CELLS. Signaling of the receptor occurs through its association with TNF RECEPTOR-ASSOCIATED FACTORS. . 1.00
Lymphotoxin-beta. TNF Superfamily, Member 3 . Tumor Necrosis Factor C . beta, Lymphotoxin . Lymphotoxin beta . Tumor Necrosis Factor Ligand Superfamily Member 3 . A membrane-bound tumor necrosis family member found primarily on LYMPHOCYTES. It can form a heterotrimer (LYMPHOTOXIN ALPHA1, BETA2 HETEROTRIMER) with the soluble ligand LYMPHOTOXIN-ALPHA and anchor it to the cell surface. The membrane-bound complex is specific for the LYMPHOTOXIN BETA receptor. . 0.98
Lymphotoxin-alpha. Lymphotoxin . Lymphotoxin-alpha3 . Soluble Lymphotoxin-alpha . alpha-Lymphotoxin . Lymphotoxin alpha . Lymphotoxin alpha3 . Lymphotoxin-alpha, Soluble . Soluble Lymphotoxin alpha . Tumor Necrosis Factor beta . alpha Lymphotoxin . TNF Superfamily, Member 1 . TNF-beta . Tumor Necrosis Factor-beta . Tumor Necrosis Factor Ligand Superfamily Member 1 . A tumor necrosis factor family member that is released by activated LYMPHOCYTES. Soluble lymphotoxin is specific for TUMOR NECROSIS FACTOR RECEPTOR TYPE I; TUMOR NECROSIS FACTOR RECEPTOR TYPE II; and TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY, MEMBER 14. Lymphotoxin-alpha can form a membrane-bound heterodimer with LYMPHOTOXIN-BETA that has specificity for the LYMPHOTOXIN BETA RECEPTOR. . 0.81
Tumor Necrosis Factor-alpha. Cachectin-Tumor Necrosis Factor . TNF Superfamily, Member 2 . TNFalpha . Tumor Necrosis Factor . Cachectin Tumor Necrosis Factor . Tumor Necrosis Factor alpha . Cachectin . TNF-alpha . Tumor Necrosis Factor Ligand Superfamily Member 2 . Tumor Necrosis Factor . Serum glycoprotein produced by activated MACROPHAGES and other mammalian MONONUCLEAR LEUKOCYTES. It has necrotizing activity against tumor cell lines and increases ability to reject tumor transplants. Also known as TNF-alpha, it is only 30% homologous to TNF-beta (LYMPHOTOXIN), but they share TNF RECEPTORS. . 0.80
OX40 Ligand. CD134 Ligand . CD134L Protein . OX40L Protein . TNF Superfamily, Member 4 . Tumor Necrosis Factor (Ligand) Superfamily, Member 4 . gp34 Tumor Necrosis Factor . Tumor Necrosis Factor Ligand Superfamily Member 4 . A membrane-bound tumor necrosis family member that is expressed on activated antigen-presenting cells such as B-LYMPHOCYTES and MACROPHAGES. It signals T-LYMPHOCYTES by binding the OX40 RECEPTOR. . 0.79
CD40 Ligand. Antigen, CD154 . CD154 Antigen . CD40L . T-B Cell Activating Molecule . TNF Superfamily, Member 5 . gp39 Antigen, T-Cell . T-Cell gp39 Antigen . gp39 Antigen, T Cell . Antigens, CD154 . CD154 Antigens . Tumor Necrosis Factor Ligand Superfamily Member 5 . A membrane glycoprotein and differentiation antigen expressed on the surface of T-cells that binds to CD40 ANTIGENS on B-LYMPHOCYTES and induces their proliferation. Mutation of the gene for CD40 ligand is a cause of HYPER-IGM IMMUNODEFICIENCY SYNDROME, TYPE 1. . 0.79
TNF-Related Apoptosis-Inducing Ligand. Apo-2 Ligand . Apo-2L Protein . CD253 Antigen . TNF Superfamily, Member 10 . TRAIL Protein . Antigen, CD253 . Apo 2 Ligand . Apo 2L Protein . Apoptosis-Inducing Ligand, TNF-Related . TNF Related Apoptosis Inducing Ligand . Tumor Necrosis Factor Ligand Superfamily Member 10 . A transmembrane-protein belonging to the TNF family of intercellular signaling proteins. It is a widely expressed ligand that activates APOPTOSIS by binding to TNF-RELATED APOPTOSIS-INDUCING LIGAND RECEPTORS. The membrane-bound form of the protein can be cleaved by specific CYSTEINE ENDOPEPTIDASES to form a soluble ligand form. . 0.78
Fas Ligand Protein. CD178 Antigen . CD95 Antigen Ligand . CD95 Ligand . CD95L . Fas Ligand . Fas Ligand (FasL) . FasL Protein . TNF Superfamily, Member 6 . Antigen, CD178 . Antigens, CD178 . CD178 Antigens . Tumor Necrosis Factor Ligand Superfamily Member 6 . A transmembrane protein belonging to the tumor necrosis factor superfamily that was originally discovered on cells of the lymphoid-myeloid lineage, including activated T-LYMPHOCYTES and NATURAL KILLER CELLS. It plays an important role in immune homeostasis and cell-mediated toxicity by binding to the FAS RECEPTOR and triggering APOPTOSIS. . 0.78
RANK Ligand. CD254 Antigen . OPGL Protein . Osteoclast Differentiation Factor . Osteoprotegerin Ligand . RANKL Protein . Receptor Activator of Nuclear Factor-kappa B Ligand . Receptor Activator of Nuclear Factor-kappaB Ligand . TNF Superfamily, Member 11 . TRANCE Protein . Tumor Necrosis Factor-Related Activation-Induced Cytokine . Antigen, CD254 . Differentiation Factor, Osteoclast . Receptor Activator of Nuclear Factor kappa B Ligand . Receptor Activator of Nuclear Factor kappaB Ligand . Tumor Necrosis Factor Related Activation Induced Cytokine . Tumor Necrosis Factor Ligand Superfamily Member 11 . A transmembrane protein belonging to the tumor necrosis factor superfamily that specifically binds RECEPTOR ACTIVATOR OF NUCLEAR FACTOR-KAPPA B and OSTEOPROTEGERIN. It plays an important role in regulating OSTEOCLAST differentiation and activation. . 0.78
Tumor Necrosis Factor Ligand Superfamily Member 14. HVEM-L Protein . Herpesvirus Entry Mediator-Ligand Protein . TNF Superfamily, Member 14 . TNFSF14 Protein . HVEM L Protein . Herpesvirus Entry Mediator Ligand Protein . LIGHT Protein . A member of tumor necrosis factor superfamily found on activated LYMPHOCYTES and MONOCYTES. It occurs as transmembrane protein that can be cleaved to release a secreted form that specifically binds to LYMPHOTOXIN BETA RECEPTOR and TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY, MEMBER 14. . 0.78